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J. JOHN HOLBROOK
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Articles

Towards the construction of a universal NAD(P) + -dependent dehydrogenase: comparative and evolutionary considerations

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Anthony R. Clarke, Stephen Colebrook, Antonio Cortes, David C. Emery, David J. Halsall, Keith W. Hart, Richard M. Jackson, Helen M. Wilks, J. John Holbrook
Journal: Biochemical Society Transactions
Biochem Soc Trans (1991) 19 (3): 576–581.
https://doi.org/10.1042/bst0190576
Published: 01 August 1991
View articletitled, Towards the construction of a universal NAD(P) + -dependent dehydrogenase: comparative and evolutionary considerations
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Articles

Measurement of protein dynamics during lactate dehydrogenase re-folding by protein engineering

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ANTHONY A. CLARKE, DAVID A. BARSTOW, ADAM D. B. WALDMAN, HELEN M. WILKS, KEITH W. HART, TONY ATKINSON, DAVID J. S. BIRCH, WILLIAM N. CHIA, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (6): 1147–1148.
https://doi.org/10.1042/bst0151147
Published: 01 December 1987
View articletitled, Measurement of protein dynamics during lactate dehydrogenase re-folding by protein engineering
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Articles

Substrate-binding to lactate dehydrogenase perturbs an intersubunit equilibrium sensed by engineered tryptophan-248

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ADAM D. B. WALDMAN, DAVID A. BARSTOW, ANTHONY A. CLARKE, ENRICO GRATTON, TONY ATKINSON, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (6): 1158–1159.
https://doi.org/10.1042/bst0151158
Published: 01 December 1987
View articletitled, Substrate-binding to lactate dehydrogenase perturbs an intersubunit equilibrium sensed by engineered tryptophan-248
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Articles

Mapping motion in large proteins by single tryptophan probes inserted by site-directed mutagenesis: lactate dehydrogenase

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TONY ATKINSON, DAVID A. BARSTOW, WILLIAM N. CHIA, ANTHONY R. CLARKE, KEITH W. HART, ADAM D. B. WALDMAN, DALE B. WIGLEY, HELEN WILKS, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (5): 991–993.
https://doi.org/10.1042/bst0150991
Published: 01 October 1987
View articletitled, Mapping motion in large proteins by single tryptophan probes inserted by site-directed mutagenesis: lactate dehydrogenase
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Articles

Site-directed mutagenesis of Bacillus stearothermophilus lactate dehydrogenase

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ANTHONY R. CLARKE, DALE B. WIGLEY, DAVID A. BARSTOW, WILLIAM N. CHIA, ADAM D. B. WALDMAN, KEITH W. HART, TONY ATKINSON, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (1): 152–153.
https://doi.org/10.1042/bst0150152
Published: 01 February 1987
View articletitled, Site-directed mutagenesis of Bacillus stearothermophilus lactate dehydrogenase
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Articles

Fluorescence polarization studies of the thrombin/anti-thrombin reactions

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JOHN R. N. EVINGTON, PETER A. FELDMAN, MOLLIE LUSCOMBE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (4): 773–774.
https://doi.org/10.1042/bst0130773a
Published: 01 August 1985
View articletitled, Fluorescence polarization studies of the thrombin/anti-thrombin reactions
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Articles

Low-temperature transient kinetic studies of peptide-loop movement in pig heart [Tyr(3NO 2 ) 237 ]lactate dehydrogenase

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ADAM D. B. WALDMAN, ANTHONY R. CLARKE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (1): 257.
https://doi.org/10.1042/bst0130257
Published: 01 February 1985
View articletitled, Low-temperature transient kinetic studies of peptide-loop movement in pig heart [Tyr(3NO 2 ) 237 ]lactate dehydrogenase
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Articles

Interaction of plasma fibronectin with heparin and heparan sulphate

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JOHN R. N. EVINGTON, MOLLIE LUSCOMBE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (1): 243–244.
https://doi.org/10.1042/bst0130243
Published: 01 February 1985
View articletitled, Interaction of plasma fibronectin with heparin and heparan sulphate
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Articles

The association of apolipoprotein-CII with lipoprotein lipase in the presence and absence of a triglyceride substrate

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ANTHONY R. CLARKE, MOLLIE LUSCOMBE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (1): 137–138.
https://doi.org/10.1042/bst0130137
Published: 01 February 1985
View articletitled, The association of apolipoprotein-CII with lipoprotein lipase in the presence and absence of a triglyceride substrate
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Articles

Multivalent proteins and multidentate polysaccharides: Interaction of platelet factor 4 and heparin

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MOLLIE LUSCOMBE, SUSAN E. MARSHALL, DUNCAN S. PEPPER, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (6): 501–502.
https://doi.org/10.1042/bst0090501
Published: 01 December 1981
View articletitled, Multivalent proteins and multidentate polysaccharides: Interaction of platelet factor 4 and heparin
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Articles

THE ABILITY OF POLYSACCHARIDES TO ASSEMBLE PROTEINS INTO DIFFERENT MACROMOLECULAR COMPLEXES: A STUDY USING POLARIZATION OF FLUORESCENCE

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Mollle Luscombe, Susan E. Marshall, J. John Holbrook
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (2): 182P.
https://doi.org/10.1042/bst009182pb
Published: 01 April 1981
View articletitled, THE ABILITY OF POLYSACCHARIDES TO ASSEMBLE PROTEINS INTO DIFFERENT MACROMOLECULAR COMPLEXES: A STUDY USING POLARIZATION OF FLUORESCENCE
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Articles

Calcium and the Assembly of Human Blood-Clotting Factor XIII

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PAUL E. BOCK, ANDREW D. BEAVIS, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1979) 7 (4): 627–628.
https://doi.org/10.1042/bst0070627
Published: 01 August 1979
View articletitled, Calcium and the Assembly of Human Blood-Clotting Factor XIII
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Articles

Factor XIII: A Study using Polarization of Fluorescence of the Activation of the Enzyme by Calcium and by Substrate

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J. JOHN HOLBROOK, BARBARA A. LEWIS, JEAN-MARIE FREYSSINET, PAUL E. BOCK, JOSEPH D. SHORE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (5): 1247–1251.
https://doi.org/10.1042/bst0051247a
Published: 01 October 1977
View articletitled, Factor XIII: A Study using Polarization of Fluorescence of the Activation of the Enzyme by Calcium and by Substrate
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Articles

Calcium Ion-Induced Enzyme Dissociation and the Appearance of Enzyme Activity in Human Plasma Factor XIII

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RODNEY D. COOKE, J. JOHN HOLBROOK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1973) 1 (5): 1198–1200.
https://doi.org/10.1042/bst0011198
Published: 01 September 1973
View articletitled, Calcium Ion-Induced Enzyme Dissociation and the Appearance of Enzyme Activity in Human Plasma Factor XIII
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