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Articles

Advances towards potential cancer therapeutics targeting Hippo signaling

Rui Zhu, Zhihan Jiao, Fa-Xing Yu

Biochem Soc Trans (2024) BST20240244.

https://doi.org/10.1042/BST20240244

Published: 06 December 2024

View article titled, Advances towards potential cancer therapeutics targeting Hippo signaling

Articles

Beyond expectations: the development and biological activity of cytokinin oxidase/dehydrogenase inhibitors

Jaroslav Nisler

Biochem Soc Trans (2024) BST20231561.

https://doi.org/10.1042/BST20231561

Published: 07 November 2024

View article titled, Beyond expectations: the development and biological activity of cytokinin oxidase/dehydrogenase inhibitors

Articles

Hetero-oligomeric interaction as a new regulatory mechanism for protein arginine methyltransferases

Angela A. Bae, Y. George Zheng

Biochem Soc Trans (2024) 52 (5): 2193–2201.

https://doi.org/10.1042/BST20240242

Published: 26 September 2024

View article titled, Hetero-oligomeric interaction as a new regulatory mechanism for protein arginine methyltransferases

Articles

Mechanisms conferring bacterial cell wall variability and adaptivity

Gabriel Torrens, Felipe Cava

Biochem Soc Trans (2024) 52 (5): 1981–1993.

https://doi.org/10.1042/BST20230027

Published: 26 September 2024

View article titled, Mechanisms conferring bacterial cell wall variability and adaptivity

Articles

Discovery of telomerase inhibitors: existing strategies and emerging innovations

Lauren Kageler, Elisa Aquilanti

Biochem Soc Trans (2024) 52 (4): 1957–1968.

https://doi.org/10.1042/BST20230264

Published: 28 August 2024

View article titled, Discovery of telomerase inhibitors: existing strategies and emerging innovations

Articles

Understanding pyrethrin biosynthesis: toward and beyond natural pesticide overproduction

Kazuhiko Matsuda

Biochem Soc Trans (2024) 52 (4): 1927–1937.

https://doi.org/10.1042/BST20240213

Published: 13 August 2024

View article titled, Understanding pyrethrin biosynthesis: toward and beyond natural pesticide overproduction

Articles

Lessons from natural molecular glue degraders

Shiyun Cao

Biochem Soc Trans (2024) 52 (3): 1191–1197.

https://doi.org/10.1042/BST20230836

Published: 12 June 2024

View article titled, Lessons from natural molecular glue degraders

Articles

The high-affinity tryptophan uptake transport system in human cells

Keisuke Wakasugi, Takumi Yokosawa

Biochem Soc Trans (2024) 52 (3): 1149–1158.

https://doi.org/10.1042/BST20230742

Published: 30 May 2024

View article titled, The high-affinity tryptophan uptake transport system in human cells

Articles

RNA m 6 A modification, signals for degradation or stabilisation?

Guifeng Wei

Biochem Soc Trans (2024) 52 (2): 707–717.

https://doi.org/10.1042/BST20230574

Published: 17 April 2024

View article titled, RNA m 6 A modification, signals for degradation or stabilisation?

Articles

Covalent activity-based probes for imaging of serine proteases

Marcin Skorenski, Shanping Ji, Steven H. L. Verhelst

Biochem Soc Trans (2024) 52 (2): 923–935.

https://doi.org/10.1042/BST20231450

Published: 17 April 2024

View article titled, Covalent activity-based probes for imaging of serine proteases

Articles

The role of lipids in genome integrity and pluripotency

Qiyu Tian, Hoyoung Chung, Duancheng Wen

Biochem Soc Trans (2024) 52 (2): 639–650.

https://doi.org/10.1042/BST20230479

Published: 20 March 2024

View article titled, The role of lipids in genome integrity and pluripotency

Articles

Backbone interactions and secondary structures in phase separation of disordered proteins

Shanlong Li, Yumeng Zhang, Jianhan Chen

Biochem Soc Trans (2024) 52 (1): 319–329.

https://doi.org/10.1042/BST20230618

Published: 13 February 2024

View article titled, Backbone interactions and secondary structures in phase separation of disordered proteins

Articles

CRISPR-controlled proteases

Sam P. B. van Beljouw, Stan J. J. Brouns

Biochem Soc Trans (2024) 52 (1): 441–453.

https://doi.org/10.1042/BST20230962

Published: 09 February 2024

View article titled, CRISPR-controlled proteases

Articles

Revealing chromatin-specific functions of histone deacylases

In Collection

Epigenetics

Carlos Moreno-Yruela, Beat Fierz

Biochem Soc Trans (2024) 52 (1): 353–365.

https://doi.org/10.1042/BST20230693

Published: 08 January 2024

View article titled, Revealing chromatin-specific functions of histone deacylases

Articles

Mechanisms of stress management in mitochondrial protein import

Maryam Mukhtar, Krutika Thakkur, Agnieszka Chacinska, Piotr Bragoszewski

Biochem Soc Trans (2023) 51 (6): 2117–2126.

https://doi.org/10.1042/BST20230377

Published: 21 November 2023

View article titled, Mechanisms of stress management in mitochondrial protein import

Articles

The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production

Eduardo Fuentes-Lemus, Juan Sebastián Reyes, Juan David Figueroa, Michael J. Davies, Camilo López-Alarcón

Biochem Soc Trans (2023) 51 (6): 2173–2187.

https://doi.org/10.1042/BST20231027

Published: 16 November 2023

View article titled, The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production

Articles

Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion

Chris Greening, Ashleigh Kropp, Kylie Vincent, Rhys Grinter

Biochem Soc Trans (2023) 51 (5): 1921–1933.

https://doi.org/10.1042/BST20230120

Published: 25 September 2023

View article titled, Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion

Articles

Insights into the function of cytoglobin

Brandon J. Reeder

Biochem Soc Trans (2023) 51 (5): 1907–1919.

https://doi.org/10.1042/BST20230081

Published: 18 September 2023

View article titled, Insights into the function of cytoglobin

Articles

Mitophagy-promoting agents and their ability to promote healthy-aging

Vijigisha Srivastava, Einav Gross

Biochem Soc Trans (2023) 51 (5): 1811–1846.

https://doi.org/10.1042/BST20221363

Published: 01 September 2023

View article titled, Mitophagy-promoting agents and their ability to promote healthy-aging

Articles

Maximizing the performance of protein-based fluorescent biosensors

Fu Chai, Dazhou Cheng, Yusuke Nasu, Takuya Terai, Robert E. Campbell

Biochem Soc Trans (2023) 51 (4): 1585–1595.

https://doi.org/10.1042/BST20221413

Published: 11 July 2023

View article titled, Maximizing the performance of protein-based fluorescent biosensors

Articles

Biomimetic engineering of nonribosomal peptide synthesis

Kexin Zhang, Hajo Kries

Biochem Soc Trans (2023) 51 (4): 1521–1532.

https://doi.org/10.1042/BST20221264

Published: 06 July 2023

View article titled, Biomimetic engineering of nonribosomal peptide synthesis

Articles

Mapping lipid pathways during phagocytosis

Ojal Saharan, Siddhesh S. Kamat

Biochem Soc Trans (2023) 51 (3): 1279–1287.

https://doi.org/10.1042/BST20221424

Published: 14 June 2023

View article titled, Mapping lipid pathways during phagocytosis

Articles

Small molecule and peptide inhibitors of βTrCP and the βTrCP–NRF2 protein–protein interaction

Uzma Jaffry, Geoff Wells

Biochem Soc Trans (2023) 51 (3): 925–936.

https://doi.org/10.1042/BST20220352

Published: 09 June 2023

View article titled, Small molecule and peptide inhibitors of βTrCP and the βTrCP–NRF2 protein–protein interaction

Articles

Chemical labeling and proteomics for characterization of unannotated small and alternative open reading frame-encoded polypeptides

Yanran Chen, Xiongwen Cao, Ken H. Loh, Sarah A. Slavoff

Biochem Soc Trans (2023) 51 (3): 1071–1082.

https://doi.org/10.1042/BST20221074

Published: 12 May 2023

View article titled, Chemical labeling and proteomics for characterization of unannotated small and alternative open reading frame-encoded polypeptides

Articles

Eliminating oncogenic RAS: back to the future at the drawing board

Candy Laura Steffen, Pelin Kaya, Elisabeth Schaffner-Reckinger, Daniel Abankwa

Biochem Soc Trans (2023) 51 (1): 447–456.

https://doi.org/10.1042/BST20221343

Published: 23 January 2023

View article titled, Eliminating oncogenic RAS: back to the future at the drawing board

Includes: Supplementary data

Articles

Therapeutic targeting of eukaryotic initiation factor (eIF) 4E

Jerry Pelletier, Nahum Sonenberg

Biochem Soc Trans (2023) 51 (1): 113–124.

https://doi.org/10.1042/BST20220285

Published: 20 January 2023

View article titled, Therapeutic targeting of eukaryotic initiation factor (eIF) 4E

Articles

G4-interacting proteins endangering genomic stability at G4 DNA-forming sites

Nayun Kim

Biochem Soc Trans (2023) 51 (1): 403–413.

https://doi.org/10.1042/BST20221018

Published: 11 January 2023

View article titled, G4-interacting proteins endangering genomic stability at G4 DNA-forming sites

Articles

Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery

Lionel Urán Landaburu, Mercedes Didier Garnham, Fernán Agüero

Biochem Soc Trans (2023) 51 (1): 195–206.

https://doi.org/10.1042/BST20220618

Published: 06 January 2023

View article titled, Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery

Articles

Interactions governing transcriptional activity of nuclear receptors

Sabab Hasan Khan, C. Denise Okafor

Biochem Soc Trans (2022) 50 (6): 1941–1952.

https://doi.org/10.1042/BST20220338

Published: 16 December 2022

View article titled, Interactions governing transcriptional activity of nuclear receptors

Articles

LncRNA: a new perspective on the study of neurological diseases

Yun Ma, Siqi He, Tianhe Gu, Yixuan Liu, Shuya He, Zhisheng Jiang

Biochem Soc Trans (2022) 50 (2): 951–963.

https://doi.org/10.1042/BST20211181

Published: 06 April 2022

View article titled, LncRNA: a new perspective on the study of neurological diseases

Articles

Cofactor F 420 , an emerging redox power in biosynthesis of secondary metabolites

Ghader Bashiri

Biochem Soc Trans (2022) 50 (1): 253–267.

https://doi.org/10.1042/BST20211286

Published: 22 February 2022

View article titled, Cofactor F 420 , an emerging redox power in biosynthesis of secondary metabolites

Articles

Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Jorge Ripoll-Rozada, Joshua W. C. Maxwell, Richard J. Payne, Pedro José Barbosa Pereira

Biochem Soc Trans (2022) 50 (1): 387–401.

https://doi.org/10.1042/BST20210600

Published: 07 January 2022

View article titled, Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Articles

Writing and erasing O- GlcNAc from target proteins in cells

Yun Ge, Christina M. Woo

Biochem Soc Trans (2021) 49 (6): 2891–2901.

https://doi.org/10.1042/BST20210865

Published: 16 November 2021

View article titled, Writing and erasing O- GlcNAc from target proteins in cells

Articles

Live-cell visualization of cytochrome c : a tool to explore apoptosis

João Pessoa

Biochem Soc Trans (2021) 49 (6): 2903–2915.

https://doi.org/10.1042/BST20211028

Published: 08 November 2021

View article titled, Live-cell visualization of cytochrome c : a tool to explore apoptosis

Articles

Structural insights into glucocorticoid receptor function

Filipp Frank, Eric A. Ortlund, Xu Liu

Biochem Soc Trans (2021) 49 (5): 2333–2343.

https://doi.org/10.1042/BST20210419

Published: 28 October 2021

View article titled, Structural insights into glucocorticoid receptor function

Articles

Chemical biology approaches to study histone interactors

Antony J. Burton, Ghaith M. Hamza, Andrew X. Zhang, Tom W. Muir

Biochem Soc Trans (2021) 49 (5): 2431–2441.

https://doi.org/10.1042/BST20210772

Published: 28 October 2021

View article titled, Chemical biology approaches to study histone interactors

Articles

Controlled metabolic cascades for protein synthesis in an artificial cell

Huong Thanh Nguyen, Sungwoo Lee, Kwanwoo Shin

Biochem Soc Trans (2021) 49 (5): 2143–2151.

https://doi.org/10.1042/BST20210175

Published: 08 October 2021

View article titled, Controlled metabolic cascades for protein synthesis in an artificial cell

Articles

The pockets guide to HLA class I molecules

Andrea T. Nguyen, Christopher Szeto, Stephanie Gras

Biochem Soc Trans (2021) 49 (5): 2319–2331.

https://doi.org/10.1042/BST20210410

Published: 28 September 2021

View article titled, The pockets guide to HLA class I molecules

Articles

Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer

In Collection

Cell death and survival

Erinna F. Lee, W. Douglas Fairlie

Biochem Soc Trans (2021) 49 (5): 2381–2395.

https://doi.org/10.1042/BST20210749

Published: 13 September 2021

View article titled, Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer

Articles

Semi- and fully synthetic carbohydrate vaccines against pathogenic bacteria: recent developments

Magdalena E. Zasłona, A. Michael Downey, Peter H. Seeberger, Oren Moscovitz

Biochem Soc Trans (2021) 49 (5): 2411–2429.

https://doi.org/10.1042/BST20210766

Published: 08 September 2021

View article titled, Semi- and fully synthetic carbohydrate vaccines against pathogenic bacteria: recent developments

Articles

Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Aaron D. Krabill, Zhong-Yin Zhang

Biochem Soc Trans (2021) 49 (4): 1723–1734.

https://doi.org/10.1042/BST20201308

Published: 25 August 2021

View article titled, Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Articles

Exploring chromatin structural roles of non-coding RNAs at imprinted domains

David Llères, Yui Imaizumi, Robert Feil

Biochem Soc Trans (2021) 49 (4): 1867–1879.

https://doi.org/10.1042/BST20210758

Published: 02 August 2021

View article titled, Exploring chromatin structural roles of non-coding RNAs at imprinted domains

Articles

Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry

Luke A. Clifton

Biochem Soc Trans (2021) 49 (4): 1537–1546.

https://doi.org/10.1042/BST20201071

Published: 09 July 2021

View article titled, Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry

Articles

Progress in the therapeutic inhibition of Cdc42 signalling

Natasha P. Murphy, Helen R. Mott, Darerca Owen

Biochem Soc Trans (2021) 49 (3): 1443–1456.

https://doi.org/10.1042/BST20210112

Published: 08 June 2021

View article titled, Progress in the therapeutic inhibition of Cdc42 signalling

Articles

Chemical reporters to study mammalian O-glycosylation

Kathryn E. Huxley, Lianne I. Willems

Biochem Soc Trans (2021) 49 (2): 903–913.

https://doi.org/10.1042/BST20200839

Published: 16 April 2021

View article titled, Chemical reporters to study mammalian O-glycosylation

Articles

Combinatorial biosynthesis for the generation of new-to-nature peptide antimicrobials

Fleur Ruijne, Oscar P. Kuipers

Biochem Soc Trans (2021) 49 (1): 203–215.

https://doi.org/10.1042/BST20200425

Published: 13 January 2021

View article titled, Combinatorial biosynthesis for the generation of new-to-nature peptide antimicrobials

Articles

Inhibition of RAF dimers: it takes two to tango

Frazer A. Cook, Simon J. Cook

Biochem Soc Trans (2021) 49 (1): 237–251.

https://doi.org/10.1042/BST20200485

Published: 24 December 2020

View article titled, Inhibition of RAF dimers: it takes two to tango

Articles

Protein–membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies

Agata Nawrotek, Mahel Zeghouf, Jacqueline Cherfils

Biochem Soc Trans (2020) 48 (6): 2721–2728.

https://doi.org/10.1042/BST20200482

Published: 18 December 2020

View article titled, Protein–membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies

Articles

Multifunctionality of F-rich nucleoporins

Nike Heinß, Mikhail Sushkin, Miao Yu, Edward A. Lemke

Biochem Soc Trans (2020) 48 (6): 2603–2614.

https://doi.org/10.1042/BST20200357

Published: 18 December 2020

View article titled, Multifunctionality of F-rich nucleoporins

Articles

Engineering with NanoLuc: a playground for the development of bioluminescent protein switches and sensors

Lieuwe Biewenga, Bas J.H.M. Rosier, Maarten Merkx

Biochem Soc Trans (2020) 48 (6): 2643–2655.

https://doi.org/10.1042/BST20200440

Published: 26 November 2020

View article titled, Engineering with NanoLuc: a playground for the development of bioluminescent protein switches and sensors

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