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BRIAN G. LAKE
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Articles

Hepatic peroxisome proliferation and oxidative stress

BRIAN G. LAKE, J. B. GRAY. TIM, ANDREW G. SMITH, JOHN G. EVANS
Journal: Biochemical Society Transactions
Biochem Soc Trans (1990) 18 (1): 94–97.
https://doi.org/10.1042/bst0180094
Published: 01 February 1990
View articletitled, Hepatic peroxisome proliferation and oxidative stress
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Articles

Species differences in hepatic peroxisome proliferation

BRIAN G. LAKE, TIM J. B. GRAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (5): 859–861.
https://doi.org/10.1042/bst0130859
Published: 01 October 1985
View articletitled, Species differences in hepatic peroxisome proliferation
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Articles

Studies on the induction of hepatic xenobiotic metabolism in the guinea pig

BRIAN G. LAKE, MICHAEL A. COLLINS, ROSALYN A. HARRIS, COLIN R. STUBBERFIELD, PAOLO CACIOLA, SHARAT D. GANGOLLI
Journal: Biochemical Society Transactions
Biochem Soc Trans (1980) 8 (1): 95–96.
https://doi.org/10.1042/bst0080095
Published: 01 February 1980
View articletitled, Studies on the induction of hepatic xenobiotic metabolism in the guinea pig
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Articles

Studies on the hepatotoxicity and metabolism of coumarin in the rat

BRIAN G. LAKE, MICHAEL A. COLLINS, ROSALYN A. HARRIS, JOHN C. PHILLIPS, JOHN G. EVANS, SHARAT D. GANGOLLI
Journal: Biochemical Society Transactions
Biochem Soc Trans (1980) 8 (1): 96–97.
https://doi.org/10.1042/bst0080096
Published: 01 February 1980
View articletitled, Studies on the hepatotoxicity and metabolism of coumarin in the rat
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Articles

The Effect of 4-Hydroxybiphenyl and 2-Naphthol on Hepatic Xenobiotic Metabolism and the Urinary Excretion of Metabolites of the d-Glucuronic Acid Pathway in the Rat

BRIAN G. LAKE, RONALD C. LONGLAND, IRENE A. HEROD, MICHAEL A. COLLINS, SHARAT D. GANGOLLI
Journal: Biochemical Society Transactions
Biochem Soc Trans (1978) 6 (6): 1246–1248.
https://doi.org/10.1042/bst0061246
Published: 01 December 1978
View articletitled, The Effect of 4-Hydroxybiphenyl and 2-Naphthol on Hepatic Xenobiotic Metabolism and the Urinary Excretion of Metabolites of the d-Glucuronic Acid Pathway in the Rat
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Articles

The Effect of Treatment with a Polychlorinated-Biphenyl Mixture on Hepatic and Extrahepatic Xenobiotic Metabolism in the Rat and Ferret

BRIAN G. LAKE, MICHAEL A. COLLINS, SHARAT D. GANGOLLI
Journal: Biochemical Society Transactions
Biochem Soc Trans (1978) 6 (6): 1251–1252.
https://doi.org/10.1042/bst0061251
Published: 01 December 1978
View articletitled, The Effect of Treatment with a Polychlorinated-Biphenyl Mixture on Hepatic and Extrahepatic Xenobiotic Metabolism in the Rat and Ferret
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Articles

Further Studies of the Metabolism of N -Nitroso[2,5- 14 C]pyrrolidine in the Rat

RICHARD C. COTTRELL, DAVID G. WALTERS, PHILIP J. YOUNG, BRIAN G. LAKE, JOHN C. PHILLIPS, SHARAT D. GANGOLLI
Journal: Biochemical Society Transactions
Biochem Soc Trans (1978) 6 (5): 959.
https://doi.org/10.1042/bst0060959
Published: 01 October 1978
View articletitled, Further Studies of the Metabolism of N -Nitroso[2,5- 14 C]pyrrolidine in the Rat
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Articles

The Effect of Repeated Administration on Allyl Alcohol-Induced Hepatotoxicity in the Rat

BRIAN G. LAKE, SHARAT D. GANGOLLI, MALCOLM G. WRIGHT PAUL GRASSO, FRANCIS M. B. CARPANINI, KENNETH R. BUTTERWORTH
Journal: Biochemical Society Transactions
Biochem Soc Trans (1978) 6 (1): 145–147.
https://doi.org/10.1042/bst0060145
Published: 01 February 1978
View articletitled, The Effect of Repeated Administration on Allyl Alcohol-Induced Hepatotoxicity in the Rat
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Articles

Preliminary Studies of the Metabolism of N -Nitroso[2,5- 14 C]pyrrolidine in the Rat

RICHARD C. COTTRELL, PHILIP J. YOUNG, IRENE A. HEROD, BRIAN G. LAKE, JOHN C. PHILLIPS, SHARAT D. GANGOLLI
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (4): 1011–1013.
https://doi.org/10.1042/bst0051011
Published: 01 August 1977
View articletitled, Preliminary Studies of the Metabolism of N -Nitroso[2,5- 14 C]pyrrolidine in the Rat
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Articles

Further Studies on the Metabolism of Dimethylnitrosamine by Rat Liver in vitro

BRIAN G. LAKE, RICHARD C. COTTRELL, JOHN C. PHILLIPS, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (4): 1013–1015.
https://doi.org/10.1042/bst0051013
Published: 01 August 1977
View articletitled, Further Studies on the Metabolism of Dimethylnitrosamine by Rat Liver in vitro
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Articles

The Effect of Some Foreign Compounds on Hepatic Xenobiotic Metabolism and on the Urinary Excretion of d-Glucuronic Acid Metabolites in the Rat

BRIAN G. LAKE, RONALD C. LONGLAND, ROSALYN A. HODGSON, BRIAN J. SEVERN, SHARAT D. GANGOLLI
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (1): 308–309.
https://doi.org/10.1042/bst0050308
Published: 01 February 1977
View articletitled, The Effect of Some Foreign Compounds on Hepatic Xenobiotic Metabolism and on the Urinary Excretion of d-Glucuronic Acid Metabolites in the Rat
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Articles

The Hepatic Effects of Orally Administered Di-(2-ethylhexyl) Phthalate in the Ferret

BRIAN G. LAKE, PAUL G. BRANTOM, SHARAT D. GANGOLLI, KENNETH R. BUTTERWORTH, PAUL GRASSO, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (1): 310–311.
https://doi.org/10.1042/bst0050310
Published: 01 February 1977
View articletitled, The Hepatic Effects of Orally Administered Di-(2-ethylhexyl) Phthalate in the Ferret
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Articles

Metabolie Degradation of Stable-Isotope-Labelled Dimethylnitrosamine by Rat Liver

RICHARD C. COTTRELL, BRIAN G. LAKE, JOHN C. PHILLIPS, SHARAT D. GANGOLLI
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (1): 311–312.
https://doi.org/10.1042/bst0050311
Published: 01 February 1977
View articletitled, Metabolie Degradation of Stable-Isotope-Labelled Dimethylnitrosamine by Rat Liver
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Articles

Further Studies on the Inhibition of Rat Hepatic Dimethylnitrosamine Metabolism in vitro

BRIAN G. LAKE, JOHN C. PHILLIPS, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1976) 4 (4): 684–685.
https://doi.org/10.1042/bst0040684
Published: 01 August 1976
View articletitled, Further Studies on the Inhibition of Rat Hepatic Dimethylnitrosamine Metabolism in vitro
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Articles

Studies on the Hydrolysis in vitro of Phthalate Esters by Hepatic and Intestinal Mucosal Preparations from Various Species

BRIAN G. LAKE, JOHN C. PHILLIPS, ROSALYN A. HODGSON, BRIAN J. SEVERN, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1976) 4 (4): 654–655.
https://doi.org/10.1042/bst0040654
Published: 01 August 1976
View articletitled, Studies on the Hydrolysis in vitro of Phthalate Esters by Hepatic and Intestinal Mucosal Preparations from Various Species
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Articles

The Influence of Various Compounds in vitro on the Hepatic Microsomal Metabolism of DimethyInitrosamine in the Rat

BRIAN G. LAKE, MARGARET J. MINSKI, JOHN C. PHILLIPS, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1975) 3 (6): 959–961.
https://doi.org/10.1042/bst0030959
Published: 01 December 1975
View articletitled, The Influence of Various Compounds in vitro on the Hepatic Microsomal Metabolism of DimethyInitrosamine in the Rat
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Articles

Studies on the Role of Cytosol in the Hepatic Metabolism of Dimethylnitrosamine

BRIAN G. LAKE, MARGARET J. MINSKI, JOHN C. PHILLIPS, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1975) 3 (2): 287–290.
https://doi.org/10.1042/bst0030287
Published: 01 April 1975
View articletitled, Studies on the Role of Cytosol in the Hepatic Metabolism of Dimethylnitrosamine
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Articles

Studies on the Metabolism of Diethylnitrosamine in the Rat

JOHN C. PHILLIPS, BRIAN G. LAKE, MARGARET J. MINSKI, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1975) 3 (2): 285–287.
https://doi.org/10.1042/bst0030285
Published: 01 April 1975
View articletitled, Studies on the Metabolism of Diethylnitrosamine in the Rat
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Articles

Further Studies on the Effects of Inhibitors on the Metabolism and Toxicity of Dimethylnitrosamine

JOHN C. PHILLIPS, CHRISTINE E. HEADING, BRIAN G. LAKE, SHARAT D. GANGOLLI, PAUL GRASSO, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1975) 3 (1): 179–183.
https://doi.org/10.1042/bst0030179
Published: 01 February 1975
View articletitled, Further Studies on the Effects of Inhibitors on the Metabolism and Toxicity of Dimethylnitrosamine
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Articles

Comparative Studies on Hepatic Dimethylnitrosamine Demethylase and some Xenobiotic-Metabolizing Enzymes in the Rat

BRIAN G. LAKE, MARGARET J. MINSKI, JOHN C. PHILLIPS, CHRISTINE E. HEADING, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1975) 3 (1): 183–185.
https://doi.org/10.1042/bst0030183
Published: 01 February 1975
View articletitled, Comparative Studies on Hepatic Dimethylnitrosamine Demethylase and some Xenobiotic-Metabolizing Enzymes in the Rat
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Articles

The Effect of some Inducers of Hepatic Xenobiotic-Metabolizing Enzymes on the Urinary Excretion of d-Glucuronic Acid Metabolites in the Rat

BRIAN G. LAKE, RONALD C. LONGLAND, ROSALYN A. HODGSON, BRIAN J. SEVERN, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1975) 3 (1): 188–191.
https://doi.org/10.1042/bst0030188
Published: 01 February 1975
View articletitled, The Effect of some Inducers of Hepatic Xenobiotic-Metabolizing Enzymes on the Urinary Excretion of d-Glucuronic Acid Metabolites in the Rat
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Articles

Studies on the Effects of Phenobarbitone and 20-Methylcholanthrene Pretreatments on the Metabolism and Toxicity of Dimethylnitrosamine in the Rat

BRIAN G. LAKE, CHRISTINE E. HEADING, JOHN C. PHILLIPS, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1974) 2 (5): 882–885.
https://doi.org/10.1042/bst0020882
Published: 01 October 1974
View articletitled, Studies on the Effects of Phenobarbitone and 20-Methylcholanthrene Pretreatments on the Metabolism and Toxicity of Dimethylnitrosamine in the Rat
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Articles

Studies in vivo on the Inhibition of Dimethylnitrosamine Metabolism in the Rat

JOHN C. PHILLIPS, CHRISTINE E. HEADING, BRIAN G. LAKE, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1974) 2 (5): 885–888.
https://doi.org/10.1042/bst0020885
Published: 01 October 1974
View articletitled, Studies in vivo on the Inhibition of Dimethylnitrosamine Metabolism in the Rat
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Articles

Some Aspects of the Metabolism of Dimethylnitrosamine in the Rat

CHRISTINE E. HEADING, JOHN C. PHILLIPS, BRIAN G. LAKE, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1974) 2 (4): 607–610.
https://doi.org/10.1042/bst0020607
Published: 01 August 1974
View articletitled, Some Aspects of the Metabolism of Dimethylnitrosamine in the Rat
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Articles

Some Studies on the Metabolism in vitro of Dimethylnitrosamine by Rat Liver

BRIAN G. LAKE, CHRISTINE E. HEADING, JOHN C. PHILLIPS, SHARAT D. GANGOLLI, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1974) 2 (4): 610–612.
https://doi.org/10.1042/bst0020610
Published: 01 August 1974
View articletitled, Some Studies on the Metabolism in vitro of Dimethylnitrosamine by Rat Liver
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Articles

Studies on the Effects of the Oral Administration of Di-(2-ethylhexyl)-phthalate on Some Hepatic Enzymes in the Rat

BRIAN G. LAKE, SHARAT D. GANGOLLI, MALCOLM G. WRIGHT, PAUL GRASSO, ALUN G. LLOYD
Journal: Biochemical Society Transactions
Biochem Soc Trans (1974) 2 (2): 322–325.
https://doi.org/10.1042/bst0020322
Published: 01 April 1974
View articletitled, Studies on the Effects of the Oral Administration of Di-(2-ethylhexyl)-phthalate on Some Hepatic Enzymes in the Rat
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