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Volume 35, Issue 4

August 2007

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Cover Image

Cover Image
Front Matter
Table of Contents

ISSN 0300-5127

EISSN 1470-8752

In this Issue

Biochemical Society Focused Meetings

Biochemical Society Focused Meetings

Matrix Turnover: Mechanisms and Common Denominator

Factors controlling matrix turnover in health and disease

D.J. Buttle

Biochem Soc Trans (2007) 35 (4): 643–646.

Abstract

View Articletitled, Factors controlling matrix turnover in health and disease

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Regulation of matrix turnover: fibroblasts, forces, factors and fibrosis

G.J. Laurent; R.C. Chambers; M.R. Hill; R.J. McAnulty

Biochem Soc Trans (2007) 35 (4): 647–651.

Abstract

View Articletitled, Regulation of matrix turnover: fibroblasts, forces, factors and fibrosis

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Matrix synthesis and degradation in human intervertebral disc degeneration

C.L. Le Maitre; A. Pockert; D.J. Buttle; A.J. Freemont; J.A. Hoyland

Biochem Soc Trans (2007) 35 (4): 652–655.

Abstract

View Articletitled, Matrix synthesis and degradation in human intervertebral disc degeneration

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Brain matrix: structure, turnover and necessity

U. Rauch

Biochem Soc Trans (2007) 35 (4): 656–660.

Abstract

View Articletitled, Brain matrix: structure, turnover and necessity

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TGF-β, Smad3 and the process of progressive fibrosis

J. Gauldie; P. Bonniaud; P. Sime; K. Ask; M. Kolb

Biochem Soc Trans (2007) 35 (4): 661–664.

Abstract

View Articletitled, TGF-β, Smad3 and the process of progressive fibrosis

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Three-dimensional extracellular matrix culture models of EGFR signalling and drug response

P.A. Kenny

Biochem Soc Trans (2007) 35 (4): 665–668.

Abstract

View Articletitled, Three-dimensional extracellular matrix culture models of EGFR signalling and drug response

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HtrA1: a novel regulator of physiological and pathological matrix mineralization?

A.E. Canfield; K.D. Hadfield; C.F. Rock; E.C. Wylie; F.L. Wilkinson

Biochem Soc Trans (2007) 35 (4): 669–671.

Abstract

View Articletitled, HtrA1: a novel regulator of physiological and pathological matrix mineralization?

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The molecular basis of inter-α-inhibitor heavy chain transfer on to hyaluronan

C.M. Milner; W. Tongsoongnoen; M.S. Rugg; A.J. Day

Biochem Soc Trans (2007) 35 (4): 672–676.

Abstract

View Articletitled, The molecular basis of inter-α-inhibitor heavy chain transfer on to hyaluronan

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Influence of the extracellular matrix on the frictional properties of tissue-engineered cartilage

M. Plainfossé; P.V. Hatton; A. Crawford; Z.M. Jin; J. Fisher

Biochem Soc Trans (2007) 35 (4): 677–679.

Abstract

View Articletitled, Influence of the extracellular matrix on the frictional properties of tissue-engineered cartilage

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‘Rumours of my death may have been greatly exaggerated’: a brief review of cell death in human intervertebral disc disease and implications for cell transplantation therapy

W.E.B. Johnson; S. Roberts

Biochem Soc Trans (2007) 35 (4): 680–682.

Abstract

View Articletitled, ‘Rumours of my death may have been greatly exaggerated’: a brief review of cell death in human intervertebral disc disease and implications for cell transplantation therapy

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F-actin cytoskeletal organization in intervertebral disc health and disease

S. Li; V.C. Duance; E.J. Blain

Biochem Soc Trans (2007) 35 (4): 683–685.

Abstract

View Articletitled, F-actin cytoskeletal organization in intervertebral disc health and disease

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Astrocyte–leucocyte interactions and the mechanisms regulating matrix degradation in CNS tuberculosis

J.A. Green; J.S. Friedland

Biochem Soc Trans (2007) 35 (4): 686–688.

Abstract

View Articletitled, Astrocyte–leucocyte interactions and the mechanisms regulating matrix degradation in CNS tuberculosis

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Matrix metalloproteinases: useful and deleterious

E. Ganea; M. Trifan; A.C. Laslo; G. Putina; C. Cristescu

Biochem Soc Trans (2007) 35 (4): 689–691.

Abstract

View Articletitled, Matrix metalloproteinases: useful and deleterious

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Brevican and phosphacan expression and localization following transient middle cerebral artery occlusion in the rat

G. Haddock; A.K. Cross; S. Allan; B. Sharrack; J. Callaghan; R.A.D. Bunning; D.J. Buttle; M.N. Woodroofe

Biochem Soc Trans (2007) 35 (4): 692–694.

Abstract

View Articletitled, Brevican and phosphacan expression and localization following transient middle cerebral artery occlusion in the rat

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Regulation of fibroblast migration by tenascin-C

A. Trebaul; E.K. Chan; K.S. Midwood

Biochem Soc Trans (2007) 35 (4): 695–697.

Abstract

View Articletitled, Regulation of fibroblast migration by tenascin-C

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Bone marrow stromal cells promote growth and survival of prostate cancer cells

N.A. Cross; M. Papageorgiou; C.L. Eaton

Biochem Soc Trans (2007) 35 (4): 698–700.

Abstract

View Articletitled, Bone marrow stromal cells promote growth and survival of prostate cancer cells

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Cathepsin K in the bone microenvironment: link between obesity and prostate cancer?

I. Podgorski; B.E. Linebaugh; B.F. Sloane

Biochem Soc Trans (2007) 35 (4): 701–703.

Abstract

View Articletitled, Cathepsin K in the bone microenvironment: link between obesity and prostate cancer?

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Phagocytosis of collagen by fibroblasts and invasive cancer cells is mediated by MT1-MMP

H. Lee; K.L. Sodek; Q. Hwang; T.J. Brown; M. Ringuette; J. Sodek

Biochem Soc Trans (2007) 35 (4): 704–706.

Abstract

View Articletitled, Phagocytosis of collagen by fibroblasts and invasive cancer cells is mediated by MT1-MMP

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Family Resemblances? Ligand Binding and Activation of Family A and B G-Protein-Coupled Receptor

Family Resemblances? Ligand Binding and Activation of Family A and B G-Protein-Coupled Receptors

D.R. Poyner; M. Wheatley

Biochem Soc Trans (2007) 35 (4): 707–708.

Abstract

View Articletitled, Family Resemblances? Ligand Binding and Activation of Family A and B G-Protein-Coupled Receptors

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Structural basis of natural ligand binding and activation of the Class II G-protein-coupled secretin receptor

L.J. Miller; M. Dong; K.G. Harikumar; F. Gao

Biochem Soc Trans (2007) 35 (4): 709–712.

Abstract

View Articletitled, Structural basis of natural ligand binding and activation of the Class II G-protein-coupled secretin receptor

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Peptide binding at the GLP-1 receptor

R. Mann; N. Nasr; D. Hadden; J. Sinfield; F. Abidi; S. Al-Sabah; R. López de Maturana; J. Treece-Birch; A. Willshaw; D. Donnelly

Biochem Soc Trans (2007) 35 (4): 713–716.

Abstract

View Articletitled, Peptide binding at the GLP-1 receptor

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Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors

M. Wheatley; J. Simms; S.R. Hawtin; V.J. Wesley; D. Wootten; M. Conner; Z. Lawson; A.C. Conner; A. Baker; Y. Cashmore; R. Kendrick; R.A. Parslow

Biochem Soc Trans (2007) 35 (4): 717–720.

Abstract

View Articletitled, Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors

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Structural characterization of the parathyroid hormone receptor domains determinant for ligand binding

D.F. Mierke; L. Mao; M. Pellegrini; A. Piserchio; J. Plati; N. Tsomaia

Biochem Soc Trans (2007) 35 (4): 721–723.

Abstract

View Articletitled, Structural characterization of the parathyroid hormone receptor domains determinant for ligand binding

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Molecular mechanisms involved in vasoactive intestinal peptide receptor activation and regulation: current knowledge, similarities to and differences from the A family of G-protein-coupled receptors

I. Langer; P. Robberecht

Biochem Soc Trans (2007) 35 (4): 724–728.

Abstract

View Articletitled, Molecular mechanisms involved in vasoactive intestinal peptide receptor activation and regulation: current knowledge, similarities to and differences from the A family of G-protein-coupled receptors

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Ligand binding and activation of the CGRP receptor

A.C. Conner; J. Simms; J. Barwell; M. Wheatley; D.R. Poyner

Biochem Soc Trans (2007) 35 (4): 729–732.

Abstract

View Articletitled, Ligand binding and activation of the CGRP receptor

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Mechanisms underlying agonist efficacy

P.G. Strange

Biochem Soc Trans (2007) 35 (4): 733–736.

Abstract

View Articletitled, Mechanisms underlying agonist efficacy

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Agonist selectivity in the oxytocin/vasopressin receptor family: new insights and challenges

B. Chini; M. Manning

Biochem Soc Trans (2007) 35 (4): 737–741.

Abstract

View Articletitled, Agonist selectivity in the oxytocin/vasopressin receptor family: new insights and challenges

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Phenotypic classification of mutants: a tool for understanding ligand binding and activation of muscarinic acetylcholine receptors

E.C. Hulme; M.S. Bee; J.A. Goodwin

Biochem Soc Trans (2007) 35 (4): 742–745.

Abstract

View Articletitled, Phenotypic classification of mutants: a tool for understanding ligand binding and activation of muscarinic acetylcholine receptors

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Assessing GPCR activation using protein complementation: a novel technique for HTS

R.M. Eglen

Biochem Soc Trans (2007) 35 (4): 746–748.

Abstract

View Articletitled, Assessing GPCR activation using protein complementation: a novel technique for HTS

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Computational studies of Family A and Family B GPCRs

S. Vohra; S.V. Chintapalli; C.J.R. Illingworth; P.J. Reeves; P.M. Mullineaux; H.S.X. Clark; M.K. Dean; G.J.G. Upton; C.A. Reynolds

Biochem Soc Trans (2007) 35 (4): 749–754.

Abstract

View Articletitled, Computational studies of Family A and Family B GPCRs

Supplementary data

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Unravelling the mechanisms underpinning chemokine receptor activation and blockade by small molecules: a fine line between agonism and antagonism?

E. Wise; J.E. Pease

Biochem Soc Trans (2007) 35 (4): 755–759.

Abstract

View Articletitled, Unravelling the mechanisms underpinning chemokine receptor activation and blockade by small molecules: a fine line between agonism and antagonism?

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Neurotensin receptor type 1: Escherichia coli expression, purification, characterization and biophysical study

P.J. Harding; H. Attrill; S. Ross; J.R. Koeppe; A.N. Kapanidis; A. Watts

Biochem Soc Trans (2007) 35 (4): 760–763.

Abstract

View Articletitled, Neurotensin receptor type 1: Escherichia coli expression, purification, characterization and biophysical study

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Monitoring interactions between G-protein-coupled receptors and β-arrestins

K.D.G. Pfleger; M.B. Dalrymple; J.R. Dromey; K.A. Eidne

Biochem Soc Trans (2007) 35 (4): 764–766.

Abstract

View Articletitled, Monitoring interactions between G-protein-coupled receptors and β-arrestins

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Cell-Penetrating Peptide

The many futures for cell-penetrating peptides: how soon is now?

J. Howl; I.D. Nicholl; S. Jones

Biochem Soc Trans (2007) 35 (4): 767–769.

Abstract

View Articletitled, The many futures for cell-penetrating peptides: how soon is now?

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Applications of cell-penetrating peptides in regulation of gene expression

P. Järver; K. Langel; S. El-Andaloussi; Ü. Langel

Biochem Soc Trans (2007) 35 (4): 770–774.

Abstract

View Articletitled, Applications of cell-penetrating peptides in regulation of gene expression

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Cell-penetrating-peptide-based delivery of oligonucleotides: an overview

R. Abes; A.A. Arzumanov; H.M. Moulton; S. Abes; G.D. Ivanova; P.L. Iversen; M.J. Gait; B. Lebleu

Biochem Soc Trans (2007) 35 (4): 775–779.

Abstract

View Articletitled, Cell-penetrating-peptide-based delivery of oligonucleotides: an overview

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Tumour-homing peptides: tools for targeting, imaging and destruction

J. Enbäck; P. Laakkonen

Biochem Soc Trans (2007) 35 (4): 780–783.

Abstract

View Articletitled, Tumour-homing peptides: tools for targeting, imaging and destruction

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Arginine-rich peptides and their internalization mechanisms

S. Futaki; I. Nakase; A. Tadokoro; T. Takeuchi; A.T. Jones

Biochem Soc Trans (2007) 35 (4): 784–787.

Abstract

View Articletitled, Arginine-rich peptides and their internalization mechanisms

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Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells

G.M.K. Poon; J. Gariépy

Biochem Soc Trans (2007) 35 (4): 788–793.

Abstract

View Articletitled, Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells

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all-D proline-rich cell-penetrating peptides: a preliminary in vivo internalization study

S. Pujals; E. Sabidó; T. Tarragó; E. Giralt

Biochem Soc Trans (2007) 35 (4): 794–796.

Abstract

View Articletitled, all-D proline-rich cell-penetrating peptides: a preliminary in vivo internalization study

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Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides

J.A. Gomez; V. Gama; T. Yoshida; W. Sun; P. Hayes; K. Leskov; D. Boothman; S. Matsuyama

Biochem Soc Trans (2007) 35 (4): 797–801.

Abstract

View Articletitled, Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides

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Targeting aggressive B-cell lymphomas with cell-penetrating peptides

A. Melnick

Biochem Soc Trans (2007) 35 (4): 802–806.

Abstract

View Articletitled, Targeting aggressive B-cell lymphomas with cell-penetrating peptides

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Cell-penetrating-peptide-mediated siRNA lung delivery

S.A. Moschos; A.E. Williams; M.A. Lindsay

Biochem Soc Trans (2007) 35 (4): 807–810.

Abstract

View Articletitled, Cell-penetrating-peptide-mediated siRNA lung delivery

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Protein transduction: identification, characterization and optimization

J. Tilstra; K.K. Rehman; T. Hennon; S.E. Plevy; P. Clemens; P.D. Robbins

Biochem Soc Trans (2007) 35 (4): 811–815.

Abstract

View Articletitled, Protein transduction: identification, characterization and optimization

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Tatp-mediated intracellular delivery of pharmaceutical nanocarriers

V.P. Torchilin

Biochem Soc Trans (2007) 35 (4): 816–820.

Abstract

View Articletitled, Tatp-mediated intracellular delivery of pharmaceutical nanocarriers

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Cell-penetrating peptides in drug development: enabling intracellular targets

L. Chen; S.D. Harrison

Biochem Soc Trans (2007) 35 (4): 821–825.

Abstract

View Articletitled, Cell-penetrating peptides in drug development: enabling intracellular targets

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Cell-penetrating peptide–morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo

H.M. Moulton; S. Fletcher; B.W. Neuman; G. McClorey; D.A. Stein; S. Abes; S.D. Wilton; M.J. Buchmeier; B. Lebleu; P.L. Iversen

Biochem Soc Trans (2007) 35 (4): 826–828.

Abstract

View Articletitled, Cell-penetrating peptide–morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo

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Generation, application and quantification of clamp–BioShuttle carriers for plasmid delivery into nuclei of prostate cancer cells

R. Pipkorn; W. Waldeck; J.W. Jenne; B. Didinger; K. Braun

Biochem Soc Trans (2007) 35 (4): 829–832.

Abstract

View Articletitled, Generation, application and quantification of clamp–BioShuttle carriers for plasmid delivery into nuclei of prostate cancer cells

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Targeting the MHC II presentation pathway in allergy vaccine development

C. Rhyner; T. Kündig; C.A. Akdis; R. Crameri

Biochem Soc Trans (2007) 35 (4): 833–834.

Abstract

View Articletitled, Targeting the MHC II presentation pathway in allergy vaccine development

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Biochemical Society Focused Meetings

Matrix Turnover: Mechanisms and Common Denominator

Family Resemblances? Ligand Binding and Activation of Family A and B G-Protein-Coupled Receptor

Cell-Penetrating Peptide

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