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Articles

Insights into non-proteinaceous ubiquitination

Open Access
Emily L. Dearlove, Danny T. Huang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (02): 399–407.
https://doi.org/10.1042/BST20253029
Published: 03 April 2025
View articletitled, Insights into non-proteinaceous ubiquitination
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Articles

Spo11: from topoisomerase VI to meiotic recombination initiator

Open Access
Jon A. Harper, George G. B. Brown, Matthew J. Neale
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (02): 383–398.
https://doi.org/10.1042/BST20253019
Published: 02 April 2025
View articletitled, Spo11: from topoisomerase VI to meiotic recombination initiator
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Articles

Lysine acetylation in cyanobacteria: emerging mechanisms and functions

Free
Xin Liu, Mingkun Yang, Feng Ge, Jindong Zhao
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 315–326.
https://doi.org/10.1042/BST20241037
Published: 12 February 2025
View articletitled, Lysine acetylation in cyanobacteria: emerging mechanisms and functions
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Articles

Activation is only the beginning: mechanisms that tune kinase substrate specificity

Open Access
Landon K. Clark, Sierra N. Cullati
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 145–159.
https://doi.org/10.1042/BST20241420
Published: 05 February 2025
View articletitled, Activation is only the beginning: mechanisms that tune kinase substrate specificity
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Articles

Insights into mechanisms of ubiquitin ADP-ribosylation reversal

Open Access
Zhengrui Zhang, Chittaranjan Das
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2525–2537.
https://doi.org/10.1042/BST20240896
Published: 25 November 2024
View articletitled, Insights into mechanisms of ubiquitin ADP-ribosylation reversal
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Articles

Beyond expectations: the development and biological activity of cytokinin oxidase/dehydrogenase inhibitors

Available to Purchase
Jaroslav Nisler
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2297–2306.
https://doi.org/10.1042/BST20231561
Published: 07 November 2024
View articletitled, Beyond expectations: the development and biological activity of cytokinin oxidase/dehydrogenase inhibitors
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Articles

The role of prokaryotic argonautes in resistance to type II topoisomerases poison ciprofloxacin

Open Access
Alina Galivondzhyan, Dmitry Sutormin, Vladimir Panteleev, Andrey Kulbachinskiy, Konstantin Severinov
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2157–2166.
https://doi.org/10.1042/BST20240094
Published: 24 October 2024
View articletitled, The role of prokaryotic argonautes in resistance to type II topoisomerases poison ciprofloxacin
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Includes: Supplementary data
Articles

The initiation of mitochondrial DNA replication

Open Access
Yi Liu, Haibin Liu, Fan Zhang, Hong Xu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1243–1251.
https://doi.org/10.1042/BST20230952
Published: 17 June 2024
View articletitled, The initiation of mitochondrial DNA replication
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Articles

Proofreading mechanisms of the innate immune receptor RIG-I: distinguishing self and viral RNA

Open Access
Mihai Solotchi, Smita S. Patel
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1131–1148.
https://doi.org/10.1042/BST20230724
Published: 17 June 2024
View articletitled, Proofreading mechanisms of the innate immune receptor RIG-I: distinguishing self and viral RNA
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Articles

Covalent activity-based probes for imaging of serine proteases

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Marcin Skorenski, Shanping Ji, Steven H. L. Verhelst
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 923–935.
https://doi.org/10.1042/BST20231450
Published: 17 April 2024
View articletitled, Covalent activity-based probes for imaging of serine proteases
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Articles

The ring rules the chain — inositol pyrophosphates and the regulation of inorganic polyphosphate

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Azmi Khan, Manisha Mallick, Jayashree S. Ladke, Rashna Bhandari
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 567–580.
https://doi.org/10.1042/BST20230256
Published: 17 April 2024
View articletitled, The ring rules the chain — inositol pyrophosphates and the regulation of inorganic polyphosphate
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Articles

Friend or foe? Reciprocal regulation between E3 ubiquitin ligases and deubiquitinases

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Derek L. Bolhuis, Michael J. Emanuele, Nicholas G. Brown
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 241–267.
https://doi.org/10.1042/BST20230454
Published: 28 February 2024
View articletitled, Friend or foe? Reciprocal regulation between E3 ubiquitin ligases and deubiquitinases
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Articles

Regulation of cardiomyocyte intracellular trafficking and signal transduction by protein palmitoylation

Open Access
Kobina Essandoh, James P. Teuber, Matthew J. Brody
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 41–53.
https://doi.org/10.1042/BST20221296
Published: 22 February 2024
View articletitled, Regulation of cardiomyocyte intracellular trafficking and signal transduction by protein palmitoylation
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Articles

DDX41: exploring the roles of a versatile helicase

Open Access
Lacey Winstone, Yohan Jung, Yuliang Wu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 395–405.
https://doi.org/10.1042/BST20230725
Published: 13 February 2024
View articletitled, DDX41: exploring the roles of a versatile helicase
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Articles

Adapting enzymes to improve their functionality in plants: why and how

Open Access
Edmar R. Oliveira-Filho, Cătălin Voiniciuc, Andrew D. Hanson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1957–1966.
https://doi.org/10.1042/BST20230532
Published: 03 October 2023
View articletitled, Adapting enzymes to improve their functionality in plants: why and how
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Articles

Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion

Open Access
Chris Greening, Ashleigh Kropp, Kylie Vincent, Rhys Grinter
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1921–1933.
https://doi.org/10.1042/BST20230120
Published: 25 September 2023
View articletitled, Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion
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Articles

Chemical catalysis by biological amyloids

Open Access
Pernilla Wittung-Stafshede
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1967–1974.
https://doi.org/10.1042/BST20230617
Published: 25 September 2023
View articletitled, Chemical catalysis by biological amyloids
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Articles

Insights into the function of cytoglobin

Open Access
Brandon J. Reeder
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1907–1919.
https://doi.org/10.1042/BST20230081
Published: 18 September 2023
View articletitled, Insights into the function of cytoglobin
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Articles

Negative regulation of biofilm formation by nitric oxide sensing proteins

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Sweta Anantharaman, Danielle Guercio, Alicia G. Mendoza, Jason M. Withorn, Elizabeth M. Boon
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1447–1458.
https://doi.org/10.1042/BST20220845
Published: 23 August 2023
View articletitled, Negative regulation of biofilm formation by nitric oxide sensing proteins
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Articles

Biochemical Society Transactions : celebrating 50 years

Open Access
James M. Murphy
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1417–1418.
https://doi.org/10.1042/BST20230828
Published: 23 August 2023
View articletitled, Biochemical Society Transactions : celebrating 50 years
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Articles

New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures

Open Access
Matthieu P.M.H. Benoit, Byron Hunter, John S. Allingham, Hernando Sosa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1505–1520.
https://doi.org/10.1042/BST20221238
Published: 10 August 2023
View articletitled, New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures
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Includes: Supplementary data
Articles

Unlocking the secrets of ABEs: the molecular mechanism behind their specificity

Open Access
Xiaoyu Chen, Mitchell J. McAndrew, Audrone Lapinaite
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1635–1646.
https://doi.org/10.1042/BST20221508
Published: 01 August 2023
View articletitled, Unlocking the secrets of ABEs: the molecular mechanism behind their specificity
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Articles

γ-Secretase fanning the fire of innate immunity

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Chenge Liu, Cyrus Nikain, Yue-Ming Li
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1597–1610.
https://doi.org/10.1042/BST20221445
Published: 14 July 2023
View articletitled, γ-Secretase fanning the fire of innate immunity
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Articles

Biomimetic engineering of nonribosomal peptide synthesis

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Kexin Zhang, Hajo Kries
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1521–1532.
https://doi.org/10.1042/BST20221264
Published: 06 July 2023
View articletitled, Biomimetic engineering of nonribosomal peptide synthesis
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Articles

Mapping lipid pathways during phagocytosis

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Ojal Saharan, Siddhesh S. Kamat
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1279–1287.
https://doi.org/10.1042/BST20221424
Published: 14 June 2023
View articletitled, Mapping lipid pathways during phagocytosis
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Articles

Cytoophidia and filaments: you must unlearn what you have learned

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Chen-Jun Guo, Ji-Long Liu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1245–1256.
https://doi.org/10.1042/BST20221410
Published: 30 May 2023
View articletitled, Cytoophidia and filaments: you must unlearn what you have learned
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Articles

The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation

Open Access
Shang Liang, Rajaei Almohammed, Victoria H. Cowling
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1131–1141.
https://doi.org/10.1042/BST20221154
Published: 05 May 2023
View articletitled, The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation
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Includes: Supplementary data
Articles

The molecular mechanisms of human separase regulation

Open Access
Jun Yu, David O. Morgan, Andreas Boland
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1225–1233.
https://doi.org/10.1042/BST20221400
Published: 04 May 2023
View articletitled, The molecular mechanisms of human separase regulation
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Articles

The functional importance of bacterial oxidative phosphonate pathways

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Katharina Pallitsch, David L. Zechel
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 487–499.
https://doi.org/10.1042/BST20220479
Published: 09 March 2023
View articletitled, The functional importance of bacterial oxidative phosphonate pathways
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Articles

Deciphering the mechanism and function of Hsp100 unfoldases from protein structure

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Grace Lee, Rebecca S. Kim, Sang Bum Lee, Sukyeong Lee, Francis T.F. Tsai
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1725–1736.
https://doi.org/10.1042/BST20220590
Published: 01 December 2022
View articletitled, Deciphering the mechanism and function of Hsp100 unfoldases from protein structure
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Articles

General strategies for using amino acid sequence data to guide biochemical investigation of protein function

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Emily N. Kennedy, Clay A. Foster, Sarah A. Barr, Robert B. Bourret
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1847–1858.
https://doi.org/10.1042/BST20220849
Published: 23 November 2022
View articletitled, General strategies for using amino acid sequence data to guide biochemical investigation of protein function
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Articles

The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI

Open Access
Dmitry Lyumkis, Nancy C. Horton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1703–1714.
https://doi.org/10.1042/BST20220547
Published: 18 November 2022
View articletitled, The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI
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Articles

The functional importance of VCP to maintaining cellular protein homeostasis

Open Access
Brittany A. Ahlstedt, Rakesh Ganji, Malavika Raman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1457–1469.
https://doi.org/10.1042/BST20220648
Published: 05 October 2022
View articletitled, The functional importance of VCP to maintaining cellular protein homeostasis
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Articles

Unveiling the mechanisms and biosynthesis of a novel nickel-pincer enzyme

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Shramana Chatterjee, Santhosh Gatreddi, Swati Gupta, Jorge L. Nevarez, Joel A. Rankin, Aiko Turmo, Jian Hu, Robert P. Hausinger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1187–1196.
https://doi.org/10.1042/BST20220490
Published: 12 August 2022
View articletitled, Unveiling the mechanisms and biosynthesis of a novel nickel-pincer enzyme
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Articles

New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

Open Access
In Collection
Awards
Valerie B. O'Donnell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 1–11.
https://doi.org/10.1042/BST20210579
Published: 28 February 2022
View articletitled, New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease
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Articles

IMPDH dysregulation in disease: a mini review

Open Access
Anika L. Burrell, Justin M. Kollman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 71–82.
https://doi.org/10.1042/BST20210446
Published: 22 February 2022
View articletitled, IMPDH dysregulation in disease: a mini review
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Articles

The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

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Daria Sicari, Janine Weber, Elena Maspero, Simona Polo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 473–485.
https://doi.org/10.1042/BST20210731
Published: 07 February 2022
View articletitled, The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation
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Articles

Improving photosynthesis through the enhancement of Rubisco carboxylation capacity

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Concepción Iñiguez, Pere Aguiló-Nicolau, Jeroni Galmés
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2007–2019.
https://doi.org/10.1042/BST20201056
Published: 08 October 2021
View articletitled, Improving photosynthesis through the enhancement of Rubisco carboxylation capacity
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Articles

The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases

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Katherine H. O'Toole, Hannah M. Bernstein, Karen N. Allen, Barbara Imperiali
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1189–1203.
https://doi.org/10.1042/BST20200762
Published: 08 June 2021
View articletitled, The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases
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Articles

Great balls of fire: activation and signalling of inflammatory caspases

Open Access
Georgia Bateman, Benjamin Hill, Ryan Knight, Dave Boucher
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1311–1324.
https://doi.org/10.1042/BST20200986
Published: 01 June 2021
View articletitled, Great balls of fire: activation and signalling of inflammatory caspases
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Articles

Serpins in cartilage and osteoarthritis: what do we know?

Open Access
David J. Wilkinson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 1013–1026.
https://doi.org/10.1042/BST20201231
Published: 12 April 2021
View articletitled, Serpins in cartilage and osteoarthritis: what do we know?
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Articles

Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes

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Francesca De Giorgi, Marco Fumagalli, Luigi Scietti, Federico Forneris
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 855–866.
https://doi.org/10.1042/BST20200767
Published: 11 March 2021
View articletitled, Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes
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Articles

Plant asparaginyl endopeptidases and their structural determinants of function

Open Access
Samuel G. Nonis, Joel Haywood, Joshua S. Mylne
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 965–976.
https://doi.org/10.1042/BST20200908
Published: 05 March 2021
View articletitled, Plant asparaginyl endopeptidases and their structural determinants of function
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Articles

Structure and evolution of the bifidobacterial carbohydrate metabolism proteins and enzymes

Open Access
Shinya Fushinobu, Maher Abou Hachem
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 563–578.
https://doi.org/10.1042/BST20200163
Published: 05 March 2021
View articletitled, Structure and evolution of the bifidobacterial carbohydrate metabolism proteins and enzymes
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Articles

Computational investigations of allostery in aromatic amino acid biosynthetic enzymes

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Wanting Jiao
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 415–429.
https://doi.org/10.1042/BST20200741
Published: 05 February 2021
View articletitled, Computational investigations of allostery in aromatic amino acid biosynthetic enzymes
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Articles

Lytic polysaccharide monooxygenases and other histidine-brace copper proteins: structure, oxygen activation and biotechnological applications

Open Access
Johan Ø. Ipsen, Magnus Hallas-Møller, Søren Brander, Leila Lo Leggio, Katja S. Johansen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 531–540.
https://doi.org/10.1042/BST20201031
Published: 15 January 2021
View articletitled, Lytic polysaccharide monooxygenases and other histidine-brace copper proteins: structure, oxygen activation and biotechnological applications
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Articles

Solid-state NMR approaches to investigate large enzymes in complex with substrates and inhibitors

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Anne K. Schütz
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 131–144.
https://doi.org/10.1042/BST20200099
Published: 24 December 2020
View articletitled, Solid-state NMR approaches to investigate large enzymes in complex with substrates and inhibitors
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Articles

Anatomy of a twin DNA replication factory

Open Access
Huilin Li, Nina Y. Yao, Michael E. O'Donnell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2769–2778.
https://doi.org/10.1042/BST20200640
Published: 10 December 2020
View articletitled, Anatomy of a twin DNA replication factory
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Articles

‘PIPs’ in DNA polymerase: PCNA interaction affairs

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Narottam Acharya, Shraddheya Kumar Patel, Satya Ranjan Sahu, Premlata Kumari
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2811–2822.
https://doi.org/10.1042/BST20200678
Published: 16 November 2020
View articletitled, ‘PIPs’ in DNA polymerase: PCNA interaction affairs
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Articles

Protein phosphatase-1: dual activity regulation by Inhibitor-2

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Sarah Lemaire, Mathieu Bollen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2229–2240.
https://doi.org/10.1042/BST20200503
Published: 14 October 2020
View articletitled, Protein phosphatase-1: dual activity regulation by Inhibitor-2
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