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Simon J. Cook
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Articles

Inhibition of RAF dimers: it takes two to tango

Open Access
Frazer A. Cook, Simon J. Cook
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 237–251.
https://doi.org/10.1042/BST20200485
Published: 24 December 2020
View articletitled, Inhibition of RAF dimers: it takes two to tango
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Articles

Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for…

Open Access
Simon J. Cook, Julie A. Tucker, Pamela A. Lochhead
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 1859–1875.
https://doi.org/10.1042/BST20190338
Published: 11 September 2020
View articletitled, Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for…
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Articles

Intrinsic and acquired resistance to MEK1/2 inhibitors in cancer

Available to Purchase
Matthew J. Sale, Simon J. Cook
Journal: Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (4): 776–783.
https://doi.org/10.1042/BST20140129
Published: 11 August 2014
View articletitled, Intrinsic and acquired resistance to MEK1/2 inhibitors in cancer
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Articles

Adaptation to chronic mTOR inhibition in cancer and in aging

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Rebecca Gilley, Kathryn Balmanno, Claire L. Cope, Simon J. Cook
Journal: Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (4): 956–961.
https://doi.org/10.1042/BST20130080
Published: 18 July 2013
View articletitled, Adaptation to chronic mTOR inhibition in cancer and in aging
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Articles

Regulation of MEK/ERK pathway output by subcellular localization of B-Raf

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Catherine Andreadi, Catherine Noble, Bipin Patel, Hong Jin, Maria M. Aguilar Hernandez, Kathryn Balmanno, Simon J. Cook, Catrin Pritchard
Journal: Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 67–72.
https://doi.org/10.1042/BST20110621
Published: 19 January 2012
View articletitled, Regulation of MEK/ERK pathway output by subcellular localization of B-Raf
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Articles

Tumour cell responses to MEK1/2 inhibitors: acquired resistance and pathway remodelling

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Annette S. Little, Kathryn Balmanno, Matthew J. Sale, Paul D. Smith, Simon J. Cook
Journal: Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 73–78.
https://doi.org/10.1042/BST20110647
Published: 19 January 2012
View articletitled, Tumour cell responses to MEK1/2 inhibitors: acquired resistance and pathway remodelling
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Articles

ERK5 and its role in tumour development

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Pamela A. Lochhead, Rebecca Gilley, Simon J. Cook
Journal: Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 251–256.
https://doi.org/10.1042/BST20110663
Published: 19 January 2012
View articletitled, ERK5 and its role in tumour development
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Articles

Regulation of Cell Cycle Re-entry by Growth, Survival & Stress Signalling Pathways

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Simon J. Cook, Kathryn Balmanno, Andrew Garner, Tracy Millar, Claire Taverner, Daniel Todd
Journal: Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (1): A3.
https://doi.org/10.1042/bst028a003a
Published: 01 February 2000
View articletitled, Regulation of Cell Cycle Re-entry by Growth, Survival & Stress Signalling Pathways
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Articles

Epidermal growth factor stimulates phospholipase D activity in the absence of inositol lipid hydrolysis in Swiss 3T3 cells

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Simon J. Cook, Michael J. O. Wakelam
Journal: Biochemical Society Transactions
Biochem Soc Trans (1991) 19 (2): 108S.
https://doi.org/10.1042/bst019108s
Published: 01 April 1991
View articletitled, Epidermal growth factor stimulates phospholipase D activity in the absence of inositol lipid hydrolysis in Swiss 3T3 cells
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Articles

Regulation of the hydrolysis of phosphatidylcholine in Swiss 3T3 cells

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Michael J. O. Wakelam, Simon J. Cook, Susan Currie, Susan Palmer, Robin Plevin
Journal: Biochemical Society Transactions
Biochem Soc Trans (1991) 19 (2): 321–324.
https://doi.org/10.1042/bst0190321
Published: 01 April 1991
View articletitled, Regulation of the hydrolysis of phosphatidylcholine in Swiss 3T3 cells
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Articles

Bombesin and platelet-derived growth factor stimulate phosphatidylcholine breakdown by a common mechanism

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SIMON J. COOK, ROBIN PLEVIN, SUSAN PALMER, MICHAEL J. O. WAKELAM
Journal: Biochemical Society Transactions
Biochem Soc Trans (1990) 18 (3): 484–485.
https://doi.org/10.1042/bst0180484
Published: 01 June 1990
View articletitled, Bombesin and platelet-derived growth factor stimulate phosphatidylcholine breakdown by a common mechanism
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