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Articles

‘Where is my gap’: mechanisms underpinning PARP inhibitor sensitivity in cancer

Lauryn Buckley-Benbow, Alessandro Agnarelli, Roberto Bellelli

Biochem Soc Trans (2025) BST20241633.

https://doi.org/10.1042/BST20241633

Published: 10 February 2025

View article titled, ‘Where is my gap’: mechanisms underpinning PARP inhibitor sensitivity in cancer

Articles

Polymer models of chromatin organization in virally infected cells

Andrea Fontana, Fabrizio Tafuri, Alex Abraham, Simona Bianco, Andrea Esposito, Mattia Conte, Francesca Vercellone, Florinda Di Pierno, Sougata Guha, Ciro Di Carluccio, Andrea M. Chiariello

Biochem Soc Trans (2025) BST20240598.

https://doi.org/10.1042/BST20240598

Published: 07 February 2025

View article titled, Polymer models of chromatin organization in virally infected cells

Articles

The role of transcription bodies in gene expression: what embryos teach us

Martino Ugolini, Nadine L. Vastenhouw

Biochem Soc Trans (2025) BST20240599.

https://doi.org/10.1042/BST20240599

Published: 06 February 2025

View article titled, The role of transcription bodies in gene expression: what embryos teach us

Articles

Microscopy methods for the in vivo study of nanoscale nuclear organization

Nidhi Rani Lokesh, Mark E. Pownall

Biochem Soc Trans (2025) BST20240629.

https://doi.org/10.1042/BST20240629

Published: 03 February 2025

View article titled, Microscopy methods for the in vivo study of nanoscale nuclear organization

Articles

Beyond the mono-nucleosome

Juliana Kikumoto Dias, Sheena D’Arcy

Biochem Soc Trans (2025) BST20230721.

https://doi.org/10.1042/BST20230721

Published: 31 January 2025

View article titled, Beyond the mono-nucleosome

Articles

Chromosome hitchhiking: a potential strategy adopted by the selfish yeast plasmids to ensure symmetric inheritance during cell division

Deepanshu Kumar, Santanu Kumar Ghosh

Biochem Soc Trans (2024) 52 (6): 2359–2372.

https://doi.org/10.1042/BST20231555

Published: 13 December 2024

View article titled, Chromosome hitchhiking: a potential strategy adopted by the selfish yeast plasmids to ensure symmetric inheritance during cell division

Articles

Adding a twist to the loops: the role of DNA superhelicity in the organization of chromosomes by SMC protein complexes

Antonio Valdés, Christian H. Haering

Biochem Soc Trans (2024) 52 (6): 2487–2497.

https://doi.org/10.1042/BST20240650

Published: 10 December 2024

View article titled, Adding a twist to the loops: the role of DNA superhelicity in the organization of chromosomes by SMC protein complexes

Articles

Untangling bacterial DNA topoisomerases functions

Céline Borde, Lisa Bruno, Olivier Espéli

Biochem Soc Trans (2024) 52 (6): 2321–2331.

https://doi.org/10.1042/BST20240089

Published: 07 November 2024

View article titled, Untangling bacterial DNA topoisomerases functions

Articles

Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction

Sneha S. Varghese, Alessandro Giovanni Hernandez-De La Peña, Sangeeta Dhawan

Biochem Soc Trans (2024) 52 (5): 2133–2144.

https://doi.org/10.1042/BST20231519

Published: 04 October 2024

View article titled, Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction

Articles

Histone H3 mutations and their impact on genome stability maintenance

Lucas D. Caeiro, Ramiro E. Verdun, Lluis Morey

Biochem Soc Trans (2024) 52 (5): 2179–2191.

https://doi.org/10.1042/BST20240177

Published: 09 September 2024

View article titled, Histone H3 mutations and their impact on genome stability maintenance

Articles

Non-Mendelian transmission of X chromosomes: mechanisms and impact on sex ratios and population dynamics in different breeding systems

Sally Adams, Andre Pires-daSilva

Biochem Soc Trans (2024) 52 (4): 1777–1784.

https://doi.org/10.1042/BST20231411

Published: 16 August 2024

View article titled, Non-Mendelian transmission of X chromosomes: mechanisms and impact on sex ratios and population dynamics in different breeding systems

Articles

Structural biology of shelterin and telomeric chromatin: the pieces and an unfinished puzzle

Hongmiao Hu, Helen Linwen Yan, Thi Hoang Duong Nguyen

Biochem Soc Trans (2024) 52 (4): 1551–1564.

https://doi.org/10.1042/BST20230300

Published: 07 August 2024

View article titled, Structural biology of shelterin and telomeric chromatin: the pieces and an unfinished puzzle

Articles

Nuclear RNA: a transcription-dependent regulator of chromatin structure

Jon Stocks, Nick Gilbert

Biochem Soc Trans (2024) 52 (4): 1605–1615.

https://doi.org/10.1042/BST20230787

Published: 31 July 2024

View article titled, Nuclear RNA: a transcription-dependent regulator of chromatin structure

Articles

The initiation of mitochondrial DNA replication

Yi Liu, Haibin Liu, Fan Zhang, Hong Xu

Biochem Soc Trans (2024) 52 (3): 1243–1251.

https://doi.org/10.1042/BST20230952

Published: 17 June 2024

View article titled, The initiation of mitochondrial DNA replication

Articles

Nucleosomal asymmetry: a novel mechanism to regulate nucleosome function

In Collection

Epigenetics

Devisree Valsakumar, Philipp Voigt

Biochem Soc Trans (2024) 52 (3): 1219–1232.

https://doi.org/10.1042/BST20230877

Published: 23 May 2024

View article titled, Nucleosomal asymmetry: a novel mechanism to regulate nucleosome function

Articles

Differential 3D genome architecture and imprinted gene expression: cause or consequence?

Benoit Moindrot, Yui Imaizumi, Robert Feil

Biochem Soc Trans (2024) 52 (3): 973–986.

https://doi.org/10.1042/BST20230143

Published: 22 May 2024

View article titled, Differential 3D genome architecture and imprinted gene expression: cause or consequence?

Articles

Retrotransposons in embryogenesis and neurodevelopment

Mary Jo Talley, Michelle S. Longworth

Biochem Soc Trans (2024) 52 (3): 1159–1171.

https://doi.org/10.1042/BST20230757

Published: 08 May 2024

View article titled, Retrotransposons in embryogenesis and neurodevelopment

Articles

The choreography of chromatin in RNA polymerase III regulation

Maria Elize van Breugel, Alan Gerber, Fred van Leeuwen

Biochem Soc Trans (2024) 52 (3): 1173–1189.

https://doi.org/10.1042/BST20230770

Published: 26 April 2024

View article titled, The choreography of chromatin in RNA polymerase III regulation

Articles

SUMO and the DNA damage response

Jai S. Bhachoo, Alexander J. Garvin

Biochem Soc Trans (2024) 52 (2): 773–792.

https://doi.org/10.1042/BST20230862

Published: 17 April 2024

View article titled, SUMO and the DNA damage response

Articles

Deconstructing cancer with precision genome editing

Grace A. Johnson, Samuel I. Gould, Francisco J. Sánchez-Rivera

Biochem Soc Trans (2024) 52 (2): 803–819.

https://doi.org/10.1042/BST20230984

Published: 17 April 2024

View article titled, Deconstructing cancer with precision genome editing

Articles

The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development

Dhurjhoti Saha, Srinivas Animireddy, Blaine Bartholomew

Biochem Soc Trans (2024) 52 (2): 603–616.

https://doi.org/10.1042/BST20230416

Published: 04 April 2024

View article titled, The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development

Articles

A dynamic role for transcription factors in restoring transcription through mitosis

Marek A. Budzyński, Alexander K.L. Wong, Armin Faghihi, Sheila S. Teves

Biochem Soc Trans (2024) 52 (2): 821–830.

https://doi.org/10.1042/BST20231022

Published: 25 March 2024

View article titled, A dynamic role for transcription factors in restoring transcription through mitosis

Articles

Genome organization across scales: mechanistic insights from in vitro reconstitution studies

In Collection

Epigenetics

Elisa Oberbeckmann, A. Marieke Oudelaar

Biochem Soc Trans (2024) 52 (2): 793–802.

https://doi.org/10.1042/BST20230883

Published: 07 March 2024

View article titled, Genome organization across scales: mechanistic insights from in vitro reconstitution studies

Articles

Bivalent chromatin: a developmental balancing act tipped in cancer

In Collection

Epigenetics

Eleanor Glancy, Natalie Choy, Melanie A. Eckersley-Maslin

Biochem Soc Trans (2024) 52 (1): 217–229.

https://doi.org/10.1042/BST20230426

Published: 22 February 2024

View article titled, Bivalent chromatin: a developmental balancing act tipped in cancer

Articles

Transcriptional repression across mitosis: mechanisms and functions

A. Contreras, C. Perea-Resa

Biochem Soc Trans (2024) 52 (1): 455–464.

https://doi.org/10.1042/BST20231071

Published: 19 February 2024

View article titled, Transcriptional repression across mitosis: mechanisms and functions

Articles

DDX41: exploring the roles of a versatile helicase

Lacey Winstone, Yohan Jung, Yuliang Wu

Biochem Soc Trans (2024) 52 (1): 395–405.

https://doi.org/10.1042/BST20230725

Published: 13 February 2024

View article titled, DDX41: exploring the roles of a versatile helicase

Articles

The molecular machinery of meiotic recombination

Linda Chen, John R. Weir

Biochem Soc Trans (2024) 52 (1): 379–393.

https://doi.org/10.1042/BST20230712

Published: 13 February 2024

View article titled, The molecular machinery of meiotic recombination

Articles

Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin

In Collection

Epigenetics

Peter B. Becker

Biochem Soc Trans (2024) 52 (1): 423–429.

https://doi.org/10.1042/BST20230878

Published: 08 February 2024

View article titled, Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin

Articles

All who wander are not lost: the search for homology during homologous recombination

Jingyi Hu, J. Brooks Crickard

Biochem Soc Trans (2024) 52 (1): 367–377.

https://doi.org/10.1042/BST20230705

Published: 07 February 2024

View article titled, All who wander are not lost: the search for homology during homologous recombination

Articles

Kinetochore–microtubule error correction for biorientation: lessons from yeast

Shuyu Li, Taciana Kasciukovic, Tomoyuki U. Tanaka

Biochem Soc Trans (2024) 52 (1): 29–39.

https://doi.org/10.1042/BST20221261

Published: 02 February 2024

View article titled, Kinetochore–microtubule error correction for biorientation: lessons from yeast

Articles

Advances in understanding telomerase assembly

Basma M. Klump, Jens C. Schmidt

Biochem Soc Trans (2023) 51 (6): 2093–2101.

https://doi.org/10.1042/BST20230269

Published: 18 December 2023

View article titled, Advances in understanding telomerase assembly

Articles

The MYBL1/TCFL5 transcription network: two collaborative factors with central role in male meiosis

Martin Säflund, Deniz M. Özata

Biochem Soc Trans (2023) 51 (6): 2163–2172.

https://doi.org/10.1042/BST20231007

Published: 28 November 2023

View article titled, The MYBL1/TCFL5 transcription network: two collaborative factors with central role in male meiosis

Articles

Current working models of SMC-driven DNA-loop extrusion

Kyoung-Wook Moon, Je-Kyung Ryu

Biochem Soc Trans (2023) 51 (5): 1801–1810.

https://doi.org/10.1042/BST20220898

Published: 28 September 2023

View article titled, Current working models of SMC-driven DNA-loop extrusion

Articles

ALTercations at telomeres: stress, recombination and extrachromosomal affairs

Taylor K Loe, Eros Lazzerini Denchi, Gianna M. Tricola, Benura Azeroglu

Biochem Soc Trans (2023) 51 (5): 1935–1946.

https://doi.org/10.1042/BST20230265

Published: 28 September 2023

View article titled, ALTercations at telomeres: stress, recombination and extrachromosomal affairs

Articles

Histone mutations in cancer

Kimberly N. Espinoza Pereira, Jixiu Shan, Jonathan D. Licht, Richard L. Bennett

Biochem Soc Trans (2023) 51 (5): 1749–1763.

https://doi.org/10.1042/BST20210567

Published: 18 September 2023

View article titled, Histone mutations in cancer

Articles

SMC-based immunity against extrachromosomal DNA elements

Hon Wing Liu, Florian Roisné-Hamelin, Stephan Gruber

Biochem Soc Trans (2023) 51 (4): 1571–1583.

https://doi.org/10.1042/BST20221395

Published: 16 August 2023

View article titled, SMC-based immunity against extrachromosomal DNA elements

Articles

Myosin in chromosome organisation and gene expression

Isabel W. Shahid-Fuente, Christopher P. Toseland

Biochem Soc Trans (2023) 51 (3): 1023–1034.

https://doi.org/10.1042/BST20220939

Published: 12 May 2023

View article titled, Myosin in chromosome organisation and gene expression

Articles

Studying histone inheritance in different systems using imaging-based methods and perspectives

Emily Zion, Xin Chen

Biochem Soc Trans (2023) 51 (3): 1035–1046.

https://doi.org/10.1042/BST20220983

Published: 12 May 2023

View article titled, Studying histone inheritance in different systems using imaging-based methods and perspectives

Articles

The function and regulation of ADP-ribosylation in the DNA damage response

Lena Duma, Ivan Ahel

Biochem Soc Trans (2023) 51 (3): 995–1008.

https://doi.org/10.1042/BST20220749

Published: 12 May 2023

View article titled, The function and regulation of ADP-ribosylation in the DNA damage response

Articles

The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication

Yuki Hatoyama, Masato T. Kanemaki

Biochem Soc Trans (2023) 51 (3): 1289–1295.

https://doi.org/10.1042/BST20221465

Published: 05 May 2023

View article titled, The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication

Articles

The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?

Chloe Girard, David Zwicker, Raphael Mercier

Biochem Soc Trans (2023) 51 (3): 1179–1190.

https://doi.org/10.1042/BST20221329

Published: 05 May 2023

View article titled, The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?

Includes: Multimedia, Supplementary data

Articles

Mre11–Rad50: the DNA end game

Karl-Peter Hopfner

Biochem Soc Trans (2023) 51 (2): 527–538.

https://doi.org/10.1042/BST20220754

Published: 09 March 2023

View article titled, Mre11–Rad50: the DNA end game

Articles

Structural insights on the KMT2–NCP interaction

Zi Yang, Robert Zepeda, Yali Dou

Biochem Soc Trans (2023) 51 (1): 427–434.

https://doi.org/10.1042/BST20221155

Published: 25 January 2023

View article titled, Structural insights on the KMT2–NCP interaction

Articles

G4-interacting proteins endangering genomic stability at G4 DNA-forming sites

Nayun Kim

Biochem Soc Trans (2023) 51 (1): 403–413.

https://doi.org/10.1042/BST20221018

Published: 11 January 2023

View article titled, G4-interacting proteins endangering genomic stability at G4 DNA-forming sites

Articles

Form and function of archaeal genomes

Stephen D. Bell

Biochem Soc Trans (2022) 50 (6): 1931–1939.

https://doi.org/10.1042/BST20221396

Published: 13 December 2022

View article titled, Form and function of archaeal genomes

Articles

The influence of high-order chromatin state in the regulation of stem cell fate

Xinpeng Chen, Haiyan Lin, Guohong Li

Biochem Soc Trans (2022) 50 (6): 1809–1822.

https://doi.org/10.1042/BST20220763

Published: 09 December 2022

View article titled, The influence of high-order chromatin state in the regulation of stem cell fate

Articles

The remodeling of Z-DNA in the mammalian germ line

Yingying Meng, Piroska E. Szabó

Biochem Soc Trans (2022) 50 (6): 1875–1884.

https://doi.org/10.1042/BST20221015

Published: 01 December 2022

View article titled, The remodeling of Z-DNA in the mammalian germ line

Articles

Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance

Lauren T. Pecorino, Roel G.W. Verhaak, Anton Henssen, Paul S. Mischel

Biochem Soc Trans (2022) 50 (6): 1911–1920.

https://doi.org/10.1042/BST20221045

Published: 10 November 2022

View article titled, Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance

Articles

Unveiling dynamic enhancer–promoter interactions in Drosophila melanogaster

Hao Deng, Gaochen Jin, Bomyi Lim

Biochem Soc Trans (2022) 50 (6): 1633–1642.

https://doi.org/10.1042/BST20220325

Published: 09 November 2022

View article titled, Unveiling dynamic enhancer–promoter interactions in Drosophila melanogaster

Articles

Regulation of ATR–CHK1 signaling by ubiquitination of CLASPIN

Xuefei Zhu, Xiang-Yang Zheng, Peng Gong, Xingzhi Xu

Biochem Soc Trans (2022) 50 (5): 1471–1480.

https://doi.org/10.1042/BST20220729

Published: 05 October 2022

View article titled, Regulation of ATR–CHK1 signaling by ubiquitination of CLASPIN

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