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RICHARD M. DENTON
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Articles

Studies with wortmannin indicate that insulin stimulation of lipogenesis involves multiple signalling pathways

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S. KELLY MOULE, NIGEL J. EDGELL, GAVIN I. WELSH, TRICIA A. DIGGLE, CHRISTOPHER G. PROUD, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (2): 206S.
https://doi.org/10.1042/bst023206s
Published: 01 May 1995
View articletitled, Studies with wortmannin indicate that insulin stimulation of lipogenesis involves multiple signalling pathways
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Articles

Purification of an insulin-stimulated acetyl-CoA carboxylase kinase from rat epididymal adipose tissue

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KATE J. HEESOM, S. KELLY MOULE, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (2): 180S.
https://doi.org/10.1042/bst023180s
Published: 01 May 1995
View articletitled, Purification of an insulin-stimulated acetyl-CoA carboxylase kinase from rat epididymal adipose tissue
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Articles

Characterisation of a novel “22kDa” phosphoprotein which may be important in insulin action

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TRICIA A. DIGGLE, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (2): 209S.
https://doi.org/10.1042/bst023209s
Published: 01 May 1995
View articletitled, Characterisation of a novel “22kDa” phosphoprotein which may be important in insulin action
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Articles

The role of intramitochondrial Ca 2+ in the regulation of oxidative phosphorylation in mammalian tissues

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James G. McCormack, Richard M. Denton
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (3): 793–799.
https://doi.org/10.1042/bst0210793
Published: 01 August 1993
View articletitled, The role of intramitochondrial Ca 2+ in the regulation of oxidative phosphorylation in mammalian tissues
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Articles

Insulin-activated protein kinases in fat and other cells

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Richard M. Denton, Jeremy M. Tavaré, Andrew Borthwick, Martin Dickens, Tricia A. Diggle, Nigel J. Edged, Kate J. Heesom, Tarik Isaad, Deborah F. Lynch, S. Kelly Moule, Carsten Schmitz-Peiffer, Gavin I. Welsh
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (3): 659–664.
https://doi.org/10.1042/bst0200659
Published: 01 August 1992
View articletitled, Insulin-activated protein kinases in fat and other cells
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Articles

Mitochondrial Ca 2+ transport and the role of matrix Ca 2+ in mammalian tissues

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James G. McCormack, Rachael L. Daniel, Nicola J. Osbaldeston, Guy A. Rutter, Richard M. Denton
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (1): 153–159.
https://doi.org/10.1042/bst0200153
Published: 01 February 1992
View articletitled, Mitochondrial Ca 2+ transport and the role of matrix Ca 2+ in mammalian tissues
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Articles

Measurement of matrix Mg 2+ concentration of rat heart mitochondria using fluorescent probes

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GUY A. RUTTER, NICOLA J. OSBALDESTON, JAMES G. McCORMACK, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1990) 18 (5): 894–895.
https://doi.org/10.1042/bst0180894
Published: 01 October 1990
View articletitled, Measurement of matrix Mg 2+ concentration of rat heart mitochondria using fluorescent probes
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Articles

Analysis of the sites of phosphorylation of the insulin receptor in vitro and in vivo

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JEREMY M. TAVARÉ, RICHARD M. OBRIEN, T. S. PILLAY, MARTIN DICKENS, KENNETH SIDDLE, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1988) 16 (6): 1065–1066.
https://doi.org/10.1042/bst0161065
Published: 01 December 1988
View articletitled, Analysis of the sites of phosphorylation of the insulin receptor in vitro and in vivo
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Articles

Rapid purification and properties of pig heart NAD + -isocitrate dehydrogenase

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GUY A. RUTTER, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1988) 16 (5): 873–874.
https://doi.org/10.1042/bst0160873
Published: 01 October 1988
View articletitled, Rapid purification and properties of pig heart NAD + -isocitrate dehydrogenase
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Articles

The regulation of mitochondrial function in mammalian cells by Ca 2 + ions

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JAMES G. McCORMACK, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1988) 16 (4): 523–527.
https://doi.org/10.1042/bst0160523
Published: 01 August 1988
View articletitled, The regulation of mitochondrial function in mammalian cells by Ca 2 + ions
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Articles

Regulation of 2-oxoglutarate dehydrogenase and NAD-linked isocitrate dehydrogenase within toluene-permeabilized mitochondria

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GUY A. RUTTER, PETER J. W. MIDGLEY, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (5): 834–835.
https://doi.org/10.1042/bst0150834
Published: 01 October 1987
View articletitled, Regulation of 2-oxoglutarate dehydrogenase and NAD-linked isocitrate dehydrogenase within toluene-permeabilized mitochondria
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Articles

The control of pyruvate dehydrogenase phosphate phosphatase by Ca 2+ and Mg 2+ ions

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PETER J. W. MIDGLEY, GUY A. RUTTER, ANDREW P. THOMAS, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (5): 835–836.
https://doi.org/10.1042/bst0150835
Published: 01 October 1987
View articletitled, The control of pyruvate dehydrogenase phosphate phosphatase by Ca 2+ and Mg 2+ ions
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Articles

Mechanisms involved in the short-term regulation of acetyl-CoA carboxylase by insulin

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ANDREW C. BORTHWICK, NIGEL J. EDGELL, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (3): 563–565.
https://doi.org/10.1042/bst0140563
Published: 01 June 1986
View articletitled, Mechanisms involved in the short-term regulation of acetyl-CoA carboxylase by insulin
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Articles

Glycogen metabolism in rat interscapular brown adipose tissue

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JANINE M. GIBBINS, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (2): 278.
https://doi.org/10.1042/bst0140278
Published: 01 April 1986
View articletitled, Glycogen metabolism in rat interscapular brown adipose tissue
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Articles

Lipogenesis in brown adipose tissue and its regulation

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JAMES G. McCORMACK, JANINE M. GIBBINS, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (2): 227–230.
https://doi.org/10.1042/bst0140227
Published: 01 April 1986
View articletitled, Lipogenesis in brown adipose tissue and its regulation
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Articles

Insulin-activated acetyl-CoA carboxylase kinase in Triton extracts of human placenta membranes

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JEREMY M. TAVARE, JEAN E. SMYTH, ANDREW C. BORTHWICK, ROGER W. BROWNSEY, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (4): 734–735.
https://doi.org/10.1042/bst0130734
Published: 01 August 1985
View articletitled, Insulin-activated acetyl-CoA carboxylase kinase in Triton extracts of human placenta membranes
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Articles

Hormonal control of intramitochondrial Ca 2+ -sensitive enzymes in heart, liver and adipose tissue

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JAMES G. McCORMACK, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1985) 13 (4): 664–669.
https://doi.org/10.1042/bst0130664
Published: 01 August 1985
View articletitled, Hormonal control of intramitochondrial Ca 2+ -sensitive enzymes in heart, liver and adipose tissue
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Articles

Protein kinases and insulin action in fat cells

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RICHARD M. DENTON, ROGER W. BROWNSEY, TIMOTHY J. HOPKIRK, GRAHAM J. BELSHAM
Journal: Biochemical Society Transactions
Biochem Soc Trans (1984) 12 (5): 768–771.
https://doi.org/10.1042/bst0120768
Published: 01 October 1984
View articletitled, Protein kinases and insulin action in fat cells
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Articles

Evidence to suggest that adrenaline activates rat heart pyruvate dehydrogenase by increasing the concentration of intramitochondrial Ca 2+

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JAMES G. McCORMACK, NIGEL J. EDGELL, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (5): 459–460.
https://doi.org/10.1042/bst0090459
Published: 01 October 1981
View articletitled, Evidence to suggest that adrenaline activates rat heart pyruvate dehydrogenase by increasing the concentration of intramitochondrial Ca 2+
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Articles

Ca 2+ AND THE REGULATION OF INTRAMITOCHONDRIAL METABOLISM IN THE HEART

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James G. McCormack, Richard M. Denton
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (2): 132P.
https://doi.org/10.1042/bst009132pe
Published: 01 April 1981
View articletitled, Ca 2+ AND THE REGULATION OF INTRAMITOCHONDRIAL METABOLISM IN THE HEART
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Articles

EVIDENCE THAT THE ACTIVATION OF ACETYL COA CARBOXYLASE BY INSULIN IN WHITE ADIPOSE TISSUE INVOLVES CAMP-INDEPENDENT PHOSPHORYLATION

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Roger W. Brownsey, Graham J. Belsham, Richard M. Denton
Journal: Biochemical Society Transactions
Biochem Soc Trans (1981) 9 (2): 232P.
https://doi.org/10.1042/bst009232pb
Published: 01 April 1981
View articletitled, EVIDENCE THAT THE ACTIVATION OF ACETYL COA CARBOXYLASE BY INSULIN IN WHITE ADIPOSE TISSUE INVOLVES CAMP-INDEPENDENT PHOSPHORYLATION
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Articles

The activation of isocitrate dehydrogenase (NAD + ) by Ca 2+ within intact uncoupled rat brown adipose tissue mitochondria incubated in the presence and absence of albumin

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JAMES G. McCORMACK, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1980) 8 (3): 339.
https://doi.org/10.1042/bst0080339
Published: 01 June 1980
View articletitled, The activation of isocitrate dehydrogenase (NAD + ) by Ca 2+ within intact uncoupled rat brown adipose tissue mitochondria incubated in the presence and absence of albumin
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Articles

The role of calcium in the regulation of mitochondrial metabolism

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RICHARD M. DENTON, JAMES G. McCORMACK
Journal: Biochemical Society Transactions
Biochem Soc Trans (1980) 8 (3): 266–268.
https://doi.org/10.1042/bst0080266
Published: 01 June 1980
View articletitled, The role of calcium in the regulation of mitochondrial metabolism
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Articles

Evidence for Multi-Site Phosphorylation of Pyruvate Dehydrogenase within Intact Mitochondria

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WILLIAM A. HUGHES, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1978) 6 (6): 1228–1230.
https://doi.org/10.1042/bst0061228
Published: 01 December 1978
View articletitled, Evidence for Multi-Site Phosphorylation of Pyruvate Dehydrogenase within Intact Mitochondria
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Articles

Regulation of Fatty Acid Synthesis and Esterification in Rat Epididymal Adipose Tissue: Effects of Insulin, Palmitate and 2-Bromopalmitate

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GWENAN L. EVANS, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (5): 1288–1291.
https://doi.org/10.1042/bst0051288
Published: 01 October 1977
View articletitled, Regulation of Fatty Acid Synthesis and Esterification in Rat Epididymal Adipose Tissue: Effects of Insulin, Palmitate and 2-Bromopalmitate
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Articles

Effects of Fluoroacetate and (—)-Hydroxycitrate on Fatty Acid Synthesis in Rat Epididymal Adipose Tissue

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ROGER W. BROWNSEY, BARBARA J. BRIDGES, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1977) 5 (5): 1286–1288.
https://doi.org/10.1042/bst0051286
Published: 01 October 1977
View articletitled, Effects of Fluoroacetate and (—)-Hydroxycitrate on Fatty Acid Synthesis in Rat Epididymal Adipose Tissue
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Articles

Alterations in Adipose-Tissue Pyruvate Dehydrogenase Activity in Starved, Fat-Fed and Diabetic Rats

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DAVID STANSBIE, RICHARD M. DENTON, PHILIP J. RANDLE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1975) 3 (5): 718–720.
https://doi.org/10.1042/bst0030718
Published: 01 October 1975
View articletitled, Alterations in Adipose-Tissue Pyruvate Dehydrogenase Activity in Starved, Fat-Fed and Diabetic Rats
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Articles

Acute Hormonal Regulation of Fatty Acid Synthesis in Rat Epididymal Fat-Pads

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RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1974) 2 (6): 1208–1213.
https://doi.org/10.1042/bst0021208
Published: 01 December 1974
View articletitled, Acute Hormonal Regulation of Fatty Acid Synthesis in Rat Epididymal Fat-Pads
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Articles

Inhibition of Mitochondria1 Pyruvate Transport by Phenylpyruvate and α-Oxo-4-methylpentanoate

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ANDREW P. HALESTRAP, MARTIN D. BRAND, RICHARD M. DENTON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1974) 2 (5): 980–982.
https://doi.org/10.1042/bst0020980
Published: 01 October 1974
View articletitled, Inhibition of Mitochondria1 Pyruvate Transport by Phenylpyruvate and α-Oxo-4-methylpentanoate
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