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D. GRAHAME HARDIE
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Articles

AMPK: a cellular energy sensor primarily regulated by AMP

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Graeme J. Gowans, D. Grahame Hardie
Journal: Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 71–75.
https://doi.org/10.1042/BST20130244
Published: 23 January 2014
View articletitled, AMPK: a cellular energy sensor primarily regulated by AMP
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Articles

AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

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Madhumita Dandapani, D. Grahame Hardie
Journal: Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (2): 687–693.
https://doi.org/10.1042/BST20120351
Published: 21 March 2013
View articletitled, AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
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Articles

AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer

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D. Grahame Hardie
Journal: Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (1): 1–13.
https://doi.org/10.1042/BST0390001
Published: 19 January 2011
View articletitled, AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer
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Articles

Cell-wide analysis of secretory granule dynamics in three dimensions in living pancreatic β-cells: evidence against a role for AMPK-dependent phosphorylation of KLC1 at Ser 517 /Ser 520 in glucose-stimulated insulin granule movement

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Angela McDonald, Sarah Fogarty, Isabelle Leclerc, Elaine V. Hill, D. Grahame Hardie, Guy A. Rutter
Journal: Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (1): 205–208.
https://doi.org/10.1042/BST0380205
Published: 19 January 2010
View articletitled, Cell-wide analysis of secretory granule dynamics in three dimensions in living pancreatic β-cells: evidence against a role for AMPK-dependent phosphorylation of KLC1 at Ser 517 /Ser 520 in glucose-stimulated insulin granule movement
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Articles

β-Ketoacyl-acyl-carrier protein synthase from developing seeds of oilseed rape ( Brassica napus )

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ROBERT W. MACKINTOSH, D. GRAHAME HARDIE, ANTONI R. SLABAS
Journal: Biochemical Society Transactions
Biochem Soc Trans (1989) 17 (4): 686–687.
https://doi.org/10.1042/bst0170686
Published: 01 August 1989
View articletitled, β-Ketoacyl-acyl-carrier protein synthase from developing seeds of oilseed rape ( Brassica napus )
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Articles

Insulin activation of acetyl-CoA carboxylase in isolated mammary acini from lactating rats fed a high-fat diet

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MICHAEL R. MUNDAY, D. GRAHAME HARDIE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (6): 1075–1076.
https://doi.org/10.1042/bst0141075
Published: 01 December 1986
View articletitled, Insulin activation of acetyl-CoA carboxylase in isolated mammary acini from lactating rats fed a high-fat diet
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Articles

Isolation of a cyclic-AMP-independent protein kinase from rat liver and its effect on the enzymic activity of acetyl-CoA carboxylase

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DAVID CARLING, D. GRAHAME HARDIE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (6): 1076–1077.
https://doi.org/10.1042/bst0141076
Published: 01 December 1986
View articletitled, Isolation of a cyclic-AMP-independent protein kinase from rat liver and its effect on the enzymic activity of acetyl-CoA carboxylase
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Articles

Mammalian fatty acid synthase: a chimeric protein which has evolved by gene fusion

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D. GRAHAME HARDIE, ALUN D. McCARTHY, MARTIN BRADDOCK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (3): 568–570.
https://doi.org/10.1042/bst0140568
Published: 01 June 1986
View articletitled, Mammalian fatty acid synthase: a chimeric protein which has evolved by gene fusion
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Articles

The role of phosphorylation/dephosphorylation of acetyl-CoA carboxylase in the regulation of mammalian fatty acid biosynthesis

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MICHAEL R. MUNDAY, TIMOTHY A. J. HAYSTEAD, ROSS HOLLAND, DAVID A. CARLING, D. GRAHAME HARDIE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (3): 559–562.
https://doi.org/10.1042/bst0140559
Published: 01 June 1986
View articletitled, The role of phosphorylation/dephosphorylation of acetyl-CoA carboxylase in the regulation of mammalian fatty acid biosynthesis
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Articles

Lipogenesis and acetyl-CoA carboxylase activity in lactating rat mammary gland: stimulation by spermine

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MICHAEL R. MUNDAY, D. GRAHAME HARDIE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (5): 882–883.
https://doi.org/10.1042/bst0130882
Published: 01 October 1985
View articletitled, Lipogenesis and acetyl-CoA carboxylase activity in lactating rat mammary gland: stimulation by spermine
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Articles

Fatty acid synthase: probing the structure of a multifunctional protein by limited proteolysis

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D. GRAHAME HARDIE, ALUN D. McCARTHY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (2): 297–299.
https://doi.org/10.1042/bst0130297
Published: 01 April 1985
View articletitled, Fatty acid synthase: probing the structure of a multifunctional protein by limited proteolysis
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Articles

ISOLATION OF TWO CYCLIC AMP-INDEPENDENT PROTEIN KINASES WHICH PHOSPHORYLATE ACETYL-COA CARBOXYLASE

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D. Grahame Hardie
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (2): 237P.
https://doi.org/10.1042/bst009237pb
Published: 01 April 1981
View articletitled, ISOLATION OF TWO CYCLIC AMP-INDEPENDENT PROTEIN KINASES WHICH PHOSPHORYLATE ACETYL-COA CARBOXYLASE
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Articles

STUDIES OF THE SITE ON ATP-CITRATE LYASE PHOSPHORYLATED BY CYCLIC AMP-DEPENDENT PROTEIN KINASE

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Paul S. Guy, Alastair Aitken, D. Grahame Hardie
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (2): 237P.
https://doi.org/10.1042/bst009237pc
Published: 01 April 1981
View articletitled, STUDIES OF THE SITE ON ATP-CITRATE LYASE PHOSPHORYLATED BY CYCLIC AMP-DEPENDENT PROTEIN KINASE
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Articles

Rapid removal of one of the phosphorylation sites on acetyl-CoA carboxylase by limited proteolysis

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PAUL S. GUY, D. GRAHAME HARDIE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1980) 8 (3): 387–388.
https://doi.org/10.1042/bst0080387a
Published: 01 June 1980
View articletitled, Rapid removal of one of the phosphorylation sites on acetyl-CoA carboxylase by limited proteolysis
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Articles

Regulation of Acetyl-Coenzyme A Carboxylase by Phosphorylation-Dephosphorylation

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D. GRAHAME HARDIE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1979) 7 (1): 228.
https://doi.org/10.1042/bst0070228b
Published: 01 February 1979
View articletitled, Regulation of Acetyl-Coenzyme A Carboxylase by Phosphorylation-Dephosphorylation
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