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December 2018
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Close ModalDysfunctional cytoskeleton and neurodegeneration: novel pathways in Parkinson's disease? This image represents the degeneration of the neuronal tree during the aging process. In this issue Civiero et al. discuss the consequence of impaired cytoskeletal dynamics on neurite morphology and neuronal physiology in Parkinson's disease. For further details see pages 1653–1663.
ISSN 0300-5127
EISSN 1470-8752
In this Issue
Review Articles
Structural snapshots of RAF kinase interactions
Soheila Rezaei Adariani; Marcel Buchholzer; Mohammad Akbarzadeh; Saeideh Nakhaei-Rad; Radovan Dvorsky; Mohammad Reza Ahmadian
Biochem Soc Trans (2018) 46 (6): 1393–1406.
Structural studies of the spliceosome: past, present and future perspectives
Biochem Soc Trans (2018) 46 (6): 1407–1422.
Regulation of ATP-dependent chromatin remodelers: accelerators/brakes, anchors and sensors
Biochem Soc Trans (2018) 46 (6): 1423–1430.
Recent insights into lytic polysaccharide monooxygenases (LPMOs)
Biochem Soc Trans (2018) 46 (6): 1431–1447.
The role of the interleukin (IL)-6/IL-6 receptor axis in cancer
Biochem Soc Trans (2018) 46 (6): 1449–1462.
Photoreceptor actin dysregulation in syndromic and non-syndromic retinitis pigmentosa
Biochem Soc Trans (2018) 46 (6): 1463–1473.
Substrate polyspecificity and conformational relevance in ABC transporters: new insights from structural studies
Biochem Soc Trans (2018) 46 (6): 1475–1484.
ABCG2: does resolving its structure elucidate the mechanism?
Biochem Soc Trans (2018) 46 (6): 1485–1494.
Membrane protein nanoparticles: the shape of things to come
Biochem Soc Trans (2018) 46 (6): 1495–1504.
Therapeutic strategies to target microbial protein–glycosaminoglycan interactions
Biochem Soc Trans (2018) 46 (6): 1505–1515.
Ribosomal flavours: an acquired taste for specific mRNAs?
Biochem Soc Trans (2018) 46 (6): 1529–1539.
Next-generation flexible formats of VNAR domains expand the drug platform's utility and developability
Obinna C. Ubah; Magdalena J. Buschhaus; Laura Ferguson; Marina Kovaleva; John Steven; Andrew J. Porter; Caroline J. Barelle
Biochem Soc Trans (2018) 46 (6): 1559–1565.
Comparisons of voltage-gated sodium channel structures with open and closed gates and implications for state-dependent drug design
Biochem Soc Trans (2018) 46 (6): 1567–1575.
Specificity and selectivity in post-translational biotin addition
Biochem Soc Trans (2018) 46 (6): 1577–1591.
Metallocluster transactions: dynamic protein interactions guide the biosynthesis of Fe–S clusters in bacteria
Biochem Soc Trans (2018) 46 (6): 1593–1603.
Phage-based biocontrol strategies and their application in agriculture and aquaculture
Biochem Soc Trans (2018) 46 (6): 1605–1613.
‘Stop’ in protein synthesis is modulated with exquisite subtlety by an extended RNA translation signal
Biochem Soc Trans (2018) 46 (6): 1615–1625.
Characterisation of sensor kinase by CD spectroscopy: golden rules and tips
Biochem Soc Trans (2018) 46 (6): 1627–1642.
A tough row to hoe: when replication forks encounter DNA damage
Biochem Soc Trans (2018) 46 (6): 1643–1651.
The precise molecular signals that control endothelial cell–cell adhesion within the vessel wall
Biochem Soc Trans (2018) 46 (6): 1673–1680.
PARPs in genome stability and signal transduction: implications for cancer therapy
Biochem Soc Trans (2018) 46 (6): 1681–1695.
Functional and behavioral consequences of Parkinson's disease-associated LRRK2-G2019S mutation
Biochem Soc Trans (2018) 46 (6): 1697–1705.
PseudoGTPase domains in p190RhoGAP proteins: a mini-review
Biochem Soc Trans (2018) 46 (6): 1713–1720.
New insights into the adaptive transcriptional response to nitrogen starvation in Escherichia coli
Biochem Soc Trans (2018) 46 (6): 1721–1728.
The regulatory role of the kinase-homology domain in receptor guanylyl cyclases: nothing ‘pseudo’ about it!
Biochem Soc Trans (2018) 46 (6): 1729–1742.
Calcium and Ca2+/Calmodulin-dependent kinase II as targets for helminth parasite control
Biochem Soc Trans (2018) 46 (6): 1743–1751.
Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting
Biochem Soc Trans (2018) 46 (6): 1753–1770.
Corrections
Correction: Fine details in complex environments: the power of cryo-electron tomography
Biochem Soc Trans (2018) 46 (6): 1771.
