Skip Nav Destination
Issues
October 2024
-
Cover Image
Cover Image
SARS-CoV-2 viral particles have been shown to undergo polyubiquitination by host human E3 ligases. Ubiquitination can have numerous effects on infection, including downregulation of viral proteins and suppression of new virion synthesis or it can result in the dampening of the host immune response and the promotion of viral proliferation. The cover image is an abstract artistic representation of this process, with SARS-CoV-2 (green) being conjugated with ubiquitin (brown) by an E3 ligase (orange). For further information, see the review in this issue by Pellman and colleagues, pages 2009–2021. Cover art created by Jesse Pellman.
ISSN 0300-5127
EISSN 1470-8752
In this Issue
Review Articles
Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection
Biochem Soc Trans (2024) 52 (5): 2009–2021.
Suppression of double-stranded RNA sensing in cancer: molecular mechanisms and therapeutic potential
Biochem Soc Trans (2024) 52 (5): 2035–2045.
Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders
Biochem Soc Trans (2024) 52 (5): 2047–2058.
Using human disease mutations to understand de novo DNA methyltransferase function
Biochem Soc Trans (2024) 52 (5): 2059–2075.
Structural insights into the membrane-bound proteolytic machinery of bacterial protein quality control
Biochem Soc Trans (2024) 52 (5): 2077–2086.
The mRNA dynamics underpinning translational control mechanisms of Drosophila melanogaster oogenesis
Biochem Soc Trans (2024) 52 (5): 2087–2099.
Phase separation and viral factories: unveiling the physical processes supporting RNA packaging in dsRNA viruses
Biochem Soc Trans (2024) 52 (5): 2101–2112.
The dynamic regulatory network of phosphatidic acid metabolism: a spotlight on substrate cycling between phosphatidic acid and diacylglycerol
Biochem Soc Trans (2024) 52 (5): 2123–2132.
Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction
Biochem Soc Trans (2024) 52 (5): 2133–2144.
Biogenesis of omegasomes and autophagosomes in mammalian autophagy
Biochem Soc Trans (2024) 52 (5): 2145–2155.
The role of prokaryotic argonautes in resistance to type II topoisomerases poison ciprofloxacin
Alina Galivondzhyan; Dmitry Sutormin; Vladimir Panteleev; Andrey Kulbachinskiy; Konstantin Severinov
Biochem Soc Trans (2024) 52 (5): 2157–2166.
Voltage-clamp fluorometry for advancing mechanistic understanding of ion channel mechanisms with a focus on acid-sensing ion channels
Biochem Soc Trans (2024) 52 (5): 2167–2177.
Hetero-oligomeric interaction as a new regulatory mechanism for protein arginine methyltransferases
Biochem Soc Trans (2024) 52 (5): 2193–2201.
Understanding the role of ten-eleven translocation family proteins in kidney diseases
Biochem Soc Trans (2024) 52 (5): 2203–2214.