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Nigel M. Hooper
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Articles

Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation

Harry Aldworth, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 431–440.
https://doi.org/10.1042/BST20230918
Published: 08 February 2024
View article titled, Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation
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Articles

Mechanism of the metal-mediated endocytosis of the prion protein

Nigel M. Hooper, David R. Taylor, Nicole T. Watt
Journal: Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (6): 1272–1276.
https://doi.org/10.1042/BST0361272
Published: 19 November 2008
View article titled, Mechanism of the metal-mediated endocytosis of the prion protein
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Articles

Role of the transmembrane form of the prion protein in neurodegeneration

Andrew Gillott, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2002) 30 (3): A79.
https://doi.org/10.1042/bst030a079b
Published: 01 June 2002
View article titled, Role of the transmembrane form of the prion protein in neurodegeneration
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Articles

The ectodomain of angiotensin converting enzyme does not dictate sensitivity to secretase cleavage

Susan Pang, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (5): A262.
https://doi.org/10.1042/bst028a262c
Published: 01 October 2000
View article titled, The ectodomain of angiotensin converting enzyme does not dictate sensitivity to secretase cleavage
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Articles

N-terminal anchorage of the prion protein results in a novel proteinase K resistant fragment

Fanning Zeng, Adrian R. Walmsley, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (5): A349.
https://doi.org/10.1042/bst028a349
Published: 01 October 2000
View article titled, N-terminal anchorage of the prion protein results in a novel proteinase K resistant fragment
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Articles

Cloning and characterisation of human cytosolic aminopeptidase P

Graeme S. Cottrell, Nigel M. Hooper, Anthony J. Turner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (3): A84.
https://doi.org/10.1042/bst028a084a
Published: 01 June 2000
View article titled, Cloning and characterisation of human cytosolic aminopeptidase P
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Articles

C-terminal membrane anchorage is required for N -glycosylation of the prion protein

Adrian R. Walmsley, Fanning Zeng, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (3): A80.
https://doi.org/10.1042/bst028a080a
Published: 01 June 2000
View article titled, C-terminal membrane anchorage is required for N -glycosylation of the prion protein
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Articles

The juxtamembrane stalk region of angiotensin converting enzyme confers susceptibility to secretase cleavage

Susan Pang, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (3): A80.
https://doi.org/10.1042/bst028a080b
Published: 01 June 2000
View article titled, The juxtamembrane stalk region of angiotensin converting enzyme confers susceptibility to secretase cleavage
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Articles

Is the proteolytic processing of the prion protein autocatalytic?

W. Sumudhu S. Perera, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (3): A80.
https://doi.org/10.1042/bst028a080c
Published: 01 June 2000
View article titled, Is the proteolytic processing of the prion protein autocatalytic?
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Articles

Role of Cys43 and the C-terminal domain in the structure and function of murine Aminopeptidase A

Lisa Ofner, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (3): A81.
https://doi.org/10.1042/bst028a081
Published: 01 June 2000
View article titled, Role of Cys43 and the C-terminal domain in the structure and function of murine Aminopeptidase A
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Articles

Identification and Characterisation of a Novel Human Zinc Metalloprotease with Homology to Angiotensin Converting Enzyme

Sarah R. Tipnis, Nigel M. Hooper, Anthony J. Turner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (3): A81.
https://doi.org/10.1042/bst028a081b
Published: 01 June 2000
View article titled, Identification and Characterisation of a Novel Human Zinc Metalloprotease with Homology to Angiotensin Converting Enzyme
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Articles

REGULATION OF sAPPα SECRETION BY MUSCARINE IN THE HUMAN NEUROBLASTOMA CELL LINE SH-SY5Y

ROSA M. CANET-AVILES, ANTHONY J. TURNER, NIGEL M. HOOPER, PETER F.T. VAUGHAN
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (1): A33.
https://doi.org/10.1042/bst028a033b
Published: 01 February 2000
View article titled, REGULATION OF sAPPα SECRETION BY MUSCARINE IN THE HUMAN NEUROBLASTOMA CELL LINE SH-SY5Y
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Articles

Role for ADAM-family proteinases as membrane protein secretases

Anthony J. Turner, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (1999) 27 (2): 255–260.
https://doi.org/10.1042/bst0270255
Published: 01 February 1999
View article titled, Role for ADAM-family proteinases as membrane protein secretases
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Articles

A role for ADAMs proteinases as membrane protein secretases

Anthony J. Turner, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (1999) 27 (1): A24.
https://doi.org/10.1042/bst027a024b
Published: 01 February 1999
View article titled, A role for ADAMs proteinases as membrane protein secretases
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Articles

Insulin-Stimulated Release of GPI-Anchored Proteins

Susan Pang, Sara Movahedi, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (1999) 27 (1): A54.
https://doi.org/10.1042/bst027a054
Published: 01 February 1999
View article titled, Insulin-Stimulated Release of GPI-Anchored Proteins
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Articles

Proteolytic Fragmentation of Aminopeptidase N

Lisa D. Other, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (1999) 27 (1): A54.
https://doi.org/10.1042/bst027a054a
Published: 01 February 1999
View article titled, Proteolytic Fragmentation of Aminopeptidase N
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Articles

Detergent Solubility and Proteolytic Processing of the Prion Protein

Adrian R. Walmsley, Fanning Zeng, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (1999) 27 (1): A54.
https://doi.org/10.1042/bst027a054b
Published: 01 February 1999
View article titled, Detergent Solubility and Proteolytic Processing of the Prion Protein
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Articles

Angiotensin converting enzyme and the amyloid precursor protein secretases

Nigel M. Hooper, S. Parvathy, Eric H. Karran, Anthony J. Turner
Journal: Biochemical Society Transactions
Biochem Soc Trans (1999) 27 (1): A23.
https://doi.org/10.1042/bst027a023b
Published: 01 February 1999
View article titled, Angiotensin converting enzyme and the amyloid precursor protein secretases
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Articles

Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins

EDWARD T. PARKIN, ANTHONY J. TURNER, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1998) 26 (3): S241.
https://doi.org/10.1042/bst026s241
Published: 01 August 1998
View article titled, Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins
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Articles

The amyloid precursor protein (APP) and the angiotensin converting enzyme (ACE) secretase are inhibited by hydroxamic acid-based inhibitors

S. Parvathy, Ishrut Hussain, Eric H. Karran, Anthony J. Turner, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (1998) 26 (3): S242.
https://doi.org/10.1042/bst026s242
Published: 01 August 1998
View article titled, The amyloid precursor protein (APP) and the angiotensin converting enzyme (ACE) secretase are inhibited by hydroxamic acid-based inhibitors
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Articles

Molecular characterisation of the alzheimer's amyloid precursor protein secretases

Sarah L. Houldsworth, Alison J. Trew, Nigel M. Hooper, Anthony J. Turner
Journal: Biochemical Society Transactions
Biochem Soc Trans (1998) 26 (3): S245.
https://doi.org/10.1042/bst026s245
Published: 01 August 1998
View article titled, Molecular characterisation of the alzheimer's amyloid precursor protein secretases
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Articles

The cloning and functional expression of human pancreatic aminopeptidase P

Graeme S. Cottrell, Ralph J. Hyde, Nigel M. Hooper, Anthony J. Turner
Journal: Biochemical Society Transactions
Biochem Soc Trans (1998) 26 (3): S248.
https://doi.org/10.1042/bst026s248
Published: 01 August 1998
View article titled, The cloning and functional expression of human pancreatic aminopeptidase P
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Articles

40 Gly-(CSNH)-Phe resists hydrolysis by membrane dipeptidase

JOAN McELROY, DAVID J.S. GUTHRIE, NIGEL M. HOOPER, CARVELL H. WILLIAMS
Journal: Biochemical Society Transactions
Biochem Soc Trans (1998) 26 (1): S31.
https://doi.org/10.1042/bst026s031
Published: 01 February 1998
View article titled, 40 Gly-(CSNH)-Phe resists hydrolysis by membrane dipeptidase
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Articles

A role for calcium and annexins in the formation of caveolae

EDWARD T. PARKIN, ANTHONY J. TURNER, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (3): 444S.
https://doi.org/10.1042/bst024444s
Published: 01 August 1996
View article titled, A role for calcium and annexins in the formation of caveolae
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Articles

Cloning and functional expression of pig kidney aminopeptidase P

RALPH J. HYDE, NIGEL M. HOOPER, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1996) 24 (3): 470S.
https://doi.org/10.1042/bst024470s
Published: 01 August 1996
View article titled, Cloning and functional expression of pig kidney aminopeptidase P
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Articles

Characterisation of porcine aminopeptidase A: a type II integral membrane protein

J. RICHARD HESP, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (4): 550S.
https://doi.org/10.1042/bst023550s
Published: 01 November 1995
View article titled, Characterisation of porcine aminopeptidase A: a type II integral membrane protein
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Articles

Purification and characterization of the angiotensin converting enzyme secretase

CAROLINE CONNOLLY, SYLVESTER Y. OPPONG, ANTHONY J. TURNER, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (4): 551S.
https://doi.org/10.1042/bst023551s
Published: 01 November 1995
View article titled, Purification and characterization of the angiotensin converting enzyme secretase
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Articles

Identification of the site of cleavage in angiotensin converting enzyme by its secretase

NIGEL M. HOOPER, SYLVESTER Y. OPPONG, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (4): 552S.
https://doi.org/10.1042/bst023552s
Published: 01 November 1995
View article titled, Identification of the site of cleavage in angiotensin converting enzyme by its secretase
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Articles

Purification of GPI anchors by immunoaffinity chromatography

SAM P. HEYWOOD, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (1): 101S.
https://doi.org/10.1042/bst023101s
Published: 01 February 1995
View article titled, Purification of GPI anchors by immunoaffinity chromatography
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Articles

Inhibition of two gluconeogenic enzymes by glycosyl-phosphatidylinositol: a model for insulin action

SAM P HEYWOOD, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1994) 22 (1): 10S.
https://doi.org/10.1042/bst022010s
Published: 01 February 1994
View article titled, Inhibition of two gluconeogenic enzymes by glycosyl-phosphatidylinositol: a model for insulin action
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Articles

Inhibitor profile of porcine aminopeptidase W

STEPHEN TIEKU, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (3): 250S.
https://doi.org/10.1042/bst021250s
Published: 01 August 1993
View article titled, Inhibitor profile of porcine aminopeptidase W
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Articles

Characterization of the soluble and membrane-bound forms of porcine angiotensin converting enzyme

SYLVESTER Y. OPPONG, ANTHONY J. TURNER, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (3): 251S.
https://doi.org/10.1042/bst021251s
Published: 01 August 1993
View article titled, Characterization of the soluble and membrane-bound forms of porcine angiotensin converting enzyme
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Articles

Membrane peptidase expression by confluent cultures of Caco-2 cells

IAN A. BREWIS, STEVEN HOWELL, NIGEL M. HOOPER, A. JOHN KENNY, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (3): 252S.
https://doi.org/10.1042/bst021252s
Published: 01 August 1993
View article titled, Membrane peptidase expression by confluent cultures of Caco-2 cells
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Articles

Aminopeptidase P: Immunoaffinity purification and molecular characterisation

GEORGINA S. LLOYD, NICOLETTE T. HABGOOD, NIGEL M. HOOPER, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (3): 236S.
https://doi.org/10.1042/bst021236s
Published: 01 August 1993
View article titled, Aminopeptidase P: Immunoaffinity purification and molecular characterisation
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Articles

Structural determination of the glycolipid anchors of human and porcine membrane dipeptidases

IAN A. BREWIS, MICHAEL A. J. FERGUSON, ANTHONY J. TURNER, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (1): 46S.
https://doi.org/10.1042/bst021046s
Published: 01 February 1993
View article titled, Structural determination of the glycolipid anchors of human and porcine membrane dipeptidases
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Articles

Identification of the site of attachment of the glycolipid anchor in porcine membrane dipeptidase

IAN A. BREWIS, NIGEL M. HOOPER, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (1): 44S.
https://doi.org/10.1042/bst021044s
Published: 01 February 1993
View article titled, Identification of the site of attachment of the glycolipid anchor in porcine membrane dipeptidase
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Articles

Investigation of glycolipid anchor addition using a synthetic peptide as substrate

SAMANTHA J. BROOMFIELD, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (1): 45S.
https://doi.org/10.1042/bst021045s
Published: 01 February 1993
View article titled, Investigation of glycolipid anchor addition using a synthetic peptide as substrate
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Articles

Characterization of the post-translational release from membranes of angiotensin converting enzyme

SYLVESTER Y. OPPONG, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (3): 253S.
https://doi.org/10.1042/bst020253s
Published: 01 August 1992
View article titled, Characterization of the post-translational release from membranes of angiotensin converting enzyme
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Articles

Immunological studies on the endothelial and testicular forms of angiotensin converting enzyme

TRACY A. WILLIAMS, NIGEL M. HOOPER, KAY BARNES, A. JOHN KENNY, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (3): 281S.
https://doi.org/10.1042/bst020281s
Published: 01 August 1992
View article titled, Immunological studies on the endothelial and testicular forms of angiotensin converting enzyme
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Articles

Purification and characterisation of antibodies to the glycosylphosphatidylinositol anchor of human membrane dipeptidase

SAMANTHA J. BROOMFIELD, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (2): 118S.
https://doi.org/10.1042/bst020118s
Published: 01 May 1992
View article titled, Purification and characterisation of antibodies to the glycosylphosphatidylinositol anchor of human membrane dipeptidase
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Articles

Molecular forms of angiotensin-converting enzyme in brain microvessels

TRACY A. WILLIAMS, NIGEL M. HOOPER, A. JOHN KENNY, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1990) 18 (5): 887.
https://doi.org/10.1042/bst0180887
Published: 01 October 1990
View article titled, Molecular forms of angiotensin-converting enzyme in brain microvessels
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Articles

Phosphatidylinositol-glycan-tailed membrane proteins: the biochemistry of glycolipid anchors

ANTHONY J. TURNER, NIGEL M. HOOPER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1989) 17 (5): 864–866.
https://doi.org/10.1042/bst0170864
Published: 01 October 1989
View article titled, Phosphatidylinositol-glycan-tailed membrane proteins: the biochemistry of glycolipid anchors
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Articles

Hydrolysis of the glycosyl-phosphatidylinositol anchors of renal microvillar peptidases by a plasma phospholipase D

NIGEL M. HOOPER, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1989) 17 (5): 885–886.
https://doi.org/10.1042/bst0170885
Published: 01 October 1989
View article titled, Hydrolysis of the glycosyl-phosphatidylinositol anchors of renal microvillar peptidases by a plasma phospholipase D
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Articles

Characterization and isolation of the membrane anchor of angiotensin-converting enzyme

NIGEL M. HOOPER, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1989) 17 (4): 660–661.
https://doi.org/10.1042/bst0170660
Published: 01 August 1989
View article titled, Characterization and isolation of the membrane anchor of angiotensin-converting enzyme
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Articles

Detergent solubilization of phosphatidylinositol-anchored ectoenzymes

NIGEL M. HOOPER, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1988) 16 (4): 583–584.
https://doi.org/10.1042/bst0160583
Published: 01 August 1988
View article titled, Detergent solubilization of phosphatidylinositol-anchored ectoenzymes
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Articles

Characterization of angiotensin-converting enzyme from pig brain

NIGEL M. HOOPER, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (6): 1249–1250.
https://doi.org/10.1042/bst0141249
Published: 01 December 1986
View article titled, Characterization of angiotensin-converting enzyme from pig brain
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Articles

The hydrolysis of neurokinins A and B by cell-surface peptidases

NIGEL M. HOOPER, ANTHONY J. TURNER
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (2): 348–349.
https://doi.org/10.1042/bst0140348
Published: 01 April 1986
View article titled, The hydrolysis of neurokinins A and B by cell-surface peptidases
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