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Articles

Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?

Eric Rubinstein, Clotilde Théry, Pascale Zimmermann
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) BST20240523.
https://doi.org/10.1042/BST20240523
Published: 26 March 2025
View articletitled, Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?
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Articles

The emerging role of Rab proteins in osteoclast organelle biogenesis and function

Shiou-Ling Lu, Takeshi Noda
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2469–2475.
https://doi.org/10.1042/BST20240519
Published: 06 December 2024
View articletitled, The emerging role of Rab proteins in osteoclast organelle biogenesis and function
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Articles

A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway

Tekle Pauzaite, James A. Nathan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2253–2265.
https://doi.org/10.1042/BST20230861
Published: 25 November 2024
View articletitled, A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway
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Articles

The dynamic regulatory network of phosphatidic acid metabolism: a spotlight on substrate cycling between phosphatidic acid and diacylglycerol

Reika Tei
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2123–2132.
https://doi.org/10.1042/BST20231511
Published: 17 October 2024
View articletitled, The dynamic regulatory network of phosphatidic acid metabolism: a spotlight on substrate cycling between phosphatidic acid and diacylglycerol
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Articles

Biogenesis of omegasomes and autophagosomes in mammalian autophagy

Puck N. Norell, Daniele Campisi, Jagan Mohan, Thomas Wollert
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2145–2155.
https://doi.org/10.1042/BST20240015
Published: 11 October 2024
View articletitled, Biogenesis of omegasomes and autophagosomes in mammalian autophagy
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Articles

Coordinating BNIP3/NIX-mediated mitophagy in space and time

Natalie M. Niemi, Jonathan R. Friedman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 1969–1979.
https://doi.org/10.1042/BST20221364
Published: 08 October 2024
View articletitled, Coordinating BNIP3/NIX-mediated mitophagy in space and time
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Articles

The Dsc complex and its role in Golgi quality control

Yannick Weyer, David Teis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2023–2034.
https://doi.org/10.1042/BST20230375
Published: 26 September 2024
View articletitled, The Dsc complex and its role in Golgi quality control
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Articles

Mechanisms of lysosomal tubulation and sorting driven by LRRK2

Luis Bonet-Ponce, Jillian H. Kluss, Mark R. Cookson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1909–1919.
https://doi.org/10.1042/BST20240087
Published: 31 July 2024
View articletitled, Mechanisms of lysosomal tubulation and sorting driven by LRRK2
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Articles

Role of Yme1 in mitochondrial protein homeostasis: from regulation of protein import, OXPHOS function to lipid synthesis and mitochondrial dynamics

Kwan Ting Kan, Joel Wilcock, Hui Lu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1539–1548.
https://doi.org/10.1042/BST20240450
Published: 12 June 2024
View articletitled, Role of Yme1 in mitochondrial protein homeostasis: from regulation of protein import, OXPHOS function to lipid synthesis and mitochondrial dynamics
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Articles

PROPPINs and membrane fission in the endo-lysosomal system

Navin Gopaldass, Andreas Mayer
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1233–1241.
https://doi.org/10.1042/BST20230897
Published: 15 May 2024
View articletitled, PROPPINs and membrane fission in the endo-lysosomal system
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Articles

Post-translational modifications: emerging directors of cell-fate decisions during endoplasmic reticulum stress in Arabidopsis thaliana

Ethan Thibault, Federica Brandizzi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 831–848.
https://doi.org/10.1042/BST20231025
Published: 11 April 2024
View articletitled, Post-translational modifications: emerging directors of cell-fate decisions during endoplasmic reticulum stress in Arabidopsis thaliana
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Articles

How does the neuronal proteostasis network react to cellular cues?

Ki Hong Nam, Alban Ordureau
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 581–592.
https://doi.org/10.1042/BST20230316
Published: 15 March 2024
View articletitled, How does the neuronal proteostasis network react to cellular cues?
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Articles

Effects of carotenoids on mitochondrial dysfunction

Opeyemi Stella Ademowo, Olubukola Oyebode, Roshita Edward, Myra E. Conway, Helen R. Griffiths, Irundika H.K. Dias
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 65–74.
https://doi.org/10.1042/BST20230193
Published: 22 February 2024
View articletitled, Effects of carotenoids on mitochondrial dysfunction
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Articles

The PDLIM family of actin-associated proteins and their emerging role in membrane trafficking

Michael D. Healy, Brett M. Collins
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (6): 2005–2016.
https://doi.org/10.1042/BST20220804
Published: 14 December 2023
View articletitled, The PDLIM family of actin-associated proteins and their emerging role in membrane trafficking
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Articles

A tail of their own: regulation of cardiolipin and phosphatidylinositol fatty acyl profile by the acyltransferase LCLAT1

Kai Zhang, Victoria Chan, Roberto J. Botelho, Costin N. Antonescu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1765–1776.
https://doi.org/10.1042/BST20220603
Published: 22 September 2023
View articletitled, A tail of their own: regulation of cardiolipin and phosphatidylinositol fatty acyl profile by the acyltransferase LCLAT1
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Articles

Mitophagy-promoting agents and their ability to promote healthy-aging

Vijigisha Srivastava, Einav Gross
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1811–1846.
https://doi.org/10.1042/BST20221363
Published: 01 September 2023
View articletitled, Mitophagy-promoting agents and their ability to promote healthy-aging
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Articles

Mammalian cargo receptors for endoplasmic reticulum-to-Golgi transport: mechanisms and interactions

Yuan Zhang, Vishal Srivastava, Bin Zhang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 971–981.
https://doi.org/10.1042/BST20220713
Published: 19 June 2023
View articletitled, Mammalian cargo receptors for endoplasmic reticulum-to-Golgi transport: mechanisms and interactions
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Articles

The multiple ubiquitination mechanisms in CFTR peripheral quality control

Shogo Taniguchi, Ryosuke Fukuda, Tsukasa Okiyoneda
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1297–1306.
https://doi.org/10.1042/BST20221468
Published: 04 May 2023
View articletitled, The multiple ubiquitination mechanisms in CFTR peripheral quality control
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Articles

Improving the hole picture: towards a consensus on the mechanism of nuclear transport

David Cowburn, Michael Rout
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 871–886.
https://doi.org/10.1042/BST20220494
Published: 26 April 2023
View articletitled, Improving the hole picture: towards a consensus on the mechanism of nuclear transport
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Articles

The emerging roles of autophagy in intestinal epithelial cells and its links to inflammatory bowel disease

Sharon Tran, Juliani Juliani, W. Douglas Fairlie, Erinna F. Lee
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 811–826.
https://doi.org/10.1042/BST20221300
Published: 13 April 2023
View articletitled, The emerging roles of autophagy in intestinal epithelial cells and its links to inflammatory bowel disease
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Articles

Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling

Tahir Muhammad, Jian Li
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 501–512.
https://doi.org/10.1042/BST20220616
Published: 09 March 2023
View articletitled, Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling
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Articles

New discoveries in ER–mitochondria communication

Margret Helene Bülow, Julia Sellin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 571–577.
https://doi.org/10.1042/BST20221305
Published: 09 March 2023
View articletitled, New discoveries in ER–mitochondria communication
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Articles

Mitochondrial DNA in cell death and inflammation

In Collection
Cell death and survival
Rosalie Heilig, Jordan Lee, Stephen W.G. Tait
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 457–472.
https://doi.org/10.1042/BST20221525
Published: 23 February 2023
View articletitled, Mitochondrial DNA in cell death and inflammation
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Articles

The role of CaMKK2 in Golgi-associated vesicle trafficking

Grace Kennedy, Olivia Gibson, Dáire T. O'Hare, Ian G. Mills, Emma Evergren
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 331–342.
https://doi.org/10.1042/BST20220833
Published: 23 February 2023
View articletitled, The role of CaMKK2 in Golgi-associated vesicle trafficking
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Articles

The mechanisms of chromogranin B-regulated Cl − homeostasis

Qiu-Xing Jiang, Gaya Yadav
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1659–1672.
https://doi.org/10.1042/BST20220435
Published: 13 December 2022
View articletitled, The mechanisms of chromogranin B-regulated Cl − homeostasis
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Articles

Is bRaQCing bad? New roles for ribosome associated quality control factors in stress granule regulation

Noah S. Helton, Stephanie L. Moon
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1715–1724.
https://doi.org/10.1042/BST20220549
Published: 09 December 2022
View articletitled, Is bRaQCing bad? New roles for ribosome associated quality control factors in stress granule regulation
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Articles

Fundamental roles for inter-organelle communication in aging

Eric K. F. Donahue, Elizabeth M. Ruark, Kristopher Burkewitz
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1389–1402.
https://doi.org/10.1042/BST20220519
Published: 28 October 2022
View articletitled, Fundamental roles for inter-organelle communication in aging
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Articles

The functional importance of VCP to maintaining cellular protein homeostasis

Brittany A. Ahlstedt, Rakesh Ganji, Malavika Raman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1457–1469.
https://doi.org/10.1042/BST20220648
Published: 05 October 2022
View articletitled, The functional importance of VCP to maintaining cellular protein homeostasis
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Articles

The role of autophagy-lysosomal pathway in motor neuron diseases

Barbara Tedesco, Veronica Ferrari, Marta Cozzi, Marta Chierichetti, Elena Casarotto, Paola Pramaggiore, Francesco Mina, Margherita Piccolella, Riccardo Cristofani, Valeria Crippa, Paola Rusmini, Mariarita Galbiati, Angelo Poletti
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1489–1503.
https://doi.org/10.1042/BST20220778
Published: 16 September 2022
View articletitled, The role of autophagy-lysosomal pathway in motor neuron diseases
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Articles

GPX4: old lessons, new features

In Collection
Cell death and survival
Thamara Nishida Xavier da Silva, José Pedro Friedmann Angeli, Irina Ingold
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1205–1213.
https://doi.org/10.1042/BST20220682
Published: 27 June 2022
View articletitled, GPX4: old lessons, new features
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Articles

Spatial sequestration of misfolded proteins in neurodegenerative diseases

Sarah Rolli, Emily Mitchell Sontag
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 759–771.
https://doi.org/10.1042/BST20210862
Published: 21 March 2022
View articletitled, Spatial sequestration of misfolded proteins in neurodegenerative diseases
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Articles

Therapeutic targeting of mitophagy in Parkinson's disease

In Collection
Cell death and survival
Shashank Masaldan, Sylvie Callegari, Grant Dewson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 783–797.
https://doi.org/10.1042/BST20211107
Published: 21 March 2022
View articletitled, Therapeutic targeting of mitophagy in Parkinson's disease
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Articles

GCN2: roles in tumour development and progression

Lyssa T. Gold, Glenn R. Masson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 737–745.
https://doi.org/10.1042/BST20211252
Published: 21 March 2022
View articletitled, GCN2: roles in tumour development and progression
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Articles

Non-canonical roles of ATG8 for TFEB activation

In Collection
Cell death and survival
Shuhei Nakamura, Shiori Akayama, Tamotsu Yoshimori
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 47–54.
https://doi.org/10.1042/BST20210813
Published: 15 February 2022
View articletitled, Non-canonical roles of ATG8 for TFEB activation
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Articles

Molecular regulation of autophagosome formation

In Collection
Cell death and survival
Yan Hu, Fulvio Reggiori
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 55–69.
https://doi.org/10.1042/BST20210819
Published: 25 January 2022
View articletitled, Molecular regulation of autophagosome formation
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Articles

The role of caspases as executioners of apoptosis

In Collection
Cell death and survival
Sharad Kumar, Loretta Dorstyn, Yoon Lim
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 33–45.
https://doi.org/10.1042/BST20210751
Published: 23 December 2021
View articletitled, The role of caspases as executioners of apoptosis
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Articles

Non-canonical roles of autophagy proteins in endocytosis and exocytosis

In Collection
Cell death and survival
Christian Münz
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2841–2851.
https://doi.org/10.1042/BST20210811
Published: 16 November 2021
View articletitled, Non-canonical roles of autophagy proteins in endocytosis and exocytosis
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Articles

Live-cell visualization of cytochrome c : a tool to explore apoptosis

João Pessoa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2903–2915.
https://doi.org/10.1042/BST20211028
Published: 08 November 2021
View articletitled, Live-cell visualization of cytochrome c : a tool to explore apoptosis
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Articles

Primary cilium-dependent autophagy in the response to shear stress

In Collection
Cell death and survival
Etienne Morel, Nicolas Dupont, Patrice Codogno
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2831–2839.
https://doi.org/10.1042/BST20210810
Published: 08 November 2021
View articletitled, Primary cilium-dependent autophagy in the response to shear stress
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Articles

The dynamics of mitochondrial autophagy at the initiation stage

Nicholas T. Ktistakis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2199–2210.
https://doi.org/10.1042/BST20210272
Published: 19 October 2021
View articletitled, The dynamics of mitochondrial autophagy at the initiation stage
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Articles

Cellular feedback dynamics and multilevel regulation driven by the hippo pathway

Jiwon Park, Carsten Gram Hansen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1515–1527.
https://doi.org/10.1042/BST20200253
Published: 10 August 2021
View articletitled, Cellular feedback dynamics and multilevel regulation driven by the hippo pathway
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Articles

Transcriptional control of ribosome biogenesis in yeast: links to growth and stress signals

David Shore, Sevil Zencir, Benjamin Albert
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1589–1599.
https://doi.org/10.1042/BST20201136
Published: 09 July 2021
View articletitled, Transcriptional control of ribosome biogenesis in yeast: links to growth and stress signals
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Articles

The HSP70 chaperone as sensor of the NEDD8 cycle upon DNA damage

Aymeric P. Bailly, Dimitris P. Xirodimas
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1075–1083.
https://doi.org/10.1042/BST20200381
Published: 22 June 2021
View articletitled, The HSP70 chaperone as sensor of the NEDD8 cycle upon DNA damage
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Articles

Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review

Hannah Bolland, Tiffany S. Ma, Syafiq Ramlee, Kristijan Ramadan, Ester M. Hammond
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1251–1263.
https://doi.org/10.1042/BST20200861
Published: 18 May 2021
View articletitled, Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review
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Includes: Supplementary data
Articles

Musculoskeletal complications associated with pathological iron toxicity and its molecular mechanisms

Márcio Simão, M. Leonor Cancela
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 747–759.
https://doi.org/10.1042/BST20200672
Published: 30 April 2021
View articletitled, Musculoskeletal complications associated with pathological iron toxicity and its molecular mechanisms
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Articles

Phagocytic clearance of apoptotic, necrotic, necroptotic and pyroptotic cells

In Collection
Cell death and survival
Georgia K. Atkin-Smith
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 793–804.
https://doi.org/10.1042/BST20200696
Published: 12 April 2021
View articletitled, Phagocytic clearance of apoptotic, necrotic, necroptotic and pyroptotic cells
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Articles

Parkinson's disease and mitophagy: an emerging role for LRRK2

Francois Singh, Ian G. Ganley
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 551–562.
https://doi.org/10.1042/BST20190236
Published: 26 March 2021
View articletitled, Parkinson's disease and mitophagy: an emerging role for LRRK2
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Articles

It's not just a phase; ubiquitination in cytosolic protein quality control

Heather A. Baker, Jonathan P. Bernardini
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 365–377.
https://doi.org/10.1042/BST20200694
Published: 26 February 2021
View articletitled, It's not just a phase; ubiquitination in cytosolic protein quality control
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Articles

Galectin-8, cytokines, and the storm

Yehiel Zick
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 135–149.
https://doi.org/10.1042/BST20200677
Published: 11 January 2021
View articletitled, Galectin-8, cytokines, and the storm
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Articles

The role of AP-4 in cargo export from the trans -Golgi network and hereditary spastic paraplegia

Rafael Mattera, Raffaella De Pace, Juan S. Bonifacino
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 1877–1888.
https://doi.org/10.1042/BST20190664
Published: 21 October 2020
View articletitled, The role of AP-4 in cargo export from the trans -Golgi network and hereditary spastic paraplegia
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Includes: Multimedia, Supplementary data