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Articles

Ceramide homeostasis in hepatic lipid droplets

Open Access
Leobarda Robles-Martinez, Kylie H. Morin, Mariana Nikolova-Karakashian
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (02): 509–518.
https://doi.org/10.1042/BST20253042
Published: 18 April 2025
View articletitled, Ceramide homeostasis in hepatic lipid droplets
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Articles

The role of protein O-GlcNAcylation in diabetic cardiomyopathy

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John C. Chatham, Adam R. Wende
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2343–2358.
https://doi.org/10.1042/BST20240262
Published: 27 November 2024
View articletitled, The role of protein O-GlcNAcylation in diabetic cardiomyopathy
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Articles

Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction

Open Access
Sneha S. Varghese, Alessandro Giovanni Hernandez-De La Peña, Sangeeta Dhawan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2133–2144.
https://doi.org/10.1042/BST20231519
Published: 04 October 2024
View articletitled, Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction
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Articles

Structure, function, and lipid sensing activity in the thioesterase superfamily

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Molly Little, Eric A. Ortlund
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1565–1577.
https://doi.org/10.1042/BST20230313
Published: 14 August 2024
View articletitled, Structure, function, and lipid sensing activity in the thioesterase superfamily
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Articles

Ceramide microdomains: the major influencers of the sphingolipid media platform

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Mariah Weber-Stout, Rebekah J. Nicholson, Carlos Dave C. Dumaguit, William L. Holland, Scott A. Summers
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1765–1776.
https://doi.org/10.1042/BST20231395
Published: 31 July 2024
View articletitled, Ceramide microdomains: the major influencers of the sphingolipid media platform
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Articles

Insulin signalling and GLUT4 trafficking in insulin resistance

Open Access
Julian van Gerwen, Amber S. Shun-Shion, Daniel J. Fazakerley
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1057–1069.
https://doi.org/10.1042/BST20221066
Published: 30 May 2023
View articletitled, Insulin signalling and GLUT4 trafficking in insulin resistance
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Articles

Loss of brain energy metabolism control as a driver for memory impairment upon insulin resistance

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João M. N. Duarte
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 287–301.
https://doi.org/10.1042/BST20220789
Published: 06 January 2023
View articletitled, Loss of brain energy metabolism control as a driver for memory impairment upon insulin resistance
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Articles

Placental extracellular vesicles in maternal-fetal communication during pregnancy

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Charlène Martin, Mathilde Bergamelli, Cécile E. Malnou, Gisela D'Angelo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1785–1795.
https://doi.org/10.1042/BST20220734
Published: 09 December 2022
View articletitled, Placental extracellular vesicles in maternal-fetal communication during pregnancy
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Articles

Circadian rhythm of lipid metabolism

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Flore Sinturel, Weronika Spaleniak, Charna Dibner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1191–1204.
https://doi.org/10.1042/BST20210508
Published: 23 May 2022
View articletitled, Circadian rhythm of lipid metabolism
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Articles

Host gene effects on gut microbiota in type 1 diabetes

Open Access
Keyu Guo, Juan Huang, Zhiguang Zhou
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1133–1142.
https://doi.org/10.1042/BST20220004
Published: 06 May 2022
View articletitled, Host gene effects on gut microbiota in type 1 diabetes
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Articles

Role of macronutrient intake in the epigenetics of obesity

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Priyadarshni Patel, Jeganathan Ramesh Babu, Xu Wang, Thangiah Geetha
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 487–497.
https://doi.org/10.1042/BST20211069
Published: 07 January 2022
View articletitled, Role of macronutrient intake in the epigenetics of obesity
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Articles

Current understanding of the role of microRNAs from adipose-derived extracellular vesicles in obesity

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Le Zhao, Haili Yang, Xingchun Li, Yongju Zhao
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 447–457.
https://doi.org/10.1042/BST20211031
Published: 23 December 2021
View articletitled, Current understanding of the role of microRNAs from adipose-derived extracellular vesicles in obesity
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Articles

Alpha-to-beta cell trans-differentiation for treatment of diabetes

Open Access
Mohamed Saleh, George K. Gittes, Krishna Prasadan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2539–2548.
https://doi.org/10.1042/BST20210244
Published: 09 December 2021
View articletitled, Alpha-to-beta cell trans-differentiation for treatment of diabetes
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Includes: Supplementary data
Articles

The role of long non-coding RNAs in the regulation of pancreatic beta cell identity

Open Access
Maya E. Wilson, Timothy J. Pullen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2153–2161.
https://doi.org/10.1042/BST20210207
Published: 28 September 2021
View articletitled, The role of long non-coding RNAs in the regulation of pancreatic beta cell identity
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Articles

Musculoskeletal complications associated with pathological iron toxicity and its molecular mechanisms

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Márcio Simão, M. Leonor Cancela
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 747–759.
https://doi.org/10.1042/BST20200672
Published: 30 April 2021
View articletitled, Musculoskeletal complications associated with pathological iron toxicity and its molecular mechanisms
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Articles

Roles of interstitial fluid pH and weak organic acids in development and amelioration of insulin resistance

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Yoshinori Marunaka
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 715–726.
https://doi.org/10.1042/BST20200667
Published: 26 March 2021
View articletitled, Roles of interstitial fluid pH and weak organic acids in development and amelioration of insulin resistance
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Articles

Molecular mechanisms of transcription factor mediated cell reprogramming: conversion of liver to pancreas

Open Access
Sebastian L. Wild, David Tosh
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 579–590.
https://doi.org/10.1042/BST20200219
Published: 05 March 2021
View articletitled, Molecular mechanisms of transcription factor mediated cell reprogramming: conversion of liver to pancreas
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Articles

Type-2 diabetes, a co-morbidity in Covid-19: does insulin signaling matter?

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In Collection
Coronavirus
Devanshi Mishra, Chinmoy Sankar Dey
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 987–995.
https://doi.org/10.1042/BST20201062
Published: 05 March 2021
View articletitled, Type-2 diabetes, a co-morbidity in Covid-19: does insulin signaling matter?
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Articles

Trans-endothelial trafficking of metabolic substrates and its importance in cardio-metabolic disease

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Ashton Faulkner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 507–517.
https://doi.org/10.1042/BST20200991
Published: 22 February 2021
View articletitled, Trans-endothelial trafficking of metabolic substrates and its importance in cardio-metabolic disease
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Articles

DNA copy number and structural variation (CNV) contributions to adult and childhood obesity

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Megan Phillips, Jeganathan Ramesh Babu, Xu Wang, Thangiah Geetha
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (4): 1819–1828.
https://doi.org/10.1042/BST20200556
Published: 29 July 2020
View articletitled, DNA copy number and structural variation (CNV) contributions to adult and childhood obesity
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Articles

Class IA PI3K regulatory subunits: p110-independent roles and structures

Open Access
Millie Fox, Helen R. Mott, Darerca Owen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (4): 1397–1417.
https://doi.org/10.1042/BST20190845
Published: 17 July 2020
View articletitled, Class IA PI3K regulatory subunits: p110-independent roles and structures
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Articles

Innate immune receptors in type 1 diabetes: the relationship to cell death-associated inflammation

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In Collection
Celebrating 100 years of insulin research
Tae Kang Kim, Myung-Shik Lee
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1213–1225.
https://doi.org/10.1042/BST20200131
Published: 08 June 2020
View articletitled, Innate immune receptors in type 1 diabetes: the relationship to cell death-associated inflammation
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Articles

Gut microbiota and metabolites in the pathogenesis of endocrine disease

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Aline C. Fenneman, Elena Rampanelli, Yue S. Yin, Jesse Ames, Martin J. Blaser, Eric Fliers, Max Nieuwdorp
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 915–931.
https://doi.org/10.1042/BST20190686
Published: 15 May 2020
View articletitled, Gut microbiota and metabolites in the pathogenesis of endocrine disease
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Articles

Lessons from cavin-1 deficiency

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Libin Liu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (1): 147–154.
https://doi.org/10.1042/BST20190380
Published: 10 January 2020
View articletitled, Lessons from cavin-1 deficiency
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Articles

The furanosidic scaffold of d-ribose: a milestone for cell life

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Antonella Del-Corso, Mario Cappiello, Roberta Moschini, Francesco Balestri, Umberto Mura, Piero Luigi Ipata
Journal: Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (6): 1931–1940.
https://doi.org/10.1042/BST20190749
Published: 07 November 2019
View articletitled, The furanosidic scaffold of d-ribose: a milestone for cell life
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Articles

Chloride transporters and channels in β-cell physiology: revisiting a 40-year-old model

Open Access
Mauricio Di Fulvio, Lydia Aguilar-Bryan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (6): 1843–1855.
https://doi.org/10.1042/BST20190513
Published: 07 November 2019
View articletitled, Chloride transporters and channels in β-cell physiology: revisiting a 40-year-old model
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Articles

Is there a causal link between intracellular Na elevation and metabolic remodelling in cardiac hypertrophy?

Open Access
Dunja Aksentijevic, Brett A. O'Brien, Thomas R. Eykyn, Michael J. Shattock
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (4): 817–827.
https://doi.org/10.1042/BST20170508
Published: 03 July 2018
View articletitled, Is there a causal link between intracellular Na elevation and metabolic remodelling in cardiac hypertrophy?
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Articles

Regulation of RabGAPs involved in insulin action

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In Collection
Celebrating 100 years of insulin research
Samaneh Mafakheri, Alexandra Chadt, Hadi Al-Hasani
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (3): 683–690.
https://doi.org/10.1042/BST20170479
Published: 21 May 2018
View articletitled, Regulation of RabGAPs involved in insulin action
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Articles

Control of pancreatic β-cell bioenergetics

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Charles Affourtit, Ben Alberts, Jonathan Barlow, Jane E. Carré, Anthony G. Wynne
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (3): 555–564.
https://doi.org/10.1042/BST20170505
Published: 17 April 2018
View articletitled, Control of pancreatic β-cell bioenergetics
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Articles

Metabolic and molecular changes associated with the increased skeletal muscle insulin action 24–48 h after exercise in young and old humans

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Francis B. Stephens, Kostas Tsintzas
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (1): 111–118.
https://doi.org/10.1042/BST20170198
Published: 12 January 2018
View articletitled, Metabolic and molecular changes associated with the increased skeletal muscle insulin action 24–48 h after exercise in young and old humans
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Articles

Platelet mitochondrial dysfunction and the correlation with human diseases

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Li Wang, Qiang Wu, Zhijia Fan, Rufeng Xie, Zhicheng Wang, Yuan Lu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (6): 1213–1223.
https://doi.org/10.1042/BST20170291
Published: 20 October 2017
View articletitled, Platelet mitochondrial dysfunction and the correlation with human diseases
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Articles

Nutritional modulation of metabolic inflammation

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Anna M. Kirwan, Yvonne M. Lenighan, Marcella E. O'Reilly, Fiona C. McGillicuddy, Helen M. Roche
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (4): 979–985.
https://doi.org/10.1042/BST20160465
Published: 14 July 2017
View articletitled, Nutritional modulation of metabolic inflammation
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Articles

The sweet tooth of the circadian clock

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Minnie Fu, Xiaoyong Yang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (4): 871–884.
https://doi.org/10.1042/BST20160183
Published: 03 July 2017
View articletitled, The sweet tooth of the circadian clock
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Articles

O-GlcNAcylation and cardiovascular disease

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JaLessa N. Wright, Helen E. Collins, Adam R. Wende, John C. Chatham
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (2): 545–553.
https://doi.org/10.1042/BST20160164
Published: 13 April 2017
View articletitled, O-GlcNAcylation and cardiovascular disease
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Articles

Translational control by mTOR-independent routes: how eIF6 organizes metabolism

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Annarita Miluzio, Sara Ricciardi, Nicola Manfrini, Roberta Alfieri, Stefania Oliveto, Daniela Brina, Stefano Biffo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (6): 1667–1673.
https://doi.org/10.1042/BST20160179
Published: 02 December 2016
View articletitled, Translational control by mTOR-independent routes: how eIF6 organizes metabolism
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Articles

The quantum mitochondrion and optimal health

Open Access
Alistair V.W. Nunn, Geoffrey W. Guy, Jimmy D. Bell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (4): 1101–1110.
https://doi.org/10.1042/BST20160096
Published: 15 August 2016
View articletitled, The quantum mitochondrion and optimal health
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