Volume 26 Issue 3 | Biochemical Society Transactions

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665th Meeting

Communication

Using HOLE to predict the effects of PEG's on the conductance of α-toxin

Guy M. P. Coates; C. Lindsay Bashford; Oliver S. Smart

Biochem Soc Trans (1998) 26 (3): S193.

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Studies on the transmembrane domain of phospholamban using rotational resonance and Magic angle oriented sample spinning (MAOSS) NMR spectroscopy

Z. AHMED; D. MIDDLETON; C. GLAUBITZ; A. WATTS

Biochem Soc Trans (1998) 26 (3): S194.

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Dynamic properties of ions in models of ion channels studied by Molecular Dynamics simulation

Graham R. Smith; Mark S. P. Sansom

Biochem Soc Trans (1998) 26 (3): S195.

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Assessment of ‘Metabolism’ in an integrated medical curriculum

MARK CARROLL

Biochem Soc Trans (1998) 26 (3): S196.

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Conductimetry for enzyme teaching

A.J. Lawrence; J.G. Coote; A.G. MacLean; R. Parton; J.D. Young

Biochem Soc Trans (1998) 26 (3): S197.

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Extracellular signal-regulated kinase 1 or 2 activation by FcγRI aggregation in U937 cells

Malcolm A. B. Sim; Anne P. Barrie; Janet M. Allen

Biochem Soc Trans (1998) 26 (3): S198.

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Ectopic expression of natural resistance-associated macrophage protein-1 in COS-1 cells modulates iron accumulation

Peter G.P. Atkinson; C. Howard Barton

Biochem Soc Trans (1998) 26 (3): S199.

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Fc-Dependent Immune Regulation. Enhancement and/Suppression Directed by Antibody-Engaging Functional Fc Receptors (FcR)

CLARA G. H. BELL

Biochem Soc Trans (1998) 26 (3): S200.

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Characterization of the Fc Receptors (FcR) Functioning as Bridge Between Antibody and Cell-Effector Function: Antibody-FcR-Linked Activation of Immune Responsiveness

CLARA G. H. BELL

Biochem Soc Trans (1998) 26 (3): S201.

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Fcγ Receptors in Negative Signaling -as Potential Candidates for the Antibody Induced Regulation of Humoral Responses

CLARA G. H. BELL

Biochem Soc Trans (1998) 26 (3): S202.

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Leptin regulation of expression of Neuropeptide Y and its receptor

Stefan N. Symeonides; Margaret. J. Morris; Juan-Carlos Bournat; Janet M. Allen

Biochem Soc Trans (1998) 26 (3): S203.

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Effect of endotoxin on very-low-density lipoprotein metabolism in rat heart

David G Hole; Mark J Bennett; Rhys D Evans

Biochem Soc Trans (1998) 26 (3): S204.

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δ-Aminolevulenic acid (ALA) and the Control of Intestinal Iron Absorption

ABAS H. LAFTAH; KISHOR B. RAJA; ROBERT J. SIMPSON; TIMOTHY J. PETERS

Biochem Soc Trans (1998) 26 (3): S205.

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Growth hormone regulation of mammary glucose

Anne Faulkner

Biochem Soc Trans (1998) 26 (3): S206.

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Tissue-specific differences in rat glucocorticoid receptor gene transcriptional regulation

JAMES A. McCORMICK; VAL LYONS; JUNE NOBLE; WIETSKE ESTER; MICHAEL J. MEANEY; JONATHAN R. SECKL; KAREN E. CHAPMAN

Biochem Soc Trans (1998) 26 (3): S207.

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Heterotrophic nitrification in Paracoccus denitrificans

Lisa C. Crossman; James W.B. Moir; Stephen Spiro; David J. Richardson

Biochem Soc Trans (1998) 26 (3): S208.

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Modification of the binding pocket for the Q_A ubiquinone in the reaction centre from Rhodobacter sphaeroides

Justin P. Ridge; Matthew G. Goodwin; Marion van Brederode; Rienk van Grondelle; Michael R. Jones

Biochem Soc Trans (1998) 26 (3): S209.

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Molecular structure of an unusual cytochrome c₂ determined at 2.0Å; the cytochrome c_H from Methylobacterium extorquens

John Read; Raj Gill; Simon L. Dales; Jon B. Cooper; Steve P. Wood; Chris Anthony

Biochem Soc Trans (1998) 26 (3): S210.

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Stopped-flow studies on dimethylsulphoxide reductase from Rhodobacter capsulatus: kinetic competence of the dimethylsulphide-reduced intermediate

ANDREW T. SMITH; ROBERT C. BRAY; ALASTAIR G. McEWAN; ALAN S. McALPINE; SUE BAILEY

Biochem Soc Trans (1998) 26 (3): S211.

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The interaction of eukaryotic cytochrome b5 with flavocytochrome P-450 BM3 from Bacillus megaterium

A.W. Munro; M.A. Noble; K.L. Turner; S.K. Chapman

Biochem Soc Trans (1998) 26 (3): S212.

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Mechanistic probes of flavocytochrome P-450 BM3

M.A. Noble; K.L. Turner; S.K. Chapman; A.W. Munro

Biochem Soc Trans (1998) 26 (3): S213.

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Electron-transferring flavoprotein from Megasphaera elsdenii; gene organisation and structural information

Hugh O'neill; Stephen G. Mayhew

Biochem Soc Trans (1998) 26 (3): S214.

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Characterization of the complex of isoFMN and apoflavodoxin from Desulfovibrio vulgaris (Hildenborough)

Gary N. Yalloway; Stephen G. Mayhew

Biochem Soc Trans (1998) 26 (3): S215.

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The nrfEFG gene products are required for the activity of the cytochrome c₅₅₂ nitrite reductase from Escherichia coli

D. Eaves; J. Grove; W. Staudenmann; P. James; R. Poole; S. White; L. Griffiths; J. Cole

Biochem Soc Trans (1998) 26 (3): S216.

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The periplasmic nitrate reductase of Escherichia coli –- a comparison with the Nap systems of other bacteria

L. Potter; J. Cole

Biochem Soc Trans (1998) 26 (3): S217.

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Sexual dimorphism in the fatty acyl composition of rat adrenal lipids

J.I. Ruiz; M.B. Ruiz-Larrea

Biochem Soc Trans (1998) 26 (3): S218.

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Cell proliferation and CTP:cholinephosphate cytidylyltransferase activity in higher plants

EDWARD T. PARKIN; CAROLE E. ROLPH

Biochem Soc Trans (1998) 26 (3): S219.

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Role of lipid peroxidation in the testicular damage in experimentally varicocele induced rats

Zafer Aybek; Mehmet H. Koseoglu; Diler Aslan; Ender Duzcan; Nurten Saydam; Gul Guner

Biochem Soc Trans (1998) 26 (3): S220.

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Relationship between serum fatty acids and malondialdehyde (MDA) levels in coronary artery disease diagnosed (CAD) patients

Mehmet H. Koseoglu; Meral Fadiloglu

Biochem Soc Trans (1998) 26 (3): S221.

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S phase depletion of nuclear CTP:choline phosphate cytidylyltransferase

Alan N Hum; Graham C Burdge; Sarah M Wright; Anthony D Postle

Biochem Soc Trans (1998) 26 (3): S222.

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Chromatin-associated phosphatidylcholine synthesis

Alan N Hunt; Graham C Burdge

Biochem Soc Trans (1998) 26 (3): S223.

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Diethylstilbestrol antagonizes the oxidant-induced transformations of membrane phospholipids

M. Begoña Ruiz-Larrea; César Martin; Natalia A. Babenko; Rosa Martínez; Mercedes Lacort

Biochem Soc Trans (1998) 26 (3): S224.

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BipA affects Ca⁺⁺ fluxes and phosphorylation of the translocated intimin receptor (Tir/Hp90) in host epithelial cells infected with enteropathogenic E. coli

Michele Farris; Andrew Grant; Steve Jane; John Chad; C. David O'connor

Biochem Soc Trans (1998) 26 (3): S225.

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Analysis of phosphatidic acid molecular species using mass spectrometry

Sarah M Wright; Alan N Hunt; Anthony D Postle

Biochem Soc Trans (1998) 26 (3): S226.

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Molecular species of acidic phospholipids in human lung surfactant

Emma Heeley; Sarah Wright; David Wilton; Anthony Postle

Biochem Soc Trans (1998) 26 (3): S227.

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Interaction of the SR CaATPase with the cytoplasmic region of phospholamban

PARVEEN SHARMA; YUAN GAO; CLARE LONGLAND; FRANK MICHELANGELI; GALE STRASBURG; DIANA J. BIGELOW; VALERIE PATCHELL; S. VICTOR PERRY; BARRY A. LEVINE

Biochem Soc Trans (1998) 26 (3): S228.

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Effects of sphingosine 1-phosphate and bradykinin on phospholipid signalling in human epithelial A549 cells

V. Vasta; E. Meacci; S. Catarzi; M. Farnararo; P. Bruni

Biochem Soc Trans (1998) 26 (3): S229.

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Modulation of CTP:phosphocholine cytidylyltransferase by membrane torque tension

George S. Attard; Wendy S. Smith; Richard H. Templer; Alan N. Hunt; Suzanne Jackowski

Biochem Soc Trans (1998) 26 (3): S230.

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The okadaic acid induced ACAT activation is prevented by a specific inhibitor of the Ca²⁺/Calmodulin protein kinase II

MARÍA L. HERNÁNDEZ; MARÍA J. MARTÍNEZ; BEGOñA OCHOA

Biochem Soc Trans (1998) 26 (3): S231.

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Expression of FAT, the putative fatty acid translocator protein, is developmentally regulated in rat mammary tissue

RUSHIKA N. SUMATHIPALA; MAUREEN T. TRAVERS; PETER THOMAS; MICHAEL R. MUNDAY; ROGER A. CLEGG

Biochem Soc Trans (1998) 26 (3): S232.

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Activation of phospholipase A₂ during differentiation of human haemopoietic progenitor cells

Pamela J. Roberts; Elahe Mollapour; Michael J. Watts; David. C. Linch

Biochem Soc Trans (1998) 26 (3): S233.

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Anionic lipids and accumulation of Ca²⁺ by a Ca²⁺-ATPase

Kate A. Dalton; Sanjay Mall; Jeffrey D. Pilot; J. Malcolm East; Anthony G. Lee

Biochem Soc Trans (1998) 26 (3): S234.

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Adrenaline Induced Inhibition of Neutrophil PLA₂ Activity

YVONNE O'DOWD; PHILIP NEWSHOLME

Biochem Soc Trans (1998) 26 (3): S235.

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Phospholipase D enhances the hydrolysis of phospholipid vesicles by cytosolic phospholipase A₂

ANDREW G. BUCKLAND; DAVID C. WILTON

Biochem Soc Trans (1998) 26 (3): S236.

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Lipoprotein lipase hydrolysis of human lipoproteins measured using a fluorescence displacement assay

L. ISABEL; B. LOBO; DAVID C. WILTON

Biochem Soc Trans (1998) 26 (3): S237.

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Liver fatty acid binding protein (FABP) binds to anionic phospholipid vesicles with release of ligand

JOANNA K. DAVIES; ALFRED E.A. THUMSER; DAVID C. WILTON

Biochem Soc Trans (1998) 26 (3): S238.

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Purification and properties of an active site mutant, H48Q, of human non-pancreatic secreted phospholipase A₂

Suzanne H. Edwards; Sharon F. Baker; David C. Wilton

Biochem Soc Trans (1998) 26 (3): S239.

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β-Amyloid toxicity in rat brain reaggregate cultures

Jane Davenport Jones; Rachel Fox

Biochem Soc Trans (1998) 26 (3): S240.

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Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins

EDWARD T. PARKIN; ANTHONY J. TURNER; NIGEL M. HOOPER

Biochem Soc Trans (1998) 26 (3): S241.

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The amyloid precursor protein (APP) and the angiotensin converting enzyme (ACE) secretase are inhibited by hydroxamic acid-based inhibitors

S. Parvathy; Ishrut Hussain; Eric H. Karran; Anthony J. Turner; Nigel M. Hooper

Biochem Soc Trans (1998) 26 (3): S242.

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Full length huntingtin is not detected in intranuclear inclusions in Huntington's disease brain

Philip Thomas; Fiona Wilkinson; Nguyen thi Man; Peter S Harper; James W Neal; Glenn E Morris; A Lesley Jones

Biochem Soc Trans (1998) 26 (3): S243.

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Blood Platelets Do Not Contain the Low-Density Receptor-Related Protein (LRP)

David R. Riddell; Veeraiah Siripurapu; Dimitri V. Vinogradov; Jørgen Gliemann; James S. Owen

Biochem Soc Trans (1998) 26 (3): S244.

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Molecular characterisation of the alzheimer's amyloid precursor protein secretases

Sarah L. Houldsworth; Alison J. Trew; Nigel M. Hooper; Anthony J. Turner

Biochem Soc Trans (1998) 26 (3): S245.

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Stimulation of glyceraldehyde-3-phosphate dehydrogenase by oxyhemoglobin

Paul S. Brookes; Joanna Haley; Paul Cutler; Patrick Camilleri; John M. Land; John B. Clark; Simon J.R. Heales

Biochem Soc Trans (1998) 26 (3): S246.

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Soybean iron metabolism and nutrition

Latunde-Dada Oluyemisi

Biochem Soc Trans (1998) 26 (3): S247.

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The cloning and functional expression of human pancreatic aminopeptidase P

Graeme S. Cottrell; Ralph J. Hyde; Nigel M. Hooper; Anthony J. Turner

Biochem Soc Trans (1998) 26 (3): S248.

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Affinity purification of human IgG using immobilised, mutated immunoglobulin-binding domains from protein A of Staphylococcus aureus

Nicola L. Brown; Stephen P. Bottomley; Michael G. Gore

Biochem Soc Trans (1998) 26 (3): S249.

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A chaperonin apical domain from the thermophilic bacterium Thermus Aquaticus

Douglas J. Baker; Michael G. Gore

Biochem Soc Trans (1998) 26 (3): S250.

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Aluminosilicate particulate and β-amyloid in vitro interactions: a model of Alzheimer plaque formation

PETER EVANS; CHARLES HARRINGTON

Biochem Soc Trans (1998) 26 (3): S251.

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Transcription factor, BTF3, and the AF-1 function of the estrogen receptor

Mohammed K. K. El-Tanani; Chris D. Green

Biochem Soc Trans (1998) 26 (3): S252.

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Regulation of macrophage lipoprotein lipase by cytokines

TENGKU S. TENGKU MUHAMMAD; TIMOTHY R. HUGHES; ANTHONY CRYER; DIPAK P. RAMJI

Biochem Soc Trans (1998) 26 (3): S253.

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Use of an antisense strategy to dissect the role of MAP kinases in cellular signalling

Elizabeth M. Sale; Peter P. G. Atkinson; Caroline H. Arnott; Graham J. Sale

Biochem Soc Trans (1998) 26 (3): S254.

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Role of CBP in glucocorticoid-induced gene repression

I.M. ADCOCK; Y. NASUHARI; P.J. BARNES

Biochem Soc Trans (1998) 26 (3): S255.

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Pax-3: A role in Embryonic Cell Division, Cell Morphology or Neuronal Differentiation?

Fiona Reeves; Karen Lillycrop

Biochem Soc Trans (1998) 26 (3): S256.

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Regulation of the paired box transcription factor Pax-3

F. Reeves; R. Harris; K. Lillycrop

Biochem Soc Trans (1998) 26 (3): S257.

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Regulation of Herpes Simplex virus immediate early gene expression

Helen L. Jameson; Caroline H. Arnott; Karen A. Lillycrop

Biochem Soc Trans (1998) 26 (3): S258.

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Programmed cell death in skeletal muscle

Antonia Maglara; Malcolm J Jackson; Anne McArdle

Biochem Soc Trans (1998) 26 (3): S259.

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Glucose-dependent decreased DNA synthesis in bovine retinal endothelial cells is mediated by protein kinase C iota

Rachel M Knott; Fionna E. Keenan; Elizabeth Muckersie; Marie Robertson; John V Forrester

Biochem Soc Trans (1998) 26 (3): S260.

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DNA triple helix formation at (AT)_n tracts

Darren M. Gowers; Keith R. Fox

Biochem Soc Trans (1998) 26 (3): S261.

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ARCHAEAL EVIDENCE FOR THE ROLE OF 2′ AMINOACYLATION OF RNA IN THE ORIGIN OF AMINO ACID HOMOCHIRALITY

J. Martyn Bailey

Biochem Soc Trans (1998) 26 (3): S262.

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A proposed mechanism for the induction of Activator Protein 1 (AP-1) binding by HIV-1 Negative Factor(Nef) in the macrophage cell line RAW267.4 cells

T Biggs; C Barton; D Mann

Biochem Soc Trans (1998) 26 (3): S263.

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Molecular Cloning and Characterisation of a Novel Duodenal-Specific Gene Implicated in Iron Absorption

A.T. McKIE; K. WEHR; R.J. SIMPSON; T.J. PETERS; M.W. HENTZE; F. FARZANEH

Biochem Soc Trans (1998) 26 (3): S264.

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Identification of a novel PKD1 mutation in an Irish autosomal dominant polycystic kidney disease kindred

Orna Tighe; Michael Carmody; David T. Croke

Biochem Soc Trans (1998) 26 (3): S265.

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Studies of gene expression patterns in RER+ and RER- colon cancer cell lines

Donncha Dunican; Orna Tighe; Anne Parle-McDermott; David T. Croke

Biochem Soc Trans (1998) 26 (3): S266.

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Fibre type-specific expression of the calpain proteolytic system in skeletal muscle

Simon W Jones; Tim Parr; Paul L Sensky; Ronald G Bardsley; Peter J Buttery

Biochem Soc Trans (1998) 26 (3): S267.

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Characterisation of 8-amino-7-oxononanoate synthase: A bacterial PLP-dependent, acyl CoA condensing enzyme

Scott P. Webster; Dominic J. Campopiano; Dmitriy Alexeev; Marina Alexeeva; Rory M. Watt; Lindsay Sawyer; Robert L. Baxter

Biochem Soc Trans (1998) 26 (3): S268.

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Cysteine conjugate β-lyase activity of amino acid decarboxylases

Lorraine D. Buckberry; Rakhee Patel; Linda Hollingworth; Paul H. Teesdale-Spittle

Biochem Soc Trans (1998) 26 (3): S269.

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Site-directed mutagenesis of the quinoprotein glucose dehydrogenase of Escherichia coli; the role of His262 in PQQ binding and determination of substrate specificity

Gyles E. Cozier; Raff A. Salleh; Chris Anthony

Biochem Soc Trans (1998) 26 (3): S270.

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An investigation of flavoprotein redox partners

Lisa McIver; Claire Leadbeater; Dominic J. Campopiano; Dmitriy Alexeev; Robert L. Baxter

Biochem Soc Trans (1998) 26 (3): S271.

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Chemical modification of histidine residues in human ‘electron transferring flavoprotein’ (ETF)

ANTONY PARKER; PAUL C. ENGEL

Biochem Soc Trans (1998) 26 (3): S272.

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Structure and function studies of oxalate oxidase

Laura Requena; Stephen Bornemann

Biochem Soc Trans (1998) 26 (3): S273.

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Availability in pooled normal blood plasma of activated Hageman factor and kallikrein for contact induced coagulation

Keith J. Real; Bartholomew F. Masterson

Biochem Soc Trans (1998) 26 (3): S274.

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Two glycolytic enzymes from Sulfolobus solfataricus

G. S. E. Crowhurst; M. N. Isupov; T. Fleming; J. A. Littlechild

Biochem Soc Trans (1998) 26 (3): S275.

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Degradation rates differ between mutant and wild-type forms of phenylalanine hydroxylase expressed in vitro

Paula J. Waters; Charles R. Scriver; Michael A. Parniak

Biochem Soc Trans (1998) 26 (3): S276.

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Identification of subunit interfaces of Glycerol Dehydrogenase from Bacillus stearothermophilus

Victoria L. Drewett; Michael G. Gore

Biochem Soc Trans (1998) 26 (3): S277.

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Studies on the folding and unfolding of glycerol dehydrogenase from Bacillus stearothermophilus

Oliver Krauss; Vicky L. Drewett; Michael G. Gore

Biochem Soc Trans (1998) 26 (3): S278.

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Characterisation of domain fragments of recombinant human albumin

Susan M. Twine; Anthony G. Lee; Michael G. Gore; Brendan C. Fish; Andrew Turner; Malcolm J East

Biochem Soc Trans (1998) 26 (3): S279.

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Expression of recombinant aroB-encoded dehydroquinate synthase from pathogenic microorganisms

Murray A Skinner; Aysen Günel-Özcan; Mithila Shafiq; Duncan J Maskell; Katherine A Brown

Biochem Soc Trans (1998) 26 (3): S280.

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Site-directed mutants of the catalase-peroxidase from Mycobacterium tuberculosis

J.M. NAGY; J. JESMIN; S. SERVOS; A.E.G. CASS; K.A. BROWN

Biochem Soc Trans (1998) 26 (3): S281.

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Construction of a Pseudomonas aeruginosa Cosmid Library

PILANEE VAITHANOMSAT; SUTHA SANGIAMBUT; DEREK J. PICKARD; NEIL FAIRWEATHER; KATHERINE A. BROWN

Biochem Soc Trans (1998) 26 (3): S282.

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Molecular modelling of batroxobin on kallikreins

Lorraine Earps; Peter M. Shoolingin-Jordan

Biochem Soc Trans (1998) 26 (3): S283.

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Incubation of 6-methylsalicylic acid synthase with alternative starter units in the absence of NADPH and the identification of the resulting triaceticacid lactones

Iain D. G. Campuzano; Peter M. Shoolingin-Jordan

Biochem Soc Trans (1998) 26 (3): S284.

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Mechanistic Studies on E.coli 5-Aminolaevulinic Acid Dehydratase

Edwin Norton; Muhammad Sarwar; Peter Shoolingin-Jordan

Biochem Soc Trans (1998) 26 (3): S285.

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Dipyrromethane cofactor assembly in porphobilinogen deaminase

Luke A. McNeill; Peter M. Shoolingin-Jordan

Biochem Soc Trans (1998) 26 (3): S286.

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Cloning, isolation, expression and mutagenesis studies on the human immuno-deficiency virus type 1 (HIV-1) protease

Joanne C. Garner; Peter M. Shoolingin-Jordan

Biochem Soc Trans (1998) 26 (3): S287.

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Over-expression of the N-terminal domain of the glucagon-like peptide-1 receptor in Escherichia coli

Angie Willshaw; Dan Donnelly

Biochem Soc Trans (1998) 26 (3): S288.

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Role of Glut1 glucose transporter activation in stimulation of glucose transport by A231876 and TPA

Mehmet H. Koseoglu; F. Ismail Beigi

Biochem Soc Trans (1998) 26 (3): S289.

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The effects of thimerosal on the purified InsP₃ receptor

Mokdad Mezna; Clare L. Longland; Francesco Michelangeli

Biochem Soc Trans (1998) 26 (3): S290.

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Cross-linking analysis of rabbit skeletal muscle dystrophin

DENISE M. FINN; KAY OHLENDIECK

Biochem Soc Trans (1998) 26 (3): S291.

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Oligomerisation of calsequestrin from rabbit skeletal muscle

PATRICIA B. MAGUIRE; NIALL J. LENNON; KAY OHLENDIECK

Biochem Soc Trans (1998) 26 (3): S292.

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Cellular localisation of the most common mutant form of the CF gene protein, ΔF508–CFTR

M. Rachel Morris; Malcolm M.C. Pereira; Maurice B. Hallett; Margaret A. McPherson; Robert L. Dormer

Biochem Soc Trans (1998) 26 (3): S293.

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Localisation and dynamics of receptor-insulin contacts by NMR studies on the human insulin receptor ectodomain

ERIK SCHAEFER; YUAN GAO; DIETRICH BRANDENBURG; WILLI THEVIS; HANS G. GATTNER; LELAND E. ELLIS; BARRY A. LEVINE

Biochem Soc Trans (1998) 26 (3): S294.

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Use of cross-linking to investigate protien interactions with E. coli penicillin binding protein 4

R. Swan; I. Kimberley; D. A. Phoenix

Biochem Soc Trans (1998) 26 (3): S295.

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An investigation into the lipid interactions of peptides corresponding to the C-terminal anchoring domains of Escherichia coli penicillin-binding proteins 4 and 5

Frederick Harris; Andre Wiese; Klaus Brandenberg; David Phoenix; Ulrich Seydel

Biochem Soc Trans (1998) 26 (3): S296.

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Solid state NMR studies of ligands bound to the nicotinic acetylcholine receptor

Philip T.F. Williamson; J. Watts; G. Gröbner; K.W. Miller; A. Watts

Biochem Soc Trans (1998) 26 (3): S297.

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Localization of endoplasmic reticulum in living cells using green fluorescent protein chimeras

Iris D. A. van Goethem; Phil Adams; John E. Chad; Andrea M. Mather; Barbara Griffiths; Anthony G. Lee; J. Malcolm East

Biochem Soc Trans (1998) 26 (3): S298.

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Identification of endoplasmic reticulum targeting signals using SERCA/PMCA chimeras

John P.J. Black; John E. Chad; Anthony G. Lee; J. Malcolm East

Biochem Soc Trans (1998) 26 (3): S299.

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Electrostatics of ligand-gated ion channels

Charlotte Adcock; Graham R. Smith; Mark S. P. Sansom

Biochem Soc Trans (1998) 26 (3): S300.

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Molecular dynamics of ion/channel interactions [1]

Kishani M. Ranatunga; Ian D. Kerr; Charlotte A. Adcock; Graham R. Smith; Mark S. P. Sansom

Biochem Soc Trans (1998) 26 (3): S301.

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Peptide-Bilayer Interactions:- Simulation studies

Paolo La Rocca; Mark S. P. Sansom

Biochem Soc Trans (1998) 26 (3): S302.

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Simulations of the M2 Channel for Influenza A Virus

Lucy R. Forrest; Mark S.P. Sansom

Biochem Soc Trans (1998) 26 (3): S303.

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Cell-free synthesis and assembly of connexins into functional gap junction hemichannels

Shoeb Ahmad; Juan Diez Iriondo; W.Howard Evans

Biochem Soc Trans (1998) 26 (3): S304.

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The effect of mastoparan on the E2-E1 transition of the SR Ca²⁺-ATPase

Clare L. Longland; Francesco Michelangeli

Biochem Soc Trans (1998) 26 (3): S305.

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Effect of the D³²N and N³⁰⁰F mutations on the activity of the bacterial sugar transport protein, GalP

Neil M. Sanderson; Dong Qi; Angela Steel; Peter J.F. Henderson

Biochem Soc Trans (1998) 26 (3): S306.

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Interaction of calpastatin isoforms with L-type Ca²⁺ channels

ESTHER HALL; ANDREW K. LOCKLEY; TIM PARR; RONALD G. BARDSLEY

Biochem Soc Trans (1998) 26 (3): S307.

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Structure and conformation of the retinal chromophore in bovine rhodopsin

G. Groebner; I. Burnett; G. Chol; C. Glaubitz; J. Mason; A. Watts

Biochem Soc Trans (1998) 26 (3): S308.

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Transmembrane alpha-helices in phospholipid bilayers

R.J. Webb; A.G. Lee; R.P. Sharma; J.M. East

Biochem Soc Trans (1998) 26 (3): S309.

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Flexible hinges in dystrophin

Naseem AHMED; Nguyen thi MAN; Glenn E. MORRIS

Biochem Soc Trans (1998) 26 (3): S310.

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Membrane Protein Structure: the Domain Approach

Modelling the packing of transmembrane helices: application to aquaporin-1

M. S. P. Sansom; I. D. Kerr; R. Law; L. Davison; D. P. Tieleman

Biochem Soc Trans (1998) 26 (3): 509–515.

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Studies on the structure of a transmembrane region and a cytoplasmic loop of the human red cell anion exchanger (band 3, AE1)

E. J. Chambers; D. Askin; G. B. Bloomberg; S. M. Ring; M. J. A. Tanner

Biochem Soc Trans (1998) 26 (3): 516–520.

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Structure of the G-protein-coupled receptor, rhodopsin: a domain approach

P. L. Yeagle; A. D. Albert

Biochem Soc Trans (1998) 26 (3): 520–531.

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Mechanistic aspects of energy coupling in the Escherichia coli mannitol phosphotransferase system: a domain approach

G. T. Robillard; W. Meijberg; G. Schuurman-Wolters

Biochem Soc Trans (1998) 26 (3): 532–538.

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How cytidylyltransferase uses an amphipathic helix to sense membrane phospholipid composition

R. B. Cornell

Biochem Soc Trans (1998) 26 (3): 539–544.

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The role of heparin in the complex formation between fibroblast growth factor 2 and its high affinity receptor: comparative modelling and biochemical studies

L. Pellegrini; P. Commander; B. Mulloy; M. Martin-Martinez; T. L. Blundell; D. F. Burke

Biochem Soc Trans (1998) 26 (3): 545–549.

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Modelling and Membrane Proteins

Towards structural genomics for transmembrane proteins

D. T. Jones; W. R. Taylor

Biochem Soc Trans (1998) 26 (3): 429–438.

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Molecular dynamics simulations of membranes with embedded proteins and peptides: porin, alamethicin and influenza virus M2

M. S. P. Sansom; D. P. Tieleman; L. R. Forrest; H. J. C. Berendsen

Biochem Soc Trans (1998) 26 (3): 438–443.

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Helical structure and dynamics in membrane polypeptides

C. E. Dempsey; R. B. Sessions; A. Halsall; J. Takei; N. Gibbs; M. T. Young

Biochem Soc Trans (1998) 26 (3): 444–450.

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Three-dimensional models of glutamate receptors

M. J. Sutcliffe; A. H. Smeeton; Z. G. Wo; R. E. Oswald

Biochem Soc Trans (1998) 26 (3): 450–458.

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Structure and Mechanism of Enzymes

Mechanistic and structural studies on methylmalonyl-CoA mutase

N. H. Thomä; P. F. Leadlay

Biochem Soc Trans (1998) 26 (3): 293–298.

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Swinging arms in multifunctional enzymes and the specificity of post-translational modification

R. N. Perham; P. A. Reche

Biochem Soc Trans (1998) 26 (3): 299–303.

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S-Adenosylmethionine: a ‘poor man's coenzyme B₁₂’ in the reaction of lysine 2,3-aminomutase

P. A. Frey; M. D. Ballinger; G. H. Reed

Biochem Soc Trans (1998) 26 (3): 304–310.

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Enzymes that exploit imines – one way or the other

C. Abell

Biochem Soc Trans (1998) 26 (3): 310–315.

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Preparation and properties of 6-substituted cyclohexane-1,2,4-triol derivatives: mechanistic probes for the inositol monophosphatase reaction

J. Schulz; J. Wilkie; M. W. Beaton; D. J. Miller; D. Gani

Biochem Soc Trans (1998) 26 (3): 315–322.

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A discussion on the activation of oxygen in chemistry and enzymology

M. Akhtar; P. Lee-Robichaud; J. N. Wright; M. E. Akhtar

Biochem Soc Trans (1998) 26 (3): 322–325.

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Structure and mechanism of enzymes involved in the assembly of the tetrapyrrole macrocycle

P. M. Shoolingin-Jordan

Biochem Soc Trans (1998) 26 (3): 326–336.

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Suspect Proteins in Neurodegeneration

Fibrillogenesis of β-amyloid

D. Allsop; D. Howlett; G. Christie; E. Karran

Biochem Soc Trans (1998) 26 (3): 459–463.

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Intraneuronal filamentous tau protein and α-synuclein deposits in neurodegenerative diseases

M. Goedert; R. Jakes; R. A. Crowther; M. Hasegawa; M. J. Smith; M. G. Spillantini

Biochem Soc Trans (1998) 26 (3): 463–471.

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Polyglutamine expansion and Huntington's disease

G. P. Bates; L. Mangiarini; E. E. Wanker; S. W. Davies

Biochem Soc Trans (1998) 26 (3): 471–475.

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Copper, zinc superoxide dismutase (SODI) and its role in neuronal function and disease with particular relevance to motor neurone disease/amyotrophic lateral sclerosis

J. de Belleroche; R. W. Orrell; L. Virgo; J. Habgood; I. M. Gardiner; A. Malaspina; N. Kaushik; J. Mitchell; J. Greenwood

Biochem Soc Trans (1998) 26 (3): 476–480.

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The three-dimensional structure of prion protein: implications for prion disease

M. A. Baldwin; T. L. James; F. E. Cohen; S. B. Prusiner

Biochem Soc Trans (1998) 26 (3): 481–486.

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Amyloid fibres of Sup35 support a prion-like mechanism of inheritance in yeast

S. Lindquist; S. K. DebBurman; J. R. Glover; A. S. Kowal; J.-J. Liu; E. C. Schirmer; T. R. Serio

Biochem Soc Trans (1998) 26 (3): 486–490.

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Presenilins – in search of functionality

E. H. Karran; D. Allsop; G. Christie; J. Davis; C. Gray; F. Mansfield; R. V. Ward

Biochem Soc Trans (1998) 26 (3): 491–496.

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The Fe65 and XII families of proteins: proteins that interact with the Alzheimer's disease amyloid precursor protein

D. M. McLoughlin; N. G. Irving; C. C. J. Miller

Biochem Soc Trans (1998) 26 (3): 497–500.

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Characterization of β-secretase

D. J. Stephens; B. M. Austen

Biochem Soc Trans (1998) 26 (3): 500–504.

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Transgenic mouse models of Alzheimer's disease

D. J. S. Sirinathsinghji

Biochem Soc Trans (1998) 26 (3): 504–508.

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The Diversity of Bacterial Redox Proteins

Consideration of a phlorin structure for haem P-460 of hydroxylamine oxidoreductase and its implications regarding reaction mechanism

D. M. Arciero; A. B. Hooper

Biochem Soc Trans (1998) 26 (3): 385–389.

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Dimethylsulphoxide reductase from purple phototrophic bacteria: structures and mechanism(s)

A. G. McEwan; G. R. Hanson; S. Bailey

Biochem Soc Trans (1998) 26 (3): 390–396.

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Structural bases for the catalytic mechanism of [NiFe] hydrogenases

E. Garcin; Y. Montet; A. Volbeda; C. Hatchikian; M. Frey; J. C. Fontecilla-Camps

Biochem Soc Trans (1998) 26 (3): 396–401.

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The diversity of redox proteins involved in bacterial heterotrophic nitrification and aerobic denitrification

D. J. Richardson; J.-M. Wehrfritz; A. Keech; L. C. Crossman; M. D. Roldan; H. J. Sears; C. S. Butler; A. Reilly; J. W. B. Moir; B. C. Berks; S. J. Ferguson; A. J. Thomson; S. Spiro

Biochem Soc Trans (1998) 26 (3): 401–408.

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The membrane-integral domain of succinate:quinone oxidoreductases –- a secretive haem-containing domain

L. Hederstedt

Biochem Soc Trans (1998) 26 (3): 408–413.

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The pyrroloquinoline quinone (PQQ)-containing quinoprotein dehydrogenases

C. Anthony

Biochem Soc Trans (1998) 26 (3): 413–417.

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Structure and function of flavocytochrome c₃, the soluble fumarate reductase from Shewanella NCIMB400

G. A. Reid; E. H. J. Gordon; A. E. Hill; M. Doherty; K. Turner; R. Holt; S. K. Chapman

Biochem Soc Trans (1998) 26 (3): 418–421.

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Protein engineering of the photoreaction centre from Rhodobacter sphaeroides

J. P. Ridge; M. G. Goodwin; M. R. Jones

Biochem Soc Trans (1998) 26 (3): 422–427.

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The Molecular Structure of Phospholipids and the Regulation of Cell Function

Why has phosphatidylethanolamine N-methyltransferase survived in evolution?

D. E. Vance; C. J. Walkey; L. B. Agellon

Biochem Soc Trans (1998) 26 (3): 337–340.

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Binding of bee venom and human group IIa phospholipases A₂ to membranes: a minor role for electrostatics

Y. Lin; F. Ghomashchi; R. Nielsen; Y. Snitko; B.-Z. Yu; S. K. Han; W. Cho; D. C. Wilton; M. K. Jain; B. H. Robinson; M. H. Gelb

Biochem Soc Trans (1998) 26 (3): 341–345.

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Activation of calcium-independent phospholipase A₂ by depletion of internal calcium stores

R. W. Gross

Biochem Soc Trans (1998) 26 (3): 345–349.

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Regulation of cytosolic phospholipase A₂ by phosphorylation

A. G. Börsch-Haubold

Biochem Soc Trans (1998) 26 (3): 350–354.

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The structure of phospholipase C isoforms and the regulation of phosphoinositide hydrolysis

S. James

Biochem Soc Trans (1998) 26 (3): 354–359.

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The effects of phospholipid structure on the function of a calcium pump

A. G. Lee; J. M. East

Biochem Soc Trans (1998) 26 (3): 359–365.

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Why is docosahexaenoic acid essential for nervous system function?

D. C. Mitchell; K. Gawrisch; B. J. Litman; N. Salem, Jr.

Biochem Soc Trans (1998) 26 (3): 365–370.

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The role of lysophosphatide acyltransferases and protein kinase C isoforms in the regulation of lymphocyte responses

M. Szamel; V. Kaever; H. Leufgen; K. Resch

Biochem Soc Trans (1998) 26 (3): 370–374.

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The non-specific lipid transfer protein (sterol carrier protein 2) acts as a peroxisomal fatty acyl-CoA binding protein

K. W. A. Wirtz; F. S. Wouters; P. H. Bastiaens; R. J. A. Wanders; U. Seedorf; T. M. Jovin

Biochem Soc Trans (1998) 26 (3): 374–378.

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Anionic phospholipids and the regulation of cell functions

D. C. Wilton

Biochem Soc Trans (1998) 26 (3): 378–383.

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Royal Irish Academy Lecture

Peptide Metabolism in Cytoplasm of Brain Cells

G. O'Cuinn

Biochem Soc Trans (1998) 26 (3): 279–292.

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Issues

Cover Image

665th Meeting

Communication

Membrane Protein Structure: the Domain Approach

Modelling and Membrane Proteins

Structure and Mechanism of Enzymes

Suspect Proteins in Neurodegeneration