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Issues
December 2020
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Cover Image
Cover Image
The plasma membrane of lymphocytes is highly compartmentalized in so-called nanodomains or protein islands. Proteins such as Caveolin-1 (pink), tetraspanins (blue) or flotillins (violet) define these protein islands and thereby regulate the functioning of the immune system. In this issue (see pages 2387–2397), Schaffer and Minguet discuss the importance of these protein islands regarding lymphocyte activation and the development of immunopathologies. This cover artwork has been created by Susana Minguet.
ISSN 0300-5127
EISSN 1470-8752
In this Issue
Review Articles
Turning the Mre11/Rad50 DNA repair complex on its head: lessons from SMC protein hinges, dynamic coiled-coil movements and DNA loop-extrusion?
Biochem Soc Trans (2020) 48 (6): 2359–2376.
Caveolin-1, tetraspanin CD81 and flotillins in lymphocyte cell membrane organization, signaling and immunopathology
Biochem Soc Trans (2020) 48 (6): 2387–2397.
Decoding co-/post-transcriptional complexities of plant transcriptomes and epitranscriptome using next-generation sequencing technologies
Biochem Soc Trans (2020) 48 (6): 2399–2414.
Varicella-zoster virus: molecular controls of cell fusion-dependent pathogenesis
Biochem Soc Trans (2020) 48 (6): 2415–2435.
Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis
Biochem Soc Trans (2020) 48 (6): 2437–2455.
New perspectives of the cardiac cellular landscape: mapping cellular mediators of cardiac fibrosis using single-cell transcriptomics
Biochem Soc Trans (2020) 48 (6): 2483–2493.
The impact of photorespiration on plant primary metabolism through metabolic and redox regulation
Biochem Soc Trans (2020) 48 (6): 2495–2504.
Membrane protein crystallography in the era of modern structural biology
Biochem Soc Trans (2020) 48 (6): 2505–2524.
The development of proteinase-activated receptor-2 modulators and the challenges involved
Biochem Soc Trans (2020) 48 (6): 2525–2537.
The role of extracellular matrix in tumour angiogenesis: the throne has NOx servants
Biochem Soc Trans (2020) 48 (6): 2539–2555.
Post-transcriptional control of mitochondrial protein composition in changing environmental conditions
Biochem Soc Trans (2020) 48 (6): 2565–2578.
Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases
Biochem Soc Trans (2020) 48 (6): 2615–2624.
A pocket guide on how to structure SARS-CoV-2 drugs and therapies
Biochem Soc Trans (2020) 48 (6): 2625–2641.
Engineering with NanoLuc: a playground for the development of bioluminescent protein switches and sensors
Biochem Soc Trans (2020) 48 (6): 2643–2655.
Fluorescent proteins for in vivo imaging, where's the biliverdin?
Biochem Soc Trans (2020) 48 (6): 2657–2667.
Intrinsically disordered proteins and membranes: a marriage of convenience for cell signalling?
Biochem Soc Trans (2020) 48 (6): 2669–2689.
Mechanisms and consequences of dysregulation of the Tiam family of Rac activators in disease
Biochem Soc Trans (2020) 48 (6): 2703–2719.
Protein–membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies
Biochem Soc Trans (2020) 48 (6): 2721–2728.
Exploiting teeth as a model to study basic features of signaling pathways
Biochem Soc Trans (2020) 48 (6): 2729–2742.
Multifaceted roles of long non-coding RNAs in triple-negative breast cancer: biology and clinical applications
Biochem Soc Trans (2020) 48 (6): 2791–2810.
Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells
Biochem Soc Trans (2020) 48 (6): 2839–2850.
Serological antibody testing in the COVID-19 pandemic: their molecular basis and applications
Biochem Soc Trans (2020) 48 (6): 2851–2863.
Solar-driven water-splitting provides a solution to the energy problem underpinning climate change
Biochem Soc Trans (2020) 48 (6): 2865–2874.
The emerging roles of semaphorin4D/CD100 in immunological diseases
Biochem Soc Trans (2020) 48 (6): 2875–2890.
Keeping your options open: insights from Dppa2/4 into how epigenetic priming factors promote cell plasticity
Biochem Soc Trans (2020) 48 (6): 2891–2902.
Biofilm and swarming emergent behaviours controlled through the aid of biophysical understanding and tools
Biochem Soc Trans (2020) 48 (6): 2903–2913.
Speaker Review
Connecting the dots: combined control of endocytic recycling and degradation
Biochem Soc Trans (2020) 48 (6): 2377–2386.