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J. JOHN HOLBROOK
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Articles

Towards the construction of a universal NAD(P) + -dependent dehydrogenase: comparative and evolutionary considerations

Anthony R. Clarke, Stephen Colebrook, Antonio Cortes, David C. Emery, David J. Halsall, Keith W. Hart, Richard M. Jackson, Helen M. Wilks, J. John Holbrook
Journal: Biochemical Society Transactions
Biochem Soc Trans (1991) 19 (3): 576–581.
DOI: https://doi.org/10.1042/bst0190576
Published: 01 August 1991
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Substrate-binding to lactate dehydrogenase perturbs an intersubunit equilibrium sensed by engineered tryptophan-248

ADAM D. B. WALDMAN, DAVID A. BARSTOW, ANTHONY A. CLARKE, ENRICO GRATTON, TONY ATKINSON, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (6): 1158–1159.
DOI: https://doi.org/10.1042/bst0151158
Published: 01 December 1987
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Measurement of protein dynamics during lactate dehydrogenase re-folding by protein engineering

ANTHONY A. CLARKE, DAVID A. BARSTOW, ADAM D. B. WALDMAN, HELEN M. WILKS, KEITH W. HART, TONY ATKINSON, DAVID J. S. BIRCH, WILLIAM N. CHIA, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (6): 1147–1148.
DOI: https://doi.org/10.1042/bst0151147
Published: 01 December 1987
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Mapping motion in large proteins by single tryptophan probes inserted by site-directed mutagenesis: lactate dehydrogenase

TONY ATKINSON, DAVID A. BARSTOW, WILLIAM N. CHIA, ANTHONY R. CLARKE, KEITH W. HART, ADAM D. B. WALDMAN, DALE B. WIGLEY, HELEN WILKS, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (5): 991–993.
DOI: https://doi.org/10.1042/bst0150991
Published: 01 October 1987
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Site-directed mutagenesis of Bacillus stearothermophilus lactate dehydrogenase

ANTHONY R. CLARKE, DALE B. WIGLEY, DAVID A. BARSTOW, WILLIAM N. CHIA, ADAM D. B. WALDMAN, KEITH W. HART, TONY ATKINSON, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (1): 152–153.
DOI: https://doi.org/10.1042/bst0150152
Published: 01 February 1987
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Fluorescence polarization studies of the thrombin/anti-thrombin reactions

JOHN R. N. EVINGTON, PETER A. FELDMAN, MOLLIE LUSCOMBE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (4): 773–774.
DOI: https://doi.org/10.1042/bst0130773a
Published: 01 August 1985
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Low-temperature transient kinetic studies of peptide-loop movement in pig heart [Tyr(3NO 2 ) 237 ]lactate dehydrogenase

ADAM D. B. WALDMAN, ANTHONY R. CLARKE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (1): 257.
DOI: https://doi.org/10.1042/bst0130257
Published: 01 February 1985
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Interaction of plasma fibronectin with heparin and heparan sulphate

JOHN R. N. EVINGTON, MOLLIE LUSCOMBE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (1): 243–244.
DOI: https://doi.org/10.1042/bst0130243
Published: 01 February 1985
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The association of apolipoprotein-CII with lipoprotein lipase in the presence and absence of a triglyceride substrate

ANTHONY R. CLARKE, MOLLIE LUSCOMBE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (1): 137–138.
DOI: https://doi.org/10.1042/bst0130137
Published: 01 February 1985
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Multivalent proteins and multidentate polysaccharides: Interaction of platelet factor 4 and heparin

MOLLIE LUSCOMBE, SUSAN E. MARSHALL, DUNCAN S. PEPPER, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (6): 501–502.
DOI: https://doi.org/10.1042/bst0090501
Published: 01 December 1981
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THE ABILITY OF POLYSACCHARIDES TO ASSEMBLE PROTEINS INTO DIFFERENT MACROMOLECULAR COMPLEXES: A STUDY USING POLARIZATION OF FLUORESCENCE

Mollle Luscombe, Susan E. Marshall, J. John Holbrook
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (2): 182P.
DOI: https://doi.org/10.1042/bst009182pb
Published: 01 April 1981
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Calcium and the Assembly of Human Blood-Clotting Factor XIII

PAUL E. BOCK, ANDREW D. BEAVIS, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1979) 7 (4): 627–628.
DOI: https://doi.org/10.1042/bst0070627
Published: 01 August 1979
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Factor XIII: A Study using Polarization of Fluorescence of the Activation of the Enzyme by Calcium and by Substrate

J. JOHN HOLBROOK, BARBARA A. LEWIS, JEAN-MARIE FREYSSINET, PAUL E. BOCK, JOSEPH D. SHORE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (5): 1247–1251.
DOI: https://doi.org/10.1042/bst0051247a
Published: 01 October 1977
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Calcium Ion-Induced Enzyme Dissociation and the Appearance of Enzyme Activity in Human Plasma Factor XIII

RODNEY D. COOKE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1973) 1 (5): 1198–1200.
DOI: https://doi.org/10.1042/bst0011198
Published: 01 September 1973
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