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Issues
February 2023
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Cover Image
Cover Image
Macrophages are innate immune cells responsible for a variety of tissue-specific homeostatic functions and responding to infiltrating pathogens. A lot of what we know about macrophages comes from studies on unphysiological 2D plastic dishes, however new insights into macrophage biology are emerging thanks to 3D cell culture technology (see the review in this issue by Cutter et al., pages 387–401). Depicted here is a macrophage suspended within a neon 3D dimension. Image provided by Katrina Binger.
ISSN 0300-5127
EISSN 1470-8752
In this Issue
Review Articles
Computational approaches to understand transcription regulation in development
Biochem Soc Trans (2023) 51 (1): 1–12.
Mitochondrial dynamics in macrophages: divide to conquer or unite to survive?
Syeda Farhana Afroz; Karoline D. Raven; Grace M.E.P. Lawrence; Ronan Kapetanovic; Kate Schroder; Matthew J. Sweet
Biochem Soc Trans (2023) 51 (1): 41–56.
Therapeutic targeting of TRAIL death receptors
Francesca Di Cristofano; Andrew George; Vida Tajiknia; Maryam Ghandali; Laura Wu; Yiqun Zhang; Praveen Srinivasan; Jillian Strandberg; Marina Hahn; Ashley Sanchez Sevilla Uruchurtu; Attila A. Seyhan; Benedito A. Carneiro; Lanlan Zhou; Kelsey E. Huntington; Wafik S. El-Deiry
Biochem Soc Trans (2023) 51 (1): 57–70.
Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM
Biochem Soc Trans (2023) 51 (1): 87–99.
The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder
Biochem Soc Trans (2023) 51 (1): 125–135.
The interactions of amyloid β aggregates with phospholipid membranes and the implications for neurodegeneration
Biochem Soc Trans (2023) 51 (1): 147–159.
Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery
Biochem Soc Trans (2023) 51 (1): 195–206.
Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology
Biochem Soc Trans (2023) 51 (1): 275–285.
Towards using 3D cellular cultures to model the activation and diverse functions of macrophages
Biochem Soc Trans (2023) 51 (1): 387–401.
Eliminating oncogenic RAS: back to the future at the drawing board
Biochem Soc Trans (2023) 51 (1): 447–456.