Substrate polyspecificity and conformational relevance in ABC transporters: new insights from structural studies
Comparisons of voltage-gated sodium channel structures with open and closed gates and implications for state-dependent drug design
Metallocluster transactions: dynamic protein interactions guide the biosynthesis of Fe–S clusters in bacteria
‘Stop’ in protein synthesis is modulated with exquisite subtlety by an extended RNA translation signal
The regulatory role of the kinase-homology domain in receptor guanylyl cyclases: nothing ‘pseudo’ about it!
Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting
Dysfunctional cytoskeleton and neurodegeneration: novel pathways in Parkinson's disease? This image represents the degeneration of the neuronal tree during the aging process. In this issue Civiero et al. discuss the consequence of impaired cytoskeletal dynamics on neurite morphology and neuronal physiology in Parkinson's disease. For further details see pages 1653–1663.