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February 2002
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ISSN 0300-5127
EISSN 1470-8752
In this Issue
675th York Meeting
Complexities in ETS-domain transcription factor function and regulation
Biochem Soc Trans (2002) 30 (1): A1.
Experimental and bioinformatic approaches to functional genomics
Biochem Soc Trans (2002) 30 (1): A1.
Glycogenomics: The Impact of Genomics and Informatics in Glycobiology
Genomic and RNA interference screens targeted at O-glycosylation in C. elegans
Biochem Soc Trans (2002) 30 (1): A1.
Heparan sulphate without 2-O-sulphation can promote signalling by FGF-1, FGF-2 and HGF
Biochem Soc Trans (2002) 30 (1): A2.
Genomic analysis of novel Siglecs (sialic acid binding Ig-type lectins)
Biochem Soc Trans (2002) 30 (1): A3.
Large scale mapping of oligosaccharide heterogeneity (glycomes)
Biochem Soc Trans (2002) 30 (1): A4.
The glycome of Caenorhabditis elegans and other model organisms
Biochem Soc Trans (2002) 30 (1): A4.
Microarray for glycobiologists: analysis of cellular glycosylation changes
Biochem Soc Trans (2002) 30 (1): A4.
GlycoChip™ - high throughput technology for screening and analysis of protein-glycan interactions
Biochem Soc Trans (2002) 30 (1): A4.
Metabolite Channelling and Metabolic Complexity
Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease
Biochem Soc Trans (2002) 30 (1): A6.
Multiple glucose 6-phosphate pools or channelling in multiple pathways?
Biochem Soc Trans (2002) 30 (1): A6.
Structural biology of multiprotein complexes involved in extracellular, cytoplasmic, and nuclear signals
Biochem Soc Trans (2002) 30 (1): A7.
Substrate channelling in the pyruvate dehydrogenase multienzyme complex
Biochem Soc Trans (2002) 30 (1): A7.
The cAMP cascade and mitochondrial oxidative phosphorylation. Physiopathological implications
S. Papa; A.M. Sardanelli; S. Scacco; V. Petruzzella; Z. Technikova-Dobrova; A. Gaballo; A. Signorile
Biochem Soc Trans (2002) 30 (1): A7.
Sequential extracts of human bone shows differing collagen synthetic rates
Biochem Soc Trans (2002) 30 (1): A8.
Calmodulin conformational changes in the activation of protein kinases
Biochem Soc Trans (2002) 30 (1): A8.
Skeletal Muscle Energetics and Exercise Tolerance
Energetics of muscle contraction: the whole is less than the sum of its parts
Biochem Soc Trans (2002) 30 (1): A8.
Evolving techniques for investigation of muscle bioenergetics and oxygenation
Biochem Soc Trans (2002) 30 (1): A9.
Measuring real levels of oxygen in vivo: opportunities and challenges
Biochem Soc Trans (2002) 30 (1): A9.
Adipose tissue, the immune system and exercise fatigue: how activated lymphocytes compete for lipids
Biochem Soc Trans (2002) 30 (1): A10.
The acetyl-group deficit limits mitochondrial ATP production at the onset of exercise
Biochem Soc Trans (2002) 30 (1): A10.
Different modes of phosphofructokinase (PFK) activation in working vertebrate muscle
Biochem Soc Trans (2002) 30 (1): A10.
Staying Healthy with Chips. The Future of Diagnosis
Fish and chips: unraveling the interactions between genetic and dietary factors in determining cardiovascular risk
Biochem Soc Trans (2002) 30 (1): A11.
Functional genomic approaches to understanding heritable and acquired disorders of connective tissue
Biochem Soc Trans (2002) 30 (1): A11.
Affymetrix microarray technology: present and future applications
Biochem Soc Trans (2002) 30 (1): A12.
Application of disposable plastic microfluidic device arrays with customized chemistries to multiplexed biochemical assays
Biochem Soc Trans (2002) 30 (1): A12.
Geniom Technology: exploring natures plasticity with a flexible probing tool - and finding new ways for its electronic distribution
Biochem Soc Trans (2002) 30 (1): A12.
The ProteinChip® Biology System from Ciphergen Biosystems: a novel proteomics platform for rapid biomarker discovery and validation
Biochem Soc Trans (2002) 30 (1): A13.
Non-Haemostatic Role for Blood Coagulation Proteases and their Receptors
Extracellular proteolysis in development and progression of atherosclerosis
Biochem Soc Trans (2002) 30 (1): A13.
Structural analysis of the interaction between urokinase and its receptor - a potential target for anti-invasive cancer therapy
Biochem Soc Trans (2002) 30 (1): A13.
Hemostatic factors occupy new territory: The role of the urokinase receptor system and kininogen in inflammation
Biochem Soc Trans (2002) 30 (1): A13.
The urokinase receptor as an effector of G protein-coupled receptors
Biochem Soc Trans (2002) 30 (1): A14.
Signal transduction via the urokinase receptor: role in cell migration and proliferation
Biochem Soc Trans (2002) 30 (1): A14.
Role of thrombin and its major cellular receptor, proteaseactivated receptor-1, in experimental pulmonary fibrosis
Biochem Soc Trans (2002) 30 (1): A14.
Inhibition of tissue factor activity reduces the density of cellular network formation in an in vitro model of angiogenesis
Biochem Soc Trans (2002) 30 (1): A15.
Urokinase plasminogen activator, a potent marker of metastatic potential in human cancer
Biochem Soc Trans (2002) 30 (1): A16.
Altering outcome in septic shock using a novel therapeutic approach with protein C / activated protein c concentrates
Biochem Soc Trans (2002) 30 (1): A17.
RNA-Protein Machine
Structure of a hepatitis C virus IRES RNA motif recognized by translation initiation factor 3
José Gallego; Roscoe Klinck; A. Collier; G. Harrison; S. Harris; Paul T. Cole; Fareed Aboul-Ela; Gabriele Varani; S. Walker
Biochem Soc Trans (2002) 30 (1): A18.
Bacterial mRNA decay: structure and function of the E. coli degradosome
Biochem Soc Trans (2002) 30 (1): A19.
Expanding the genetic code: Selenocysteine insertion into proteins
Biochem Soc Trans (2002) 30 (1): A19.
Assembly and function of protein-RNA sub-complexes of the mammalian signal recognition particle
Biochem Soc Trans (2002) 30 (1): A20.
Regulatory roles for the ribosome in protein targeting to the endoplasmic reticulum
Biochem Soc Trans (2002) 30 (1): A20.
Proteases and Anti-Proteases: Molecular Mechanisms and Novel Therapeutic Targets
Hypersensitive mouse traps, α1-antitrypsin deficiency and dementia
Biochem Soc Trans (2002) 30 (1): A20.
Gene regulation of the serine proteinase inhibitors α1-antitrypsin and α1-antichymotrypsin
Biochem Soc Trans (2002) 30 (1): A20.
Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration
Biochem Soc Trans (2002) 30 (1): A22.
The role of plasminogen activators in peritoneal adhesion formation
Biochem Soc Trans (2002) 30 (1): A22.
Biochemistry in the Curricula of Professions Allied to Medicine
Physiological measurements technicians - the challenge of biochemistry
Biochem Soc Trans (2002) 30 (1): A23.
The rational & teaching of biochemistry within complementary medicine
Biochem Soc Trans (2002) 30 (1): A24.
Plant Glyco-Related Genomics
Structural genomics of carbohydrate-active enzymes: implications for the synthesis of plant polysaccharides
Biochem Soc Trans (2002) 30 (1): A24.
Functional genomics of the Arabidopsis multigene family of glycosyltransferases involved in cellular homeostasis
Biochem Soc Trans (2002) 30 (1): A25.
Developing Skills Through Undergraduate Work Placements
The placement triangle: employer, student, university relationships
Biochem Soc Trans (2002) 30 (1): A25.
Amino alditols as inhibitors of mycobacterial cell wall biosynthesis
Biochem Soc Trans (2002) 30 (1): A27.
The role of IgG1-Fc oligosaccharide residues in FcγRIIb binding
Biochem Soc Trans (2002) 30 (1): A27.
Generation and phenotyping of a Trypanosoma brucei Glucosidase II null mutant
Biochem Soc Trans (2002) 30 (1): A27.
A fingerprinting method for chondroitin / dermatan sulphate and hyaluronan oligosaccharides
Biochem Soc Trans (2002) 30 (1): A28.
Neoglyconjugate IgG-Fc molecules have enhanced function relative to aglycosylated IgG-Fc
Biochem Soc Trans (2002) 30 (1): A28.
Heparan sulphate without 2-O-sulphation can promote signalling by FGF-1, FGF-2 and HGF
Biochem Soc Trans (2002) 30 (1): A28.
Dietary vitamin E reduces plasma and liver markers of oxidant stress in the aluminium treated rat
Biochem Soc Trans (2002) 30 (1): A30.
Control of electron transfer in Schizosaccharomyces pombe mitochondria
Biochem Soc Trans (2002) 30 (1): A30.
Sequential extracts of human bone shows differing collagen synthetic rates
Biochem Soc Trans (2002) 30 (1): A30.
A NMR study of nutrient metabolism in the pancreatic beta cell-line BRIN-BD11
L. Brennan; A. Shine; C. Hewage; K. M. Brindle; J.P.G. Malthouse; N.H. McClenaghan; P. R. Flatt; P. Newsholme
Biochem Soc Trans (2002) 30 (1): A31.
Hepatic intralobular heterogeneity of glucose and glycogen metabolism
Biochem Soc Trans (2002) 30 (1): A31.
Over-expression of a mitochondrially-located HSP70 alters carbon metabolism in tobacco
Biochem Soc Trans (2002) 30 (1): A31.
Functional genomics via the metabolome: multivariate FANCY strategy for characterising genes of unknown function
Biochem Soc Trans (2002) 30 (1): A31.
Investigations into the allosteric mechanism of a trimeric mutant of Clostridial glutamate dehydrogenase
Biochem Soc Trans (2002) 30 (1): A32.
The cAMP cascade and mitochondrial oxidative phosphorylation. Physiopathological implications
S. Papa; A.M. Sardanelli; S. Scacco; V. Petruzzella; Z. Technikova-Dobrova; A. Gaballo; A. Signorile
Biochem Soc Trans (2002) 30 (1): A32.
Calmodulin conformational changes in the activation of protein kinases
Biochem Soc Trans (2002) 30 (1): A33.
Why does G6PDH deficiency increase susceptibility to diabetes?
Biochem Soc Trans (2002) 30 (1): A33.
Effects of multiple hyperbaric oxygen treatments on blood function
Biochem Soc Trans (2002) 30 (1): A34.
Carbon monoxide toxicity in the heart: evidence for ischaemia/reperfusion like injury
Biochem Soc Trans (2002) 30 (1): A34.
Different modes of phosphofructokinase (PFK) activation in working vertebrate muscle
Biochem Soc Trans (2002) 30 (1): A34.
Comparison of energy release in intact and skinned muscle fibres during development of isometric force
Biochem Soc Trans (2002) 30 (1): A35.
Identification of antithrombotic substances in common herbs and spices
Biochem Soc Trans (2002) 30 (1): A35.
The regulation of tissue factor gene expression and activity by oxidised low-density lipoproteins
Biochem Soc Trans (2002) 30 (1): A35.
Role of thrombin and its major cellular receptor, protease-activated receptor-1, in experimental pulmonary fibrosis
Biochem Soc Trans (2002) 30 (1): A36.
The influence of tissue factor on capillary formation by endothelial and fibroblast cells
Biochem Soc Trans (2002) 30 (1): A36.
Inhibition of tissue factor activity reduces the density of cellular network formation in an in vitro model of angiogenesis
Biochem Soc Trans (2002) 30 (1): A36.
Characterisation of green fluorescent protein tagged urokinase-type plasminogen activator receptor (uPAR) variants
Biochem Soc Trans (2002) 30 (1): A37.
Influence of PPAR agonists on the procoagulant response of endothelial cells following treatment with TNF-alpha
Biochem Soc Trans (2002) 30 (1): A37.
RNA-Protein Machines
Localisation of metallothionein in CHO cells requires a 41-nucleotide sequence within the 3′untranslated region of its mRNA
Biochem Soc Trans (2002) 30 (1): A37.
HE4, an alternatively spliced WAP domain containing protein may contribute to host defence
Biochem Soc Trans (2002) 30 (1): A38.
Sequence variation of the major capsid protein of human papillomavirus type6
Biochem Soc Trans (2002) 30 (1): A38.
Investigation of the role of the serine protease HtrA in matrix calcification
Biochem Soc Trans (2002) 30 (1): A38.
The role of plasminogen activators in peritoneal adhesion formation
Biochem Soc Trans (2002) 30 (1): A39.
Expression of Drosophila angiotensin converting enzyme (Ance) during metamorphosis: regulation by 20-hydrox-yecdysone
R.J. Siviter; D. Cottam; C.M. Taylor; D. Hurst; A. Denton; P. Dani; M.J. Milner; A.D. Shirras; R.E. Isaac
Biochem Soc Trans (2002) 30 (1): A39.
The Neprilysin (NEP) family of zinc -implications for peptide signalling in Drosophila melanogaster
Biochem Soc Trans (2002) 30 (1): A40.
Peptide metabolism in C. elegans: expression and functional characterisation of a cytoplasmic aminopeptidase P
Biochem Soc Trans (2002) 30 (1): A40.
Modification of skeletal muscle regeneration by anti-proteases
Biochem Soc Trans (2002) 30 (1): A40.
The interaction of elafin (elastase-specific inhibitor) with bacterial endotoxin
Biochem Soc Trans (2002) 30 (1): A40.
Calpain expression and cleavage of MLCK in human myometrium: implications for preterm labour
Biochem Soc Trans (2002) 30 (1): A41.
The H11 group of membrane aminopeptidases; characterisation and expression
E.A. Munn; T.S. Smith; M. Graham; H. Smith; W.J. Coadwell; R. Hederer; A. Hutchings; J. Rocha; S.E. Newton; J. Sexton; V. Cook; M. Walkiewicz; D. Hasse; S. Nikolaou; D. Hartman; D. Donald
Biochem Soc Trans (2002) 30 (1): A41.
Fate of cystatin C lacking its leader sequence in retinal pigment epithelial cells
Biochem Soc Trans (2002) 30 (1): A41.
Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration
Biochem Soc Trans (2002) 30 (1): A41.
Identification of a putative cell type specific repressor activity within the NRD convertase gene promoter
Biochem Soc Trans (2002) 30 (1): A42.
Proteolytic susceptibility of secretory leucoprotease inhibitor
Biochem Soc Trans (2002) 30 (1): A42.
β2-Adrenergic receptor-induced proliferation of human cardiac fibroblasts
Biochem Soc Trans (2002) 30 (1): A42.
Characterisation of the 5′UTR region of the human cardiac troponin T gene (Genbank :AY0044273)
Biochem Soc Trans (2002) 30 (1): A42.
Mutations in the human cardiac β-myosin heavy chain protein: a molecular dynamic analysis
Biochem Soc Trans (2002) 30 (1): A43.
Curriculum content - driven by evidence of need or by policy and dogma?
Biochem Soc Trans (2002) 30 (1): A43.
Phosphoenolpyruvate carboxykinase gene (cspck) from cucumber (Cucumis sativus L.)
Biochem Soc Trans (2002) 30 (1): A44.
Transporting the Essentials: Nutrient and Micronutrient Transporters
Barrels & corks in a computer - modelling bacterial iron transport systems
Biochem Soc Trans (2002) 30 (1): A44.
The barrier properties of in vitro generated normal human urothelium
Biochem Soc Trans (2002) 30 (1): A44.
Caenorhabditis elegans as a model organism in the study of nucleoside transporters
P.J. Appleford; M. Griffiths; E.G. Chomey; S.Y.M. Yao; D. MacGregor; R.E. Isaac; I.A. Hope; D. Coates; C.E. Cass; J.D. Young; S.A. Baldwin
Biochem Soc Trans (2002) 30 (1): A44.
MISCELLANEOUS POSTERS
Examination of gene expression in yeast using microarray technology
Biochem Soc Trans (2002) 30 (1): A45.
Effects of endotoxin on surfactant function & lung mechanics in the rabbit
Biochem Soc Trans (2002) 30 (1): A46.
Protein turnover: the missing link in proteomics
J.M. Pratt; S.J. Gaskell; D.H.L. Robertson; I. Riba-Garcia; S.G. Oliver; P. Butler; J. Petty; A. Hayes; R.J. Beynon
Biochem Soc Trans (2002) 30 (1): A46.
Differential gene expression implicates protein kinase C isoenzyme activation in response to glutathione depletion in HepG2 cells
Biochem Soc Trans (2002) 30 (1): A46.
