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Articles

Advances in ribosome profiling technologies

Open Access
Kotaro Tomuro, Shintaro Iwasaki
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (03): 555–564.
https://doi.org/10.1042/BST20253061
Published: 16 May 2025
View articletitled, Advances in ribosome profiling technologies
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Articles

Emerging tools and methods to study cell signalling mediated by branched ubiquitin chains

Open Access
Matthew R. McFarland, Yogesh Kulathu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (03): 579–592.
https://doi.org/10.1042/BST20253015
Published: 16 May 2025
View articletitled, Emerging tools and methods to study cell signalling mediated by branched ubiquitin chains
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Articles

Progress toward a comprehensive brain protein interactome

Available to Purchase
Vy Dang, Brittney Voigt, Edward M. Marcotte
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 303–314.
https://doi.org/10.1042/BST20241135
Published: 12 February 2025
View articletitled, Progress toward a comprehensive brain protein interactome
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Articles

Advances in nanobody multimerization and multispecificity: from in vivo assembly to in vitro production

Open Access
Mohammed Al-Seragi, Yilun Chen, Franck Duong van Hoa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 235–248.
https://doi.org/10.1042/BST20241419
Published: 07 February 2025
View articletitled, Advances in nanobody multimerization and multispecificity: from in vivo assembly to in vitro production
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Articles

Beyond the mono-nucleosome

Open Access
Juliana Kikumoto Dias, Sheena D’Arcy
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 69–81.
https://doi.org/10.1042/BST20230721
Published: 31 January 2025
View articletitled, Beyond the mono-nucleosome
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Articles

Quaternary arrangements of membrane proteins: an aquaporin case

Open Access
Maria Hrmova
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2557–2568.
https://doi.org/10.1042/BST20241630
Published: 13 December 2024
View articletitled, Quaternary arrangements of membrane proteins: an aquaporin case
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Articles

Tools and techniques for quantitative glycoproteomic analysis

Available to Purchase
Siyuan Kong, Wei Zhang, Weiqian Cao
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2439–2453.
https://doi.org/10.1042/BST20240257
Published: 10 December 2024
View articletitled, Tools and techniques for quantitative glycoproteomic analysis
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Articles

Cryo-electron tomography: en route to the molecular anatomy of organisms and tissues

Open Access
Oda Helene Schiøtz, Sven Klumpe, Juergen M. Plitzko, Christoph J. O. Kaiser
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2415–2425.
https://doi.org/10.1042/BST20240173
Published: 06 December 2024
View articletitled, Cryo-electron tomography: en route to the molecular anatomy of organisms and tissues
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Articles

Exploring the dynamics of messenger ribonucleoprotein-mediated translation repression

Open Access
Julia Meyer, Marco Payr, Olivier Duss, Janosch Hennig
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2267–2279.
https://doi.org/10.1042/BST20231240
Published: 27 November 2024
View articletitled, Exploring the dynamics of messenger ribonucleoprotein-mediated translation repression
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Articles

Advances in utilizing reverse micelles to investigate membrane proteins

Available to Purchase
Sara H. Walters, Aaron S. Birchfield, Brian Fuglestad
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2499–2511.
https://doi.org/10.1042/BST20240830
Published: 07 November 2024
View articletitled, Advances in utilizing reverse micelles to investigate membrane proteins
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Articles

Phase separation and viral factories: unveiling the physical processes supporting RNA packaging in dsRNA viruses

Open Access
Cyril J. Haller, Julia Acker, A. Emilia Arguello, Alexander Borodavka
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2101–2112.
https://doi.org/10.1042/BST20231304
Published: 26 September 2024
View articletitled, Phase separation and viral factories: unveiling the physical processes supporting RNA packaging in dsRNA viruses
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Articles

Enzymes of sphingolipid metabolism as transducers of metabolic inputs

Available to Purchase
Fabiola N. Velazquez, Chiara Luberto, Daniel Canals, Yusuf A. Hannun
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1795–1808.
https://doi.org/10.1042/BST20231442
Published: 05 August 2024
View articletitled, Enzymes of sphingolipid metabolism as transducers of metabolic inputs
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Articles

Exploring the conformational landscapes of protein kinases: perspectives from FRET and DEER

Open Access
Zachary D. Baker, Damien M. Rasmussen, Nicholas M. Levinson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1071–1083.
https://doi.org/10.1042/BST20230558
Published: 23 May 2024
View articletitled, Exploring the conformational landscapes of protein kinases: perspectives from FRET and DEER
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Articles

Reconstituting membrane fission using a high content and throughput assay

Available to Purchase
Uma Swaminathan, Thomas J. Pucadyil
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1449–1457.
https://doi.org/10.1042/BST20231325
Published: 15 May 2024
View articletitled, Reconstituting membrane fission using a high content and throughput assay
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Articles

From bottom-up to cell surface proteomics: detergents or no detergents, that is the question

Open Access
Zora Brough, Zhiyu Zhao, Franck Duong van Hoa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1253–1263.
https://doi.org/10.1042/BST20231020
Published: 26 April 2024
View articletitled, From bottom-up to cell surface proteomics: detergents or no detergents, that is the question
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Articles

RNA m 6 A modification, signals for degradation or stabilisation?

Open Access
Guifeng Wei
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 707–717.
https://doi.org/10.1042/BST20230574
Published: 17 April 2024
View articletitled, RNA m 6 A modification, signals for degradation or stabilisation?
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Articles

New insights into the structure and dynamics of the TOM complex in mitochondria

Open Access
Stephan Nussberger, Robin Ghosh, Shuo Wang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 911–922.
https://doi.org/10.1042/BST20231236
Published: 17 April 2024
View articletitled, New insights into the structure and dynamics of the TOM complex in mitochondria
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Includes: Supplementary data
Articles

Covalent activity-based probes for imaging of serine proteases

Available to Purchase
Marcin Skorenski, Shanping Ji, Steven H. L. Verhelst
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 923–935.
https://doi.org/10.1042/BST20231450
Published: 17 April 2024
View articletitled, Covalent activity-based probes for imaging of serine proteases
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Articles

Decoding the ubiquitin landscape by cutting-edge ubiquitinomic approaches

Available to Purchase
Brindhavanam P T, Indrajit Sahu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 627–637.
https://doi.org/10.1042/BST20230457
Published: 04 April 2024
View articletitled, Decoding the ubiquitin landscape by cutting-edge ubiquitinomic approaches
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Articles

A dynamic role for transcription factors in restoring transcription through mitosis

Open Access
Marek A. Budzyński, Alexander K.L. Wong, Armin Faghihi, Sheila S. Teves
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 821–830.
https://doi.org/10.1042/BST20231022
Published: 25 March 2024
View articletitled, A dynamic role for transcription factors in restoring transcription through mitosis
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Articles

Genome organization across scales: mechanistic insights from in vitro reconstitution studies

Open Access
In Collection
Epigenetics
Elisa Oberbeckmann, A. Marieke Oudelaar
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 793–802.
https://doi.org/10.1042/BST20230883
Published: 07 March 2024
View articletitled, Genome organization across scales: mechanistic insights from in vitro reconstitution studies
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Articles

Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein

Open Access
Mohammed M. Alhadidy, Nicholas M. Kanaan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 301–318.
https://doi.org/10.1042/BST20230596
Published: 13 February 2024
View articletitled, Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein
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Articles

All who wander are not lost: the search for homology during homologous recombination

Open Access
Jingyi Hu, J. Brooks Crickard
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 367–377.
https://doi.org/10.1042/BST20230705
Published: 07 February 2024
View articletitled, All who wander are not lost: the search for homology during homologous recombination
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Articles

Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection

Open Access
In Collection
Coronavirus
Debjit Khan, Paul L. Fox
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (6): 2127–2141.
https://doi.org/10.1042/BST20230527
Published: 18 December 2023
View articletitled, Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection
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Articles

Advances in understanding telomerase assembly

Open Access
Basma M. Klump, Jens C. Schmidt
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (6): 2093–2101.
https://doi.org/10.1042/BST20230269
Published: 18 December 2023
View articletitled, Advances in understanding telomerase assembly
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Articles

New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures

Open Access
Matthieu P.M.H. Benoit, Byron Hunter, John S. Allingham, Hernando Sosa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1505–1520.
https://doi.org/10.1042/BST20221238
Published: 10 August 2023
View articletitled, New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures
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Includes: Supplementary data
Articles

Maximizing the performance of protein-based fluorescent biosensors

Open Access
Fu Chai, Dazhou Cheng, Yusuke Nasu, Takuya Terai, Robert E. Campbell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1585–1595.
https://doi.org/10.1042/BST20221413
Published: 11 July 2023
View articletitled, Maximizing the performance of protein-based fluorescent biosensors
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Articles

How far can omics go in unveiling the mechanisms of floral senescence?

Open Access
Hilary J. Rogers
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1485–1493.
https://doi.org/10.1042/BST20221097
Published: 30 June 2023
View articletitled, How far can omics go in unveiling the mechanisms of floral senescence?
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Articles

Recent advances in membrane mimetics for membrane protein research

Open Access
John William Young
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1405–1416.
https://doi.org/10.1042/BST20230164
Published: 22 June 2023
View articletitled, Recent advances in membrane mimetics for membrane protein research
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Articles

Fast-forward on P-type ATPases: recent advances on structure and function

Available to Purchase
Charlott Stock, Tomáš Heger, Sara Basse Hansen, Sigrid Thirup Larsen, Michael Habeck, Thibaud Dieudonné, Ronja Driller, Poul Nissen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1347–1360.
https://doi.org/10.1042/BST20221543
Published: 02 June 2023
View articletitled, Fast-forward on P-type ATPases: recent advances on structure and function
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Articles

Improving the hole picture: towards a consensus on the mechanism of nuclear transport

Open Access
David Cowburn, Michael Rout
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 871–886.
https://doi.org/10.1042/BST20220494
Published: 26 April 2023
View articletitled, Improving the hole picture: towards a consensus on the mechanism of nuclear transport
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Articles

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Open Access
Zhengyuan Huang, Pei F. Lai, Alexander T. H. Cocker, Stuart M. Haslam, Anne Dell, Hugh J. M. Brady, Mark R. Johnson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 639–653.
https://doi.org/10.1042/BST20221406
Published: 16 March 2023
View articletitled, Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology
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Articles

Single-molecule tracking (SMT): a window into live-cell transcription biochemistry

Open Access
Liza Dahal, Nike Walther, Robert Tjian, Xavier Darzacq, Thomas G.W. Graham
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 557–569.
https://doi.org/10.1042/BST20221242
Published: 06 March 2023
View articletitled, Single-molecule tracking (SMT): a window into live-cell transcription biochemistry
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Articles

Towards using 3D cellular cultures to model the activation and diverse functions of macrophages

Open Access
Sean Cutter, Mark D. Wright, Nicholas P. Reynolds, Katrina Jean Binger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 387–401.
https://doi.org/10.1042/BST20221008
Published: 06 February 2023
View articletitled, Towards using 3D cellular cultures to model the activation and diverse functions of macrophages
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Articles

Eliminating oncogenic RAS: back to the future at the drawing board

Open Access
Candy Laura Steffen, Pelin Kaya, Elisabeth Schaffner-Reckinger, Daniel Abankwa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 447–456.
https://doi.org/10.1042/BST20221343
Published: 23 January 2023
View articletitled, Eliminating oncogenic RAS: back to the future at the drawing board
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Includes: Supplementary data
Articles

Interactions governing transcriptional activity of nuclear receptors

Available to Purchase
Sabab Hasan Khan, C. Denise Okafor
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1941–1952.
https://doi.org/10.1042/BST20220338
Published: 16 December 2022
View articletitled, Interactions governing transcriptional activity of nuclear receptors
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Articles

General strategies for using amino acid sequence data to guide biochemical investigation of protein function

Available to Purchase
Emily N. Kennedy, Clay A. Foster, Sarah A. Barr, Robert B. Bourret
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1847–1858.
https://doi.org/10.1042/BST20220849
Published: 23 November 2022
View articletitled, General strategies for using amino acid sequence data to guide biochemical investigation of protein function
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Articles

Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation

Open Access
Benjamin Rowlinson, Elodie Crublet, Rime Kerfah, Michael J. Plevin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1555–1567.
https://doi.org/10.1042/BST20210586
Published: 16 November 2022
View articletitled, Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation
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Articles

Frankenstein Cas9: engineering improved gene editing systems

Available to Purchase
Pascal D. Vos, Aleksandra Filipovska, Oliver Rackham
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1505–1516.
https://doi.org/10.1042/BST20220873
Published: 28 October 2022
View articletitled, Frankenstein Cas9: engineering improved gene editing systems
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Articles

Characterising ion channel structure and dynamics using fluorescence spectroscopy techniques

Available to Purchase
Shreyas Bhat, Rikard Blunck
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1427–1445.
https://doi.org/10.1042/BST20220605
Published: 25 October 2022
View articletitled, Characterising ion channel structure and dynamics using fluorescence spectroscopy techniques
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Articles

A comprehensive review of methods to study lncRNA–protein interactions in solution

Available to Purchase
Maulik D. Badmalia, Higor Sette Pereira, M. Quadir Siddiqui, Trushar R. Patel
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1415–1426.
https://doi.org/10.1042/BST20220604
Published: 17 October 2022
View articletitled, A comprehensive review of methods to study lncRNA–protein interactions in solution
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Articles

Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques

Open Access
Chung Yu Chan, Youssef Faragalla, Ling-Gang Wu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1157–1167.
https://doi.org/10.1042/BST20210263
Published: 12 August 2022
View articletitled, Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques
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Articles

AAA+ proteins: one motor, multiple ways to work

Available to Purchase
JiaBei Lin, James Shorter, Aaron L. Lucius
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 895–906.
https://doi.org/10.1042/BST20200350
Published: 31 March 2022
View articletitled, AAA+ proteins: one motor, multiple ways to work
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Articles

Stop CRYing! Inhibition of cryptochrome function by small proteins

Open Access
Valdeko Kruusvee, Arendse Maria Toft, Blanche Aguida, Margaret Ahmad, Stephan Wenkel
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 773–782.
https://doi.org/10.1042/BST20190062
Published: 21 March 2022
View articletitled, Stop CRYing! Inhibition of cryptochrome function by small proteins
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Articles

A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences

Open Access
Chidinma Adanna Okolo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 649–663.
https://doi.org/10.1042/BST20210886
Published: 08 March 2022
View articletitled, A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences
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Articles

New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

Open Access
In Collection
Awards
Valerie B. O'Donnell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 1–11.
https://doi.org/10.1042/BST20210579
Published: 28 February 2022
View articletitled, New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease
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Articles

How lipids affect the energetics of co-translational alpha helical membrane protein folding

Open Access
Ryan Brady, Nicola J. Harris, Grant A. Pellowe, Samuel Gulaidi Breen, Paula J. Booth
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 555–567.
https://doi.org/10.1042/BST20201063
Published: 25 February 2022
View articletitled, How lipids affect the energetics of co-translational alpha helical membrane protein folding
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Articles

Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Available to Purchase
Luke T. Marr, Prasoon Jaya, Laxmi N. Mishra, Jeffrey J. Hayes
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 199–212.
https://doi.org/10.1042/BST20210959
Published: 15 February 2022
View articletitled, Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin
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Articles

Multiple roles of Pol epsilon in eukaryotic chromosome replication

Open Access
Milos A. Cvetkovic, Esther Ortega, Roberto Bellelli, Alessandro Costa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 309–320.
https://doi.org/10.1042/BST20210082
Published: 07 February 2022
View articletitled, Multiple roles of Pol epsilon in eukaryotic chromosome replication
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Articles

Artificial protein assemblies with well-defined supramolecular protein nanostructures

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Suyeong Han, Yongwon Jung
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2821–2830.
https://doi.org/10.1042/BST20210808
Published: 23 November 2021
View articletitled, Artificial protein assemblies with well-defined supramolecular protein nanostructures
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