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Articles

Cdk activation by phosphorylation: linking growth signals to cell cycle control

Open Access
Heidi M. Blank, Eun-Gyu No, Michael Polymenis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (03): 521–527.
https://doi.org/10.1042/BST20253004
Published: 09 May 2025
View article titled, Cdk activation by phosphorylation: linking growth signals to cell cycle control
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Articles

How similar are the molecular mechanisms of yeast and metazoan genome replication initiation?

Open Access
Giacomo Palm, Alessandro Costa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (02): 353–361.
https://doi.org/10.1042/BST20220917
Published: 07 March 2025
View article titled, How similar are the molecular mechanisms of yeast and metazoan genome replication initiation?
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Articles

The cellular basis of meristem development in fern gametophytes

Open Access
Chong Xie, Cankui Zhang, Xing Liu, Yun Zhou
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 327–336.
https://doi.org/10.1042/BST20240728
Published: 13 February 2025
View article titled, The cellular basis of meristem development in fern gametophytes
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Articles

Same same but different? How blood and lymphatic vessels induce cell contact inhibition

Open Access
Claudia Carlantoni, Leon M.H. Liekfeld, Manu Beerens, Maike Frye
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 181–191.
https://doi.org/10.1042/BST20240573
Published: 06 February 2025
View article titled, Same same but different? How blood and lymphatic vessels induce cell contact inhibition
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Articles

Exploring the oncogenic roles of T-box transcription factor TBX2 and its potential as a therapeutic target

Open Access
Claire Bellis, Mihlali V. Mlaza, Abid Ali, Amaal Abrahams, Sharon Prince
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 193–204.
https://doi.org/10.1042/BST20241069
Published: 06 February 2025
View article titled, Exploring the oncogenic roles of T-box transcription factor TBX2 and its potential as a therapeutic target
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Articles

Axonemal microtubule dynamics in the assembly and disassembly of cilia

Open Access
Yi Zhang, Mu He, Junmin Pan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 101–111.
https://doi.org/10.1042/BST20240688
Published: 31 January 2025
View article titled, Axonemal microtubule dynamics in the assembly and disassembly of cilia
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Articles

The expanding roles of myonuclei in adult skeletal muscle health and function

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Agnieszka K. Borowik, Kevin A. Murach, Benjamin F. Miller
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2603–2616.
https://doi.org/10.1042/BST20241637
Published: 19 December 2024
View article titled, The expanding roles of myonuclei in adult skeletal muscle health and function
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Articles

Unusual modes of cell and nuclear divisions characterise Drosophila development

Open Access
Qiaolin Yang, Fernando Wijaya, Ridam Kapoor, Harshaa Chandrasekaran, Siddhant Jagtiani, Izaac Moran, Gary R. Hime
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2281–2295.
https://doi.org/10.1042/BST20231341
Published: 07 November 2024
View article titled, Unusual modes of cell and nuclear divisions characterise Drosophila development
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Articles

Untangling bacterial DNA topoisomerases functions

Available to Purchase
Céline Borde, Lisa Bruno, Olivier Espéli
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2321–2331.
https://doi.org/10.1042/BST20240089
Published: 07 November 2024
View article titled, Untangling bacterial DNA topoisomerases functions
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Articles

Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction

Open Access
Sneha S. Varghese, Alessandro Giovanni Hernandez-De La Peña, Sangeeta Dhawan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2133–2144.
https://doi.org/10.1042/BST20231519
Published: 04 October 2024
View article titled, Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction
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Articles

A second generation of senotherapies: the development of targeted senolytics, senoblockers and senoreversers for healthy ageing

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Vinesh Dhokia, Amal Albati, Hannah Smith, Gethin Thomas, Salvador Macip
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1661–1671.
https://doi.org/10.1042/BST20231066
Published: 28 June 2024
View article titled, A second generation of senotherapies: the development of targeted senolytics, senoblockers and senoreversers for healthy ageing
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Articles

Research progress of ZIC5 for tumor metastasis

Available to Purchase
Yiming Zhong, Shangzhi Yang, Xianli Wang, Chuanyu Sun
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1363–1372.
https://doi.org/10.1042/BST20231263
Published: 15 May 2024
View article titled, Research progress of ZIC5 for tumor metastasis
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Articles

Deubiquitinases in muscle physiology and disorders

Open Access
Cyriel S. Olie, Darragh P. O'Brien, Hannah B.L. Jones, Zhu Liang, Andreas Damianou, Ilknur Sur-Erdem, Adán Pinto-Fernández, Vered Raz, Benedikt M. Kessler
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1085–1098.
https://doi.org/10.1042/BST20230562
Published: 08 May 2024
View article titled, Deubiquitinases in muscle physiology and disorders
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Articles

The molecular mechanisms driving Plasmodium cell division

Open Access
David S. Guttery, Mohammad Zeeshan, Anthony A. Holder, Rita Tewari
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 593–602.
https://doi.org/10.1042/BST20230403
Published: 02 April 2024
View article titled, The molecular mechanisms driving Plasmodium cell division
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Articles

The role of lipids in genome integrity and pluripotency

Open Access
Qiyu Tian, Hoyoung Chung, Duancheng Wen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 639–650.
https://doi.org/10.1042/BST20230479
Published: 20 March 2024
View article titled, The role of lipids in genome integrity and pluripotency
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Articles

Transcriptional control of neural stem cell activity

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Takashi Kaise, Ryoichiro Kageyama
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 617–626.
https://doi.org/10.1042/BST20230439
Published: 13 March 2024
View article titled, Transcriptional control of neural stem cell activity
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Articles

Friend or foe? Reciprocal regulation between E3 ubiquitin ligases and deubiquitinases

Available to Purchase
Derek L. Bolhuis, Michael J. Emanuele, Nicholas G. Brown
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 241–267.
https://doi.org/10.1042/BST20230454
Published: 28 February 2024
View article titled, Friend or foe? Reciprocal regulation between E3 ubiquitin ligases and deubiquitinases
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Articles

Transcriptional repression across mitosis: mechanisms and functions

Open Access
A. Contreras, C. Perea-Resa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 455–464.
https://doi.org/10.1042/BST20231071
Published: 19 February 2024
View article titled, Transcriptional repression across mitosis: mechanisms and functions
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Articles

The molecular machinery of meiotic recombination

Open Access
Linda Chen, John R. Weir
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 379–393.
https://doi.org/10.1042/BST20230712
Published: 13 February 2024
View article titled, The molecular machinery of meiotic recombination
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Articles

Kinetochore–microtubule error correction for biorientation: lessons from yeast

Open Access
Shuyu Li, Taciana Kasciukovic, Tomoyuki U. Tanaka
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 29–39.
https://doi.org/10.1042/BST20221261
Published: 02 February 2024
View article titled, Kinetochore–microtubule error correction for biorientation: lessons from yeast
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Articles

The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer

Open Access
Samuel J. Rodgers, Christina A. Mitchell, Lisa M. Ooms
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1459–1472.
https://doi.org/10.1042/BST20220866
Published: 20 July 2023
View article titled, The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer
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Articles

Contributions of coxsackievirus adenovirus receptor to tumorigenesis

Open Access
Claudia Owczarek, Yassmin Elmasry, Maddy Parsons
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1143–1155.
https://doi.org/10.1042/BST20221203
Published: 12 June 2023
View article titled, Contributions of coxsackievirus adenovirus receptor to tumorigenesis
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Articles

Mechanisms of epithelial growth and development in the zebrafish intestine

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Reegan J. Willms, Edan Foley
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1213–1224.
https://doi.org/10.1042/BST20221375
Published: 09 June 2023
View article titled, Mechanisms of epithelial growth and development in the zebrafish intestine
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Articles

The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis

Open Access
Fabian Gude, Jurij Froese, Georg Steffes, Kay Grobe
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 983–993.
https://doi.org/10.1042/BST20220719
Published: 24 May 2023
View article titled, The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis
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Articles

The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism

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Qiang Zhang, Bin Tian
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1111–1119.
https://doi.org/10.1042/BST20221128
Published: 12 May 2023
View article titled, The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism
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Articles

The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication

Open Access
Yuki Hatoyama, Masato T. Kanemaki
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1289–1295.
https://doi.org/10.1042/BST20221465
Published: 05 May 2023
View article titled, The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication
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Articles

The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation

Open Access
Shang Liang, Rajaei Almohammed, Victoria H. Cowling
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1131–1141.
https://doi.org/10.1042/BST20221154
Published: 05 May 2023
View article titled, The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation
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Includes: Supplementary data
Articles

The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?

Open Access
Chloe Girard, David Zwicker, Raphael Mercier
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1179–1190.
https://doi.org/10.1042/BST20221329
Published: 05 May 2023
View article titled, The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?
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Includes: Multimedia, Supplementary data
Articles

The molecular mechanisms of human separase regulation

Open Access
Jun Yu, David O. Morgan, Andreas Boland
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1225–1233.
https://doi.org/10.1042/BST20221400
Published: 04 May 2023
View article titled, The molecular mechanisms of human separase regulation
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Articles

Regulation of mTORC1 by the Rag GTPases

Open Access
Tshering D. Lama-Sherpa, Mi-Hyeon Jeong, Jenna L. Jewell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 655–664.
https://doi.org/10.1042/BST20210038
Published: 16 March 2023
View article titled, Regulation of mTORC1 by the Rag GTPases
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Articles

Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling

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Tahir Muhammad, Jian Li
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 501–512.
https://doi.org/10.1042/BST20220616
Published: 09 March 2023
View article titled, Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling
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Articles

Targeting NRF2 to promote epithelial repair

Open Access
Paul Hiebert, Sabine Werner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 101–111.
https://doi.org/10.1042/BST20220228
Published: 10 February 2023
View article titled, Targeting NRF2 to promote epithelial repair
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Articles

Mechanisms of germ cell survival and plasticity in Caenorhabditis elegans

Open Access
Wei Cao, Roger Pocock
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1517–1526.
https://doi.org/10.1042/BST20220878
Published: 05 October 2022
View article titled, Mechanisms of germ cell survival and plasticity in Caenorhabditis elegans
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Articles

Processing DNA lesions during mitosis to prevent genomic instability

Open Access
Anastasia Audrey, Lauren de Haan, Marcel A.T.M. van Vugt, H. Rudolf de Boer
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1105–1118.
https://doi.org/10.1042/BST20220049
Published: 30 August 2022
View article titled, Processing DNA lesions during mitosis to prevent genomic instability
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Articles

Tumour invasion and dissemination

Open Access
Ryan Lusby, Philip Dunne, Vijay K. Tiwari
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1245–1257.
https://doi.org/10.1042/BST20220452
Published: 17 June 2022
View article titled, Tumour invasion and dissemination
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Articles

CDK activity sensors: genetically encoded ratiometric biosensors for live analysis of the cell cycle

Available to Purchase
Michael A. Q. Martinez, David Q. Matus
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1081–1090.
https://doi.org/10.1042/BST20211131
Published: 08 June 2022
View article titled, CDK activity sensors: genetically encoded ratiometric biosensors for live analysis of the cell cycle
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Articles

Mitotic drive in asymmetric epigenetic inheritance

Open Access
Rajesh Ranjan, Xin Chen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 675–688.
https://doi.org/10.1042/BST20200267
Published: 19 April 2022
View article titled, Mitotic drive in asymmetric epigenetic inheritance
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Articles

Functional diversity in the RAS subfamily of small GTPases

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Gabriela Bernal Astrain, Maya Nikolova, Matthew J. Smith
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 921–933.
https://doi.org/10.1042/BST20211166
Published: 31 March 2022
View article titled, Functional diversity in the RAS subfamily of small GTPases
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Articles

PIDD1 in cell cycle control, sterile inflammation and cell death

Open Access
In Collection
Cell death and survival
Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 813–824.
https://doi.org/10.1042/BST20211186
Published: 28 March 2022
View article titled, PIDD1 in cell cycle control, sterile inflammation and cell death
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Articles

The intricate roles of RCC1 in normal cells and cancer cells

Available to Purchase
Li Jing, Hang Fai Kwok
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 83–93.
https://doi.org/10.1042/BST20210861
Published: 22 February 2022
View article titled, The intricate roles of RCC1 in normal cells and cancer cells
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Articles

Bioimaging approaches for quantification of individual cell behavior during cell fate decisions

Available to Purchase
Karine R. Begnini, Luiza C. Pereira, Juliano L. Faccioni, Guido Lenz, Eduardo C. Filippi-Chiela
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 513–527.
https://doi.org/10.1042/BST20210534
Published: 15 February 2022
View article titled, Bioimaging approaches for quantification of individual cell behavior during cell fate decisions
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Articles

Chromosome clustering in mitosis by the nuclear protein Ki-67

Open Access
Konstantinos Stamatiou, Paola Vagnarelli
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2767–2776.
https://doi.org/10.1042/BST20210717
Published: 16 November 2021
View article titled, Chromosome clustering in mitosis by the nuclear protein Ki-67
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Articles

Identifying key regulators of the intestinal stem cell niche

Open Access
Carrie A. Duckworth
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2163–2176.
https://doi.org/10.1042/BST20210223
Published: 19 October 2021
View article titled, Identifying key regulators of the intestinal stem cell niche
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Articles

Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers

Open Access
In Collection
Cell death and survival
W. Douglas Fairlie, Erinna F. Lee
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2397–2410.
https://doi.org/10.1042/BST20210750
Published: 28 September 2021
View article titled, Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers
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Articles

Efficiency and equity in origin licensing to ensure complete DNA replication

Available to Purchase
Liu Mei, Jeanette Gowen Cook
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2133–2141.
https://doi.org/10.1042/BST20210161
Published: 21 September 2021
View article titled, Efficiency and equity in origin licensing to ensure complete DNA replication
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Articles

Progress and challenges in understanding the regulation and function of p53 dynamics

Open Access
Zhilin Yang, Ryan L. Hanson, Eric Batchelor
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2123–2131.
https://doi.org/10.1042/BST20210148
Published: 08 September 2021
View article titled, Progress and challenges in understanding the regulation and function of p53 dynamics
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Articles

Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases

Open Access
Matthew D. Worssam, Helle F. Jørgensen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2101–2111.
https://doi.org/10.1042/BST20210138
Published: 08 September 2021
View article titled, Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases
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Articles

How neural stem cells contribute to neocortex development

Open Access
Lei Xing, Michaela Wilsch-Bräuninger, Wieland B. Huttner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 1997–2006.
https://doi.org/10.1042/BST20200923
Published: 16 August 2021
View article titled, How neural stem cells contribute to neocortex development
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Articles

Cellular feedback dynamics and multilevel regulation driven by the hippo pathway

Open Access
Jiwon Park, Carsten Gram Hansen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1515–1527.
https://doi.org/10.1042/BST20200253
Published: 10 August 2021
View article titled, Cellular feedback dynamics and multilevel regulation driven by the hippo pathway
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Articles

Evolution and diversification of the nuclear pore complex

Open Access
Alexandr A. Makarov, Norma E. Padilla-Mejia, Mark C. Field
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1601–1619.
https://doi.org/10.1042/BST20200570
Published: 20 July 2021
View article titled, Evolution and diversification of the nuclear pore complex
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