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Articles

The role of transcription bodies in gene expression: what embryos teach us

Martino Ugolini, Nadine L. Vastenhouw
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 205–213.
https://doi.org/10.1042/BST20240599
Published: 06 February 2025
View articletitled, The role of transcription bodies in gene expression: what embryos teach us
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Articles

Exploring the oncogenic roles of T-box transcription factor TBX2 and its potential as a therapeutic target

Claire Bellis, Mihlali V. Mlaza, Abid Ali, Amaal Abrahams, Sharon Prince
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 193–204.
https://doi.org/10.1042/BST20241069
Published: 06 February 2025
View articletitled, Exploring the oncogenic roles of T-box transcription factor TBX2 and its potential as a therapeutic target
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Articles

Current understanding of heparanase 2 regulation, a non-heparanase

Yannic Becker, Hermann Haller
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 172–179.
https://doi.org/10.1042/BST20241281
Published: 05 February 2025
View articletitled, Current understanding of heparanase 2 regulation, a non-heparanase
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Articles

Microscopy methods for the in vivo study of nanoscale nuclear organization

Nidhi Rani Lokesh, Mark E. Pownall
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 121–133.
https://doi.org/10.1042/BST20240629
Published: 03 February 2025
View articletitled, Microscopy methods for the in vivo study of nanoscale nuclear organization
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Articles

Advances towards potential cancer therapeutics targeting Hippo signaling

Rui Zhu, Zhihan Jiao, Fa-Xing Yu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2399–2413.
https://doi.org/10.1042/BST20240244
Published: 06 December 2024
View articletitled, Advances towards potential cancer therapeutics targeting Hippo signaling
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Articles

Insights into the regulation of mRNA translation by scaffolding proteins

Madeleine R. Smith, Guilherme Costa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2569–2578.
https://doi.org/10.1042/BST20241021
Published: 06 December 2024
View articletitled, Insights into the regulation of mRNA translation by scaffolding proteins
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Articles

Exploring the dynamics of messenger ribonucleoprotein-mediated translation repression

Julia Meyer, Marco Payr, Olivier Duss, Janosch Hennig
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2267–2279.
https://doi.org/10.1042/BST20231240
Published: 27 November 2024
View articletitled, Exploring the dynamics of messenger ribonucleoprotein-mediated translation repression
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Articles

A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway

Tekle Pauzaite, James A. Nathan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2253–2265.
https://doi.org/10.1042/BST20230861
Published: 25 November 2024
View articletitled, A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway
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Articles

Untangling bacterial DNA topoisomerases functions

Céline Borde, Lisa Bruno, Olivier Espéli
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2321–2331.
https://doi.org/10.1042/BST20240089
Published: 07 November 2024
View articletitled, Untangling bacterial DNA topoisomerases functions
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Articles

Using human disease mutations to understand de novo DNA methyltransferase function

Willow Rolls, Marcus D. Wilson, Duncan Sproul
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2059–2075.
https://doi.org/10.1042/BST20231017
Published: 24 October 2024
View articletitled, Using human disease mutations to understand de novo DNA methyltransferase function
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Articles

Understanding the role of ten-eleven translocation family proteins in kidney diseases

Yuelin Zhang, Jiahui Li, Li Tan, Jun Xue, Yujiang Geno Shi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2203–2214.
https://doi.org/10.1042/BST20240291
Published: 08 October 2024
View articletitled, Understanding the role of ten-eleven translocation family proteins in kidney diseases
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Articles

Mechanisms conferring bacterial cell wall variability and adaptivity

Gabriel Torrens, Felipe Cava
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 1981–1993.
https://doi.org/10.1042/BST20230027
Published: 26 September 2024
View articletitled, Mechanisms conferring bacterial cell wall variability and adaptivity
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Articles

Histone H3 mutations and their impact on genome stability maintenance

Lucas D. Caeiro, Ramiro E. Verdun, Lluis Morey
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2179–2191.
https://doi.org/10.1042/BST20240177
Published: 09 September 2024
View articletitled, Histone H3 mutations and their impact on genome stability maintenance
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Articles

How does CHD4 slide nucleosomes?

In Collection
Epigenetics
Xavier J. Reid, Yichen Zhong, Joel P. Mackay
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 1995–2008.
https://doi.org/10.1042/BST20230070
Published: 02 September 2024
View articletitled, How does CHD4 slide nucleosomes?
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Articles

Transcriptional bursting: from fundamentals to novel insights

Daniel Hebenstreit, Pradip Karmakar
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1695–1702.
https://doi.org/10.1042/BST20231286
Published: 09 August 2024
View articletitled, Transcriptional bursting: from fundamentals to novel insights
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Articles

Nuclear RNA: a transcription-dependent regulator of chromatin structure

Jon Stocks, Nick Gilbert
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1605–1615.
https://doi.org/10.1042/BST20230787
Published: 31 July 2024
View articletitled, Nuclear RNA: a transcription-dependent regulator of chromatin structure
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Articles

Cytokinin and reproductive shoot architecture: bigger and better?

Catriona H. Walker, Tom Bennett
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1885–1893.
https://doi.org/10.1042/BST20231565
Published: 31 July 2024
View articletitled, Cytokinin and reproductive shoot architecture: bigger and better?
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Articles

Progress in multifactorial single-cell chromatin profiling methods

In Collection
Epigenetics
Tim Stuart
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1827–1839.
https://doi.org/10.1042/BST20231471
Published: 18 July 2024
View articletitled, Progress in multifactorial single-cell chromatin profiling methods
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Articles

Androgen receptor post-translational modifications and their implications for pathology

Inés Montoya-Novoa, José Luis Gardeazábal-Torbado, Andrea Alegre-Martí, Pablo Fuentes-Prior, Eva Estébanez-Perpiñá
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1673–1694.
https://doi.org/10.1042/BST20231082
Published: 03 July 2024
View articletitled, Androgen receptor post-translational modifications and their implications for pathology
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Articles

TDP-43 in nuclear condensates: where, how, and why

Ruaridh Lang, Rachel E. Hodgson, Tatyana A. Shelkovnikova
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1809–1825.
https://doi.org/10.1042/BST20231447
Published: 03 July 2024
View articletitled, TDP-43 in nuclear condensates: where, how, and why
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Articles

The initiation of mitochondrial DNA replication

Yi Liu, Haibin Liu, Fan Zhang, Hong Xu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1243–1251.
https://doi.org/10.1042/BST20230952
Published: 17 June 2024
View articletitled, The initiation of mitochondrial DNA replication
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Articles

Nucleosomal asymmetry: a novel mechanism to regulate nucleosome function

In Collection
Epigenetics
Devisree Valsakumar, Philipp Voigt
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1219–1232.
https://doi.org/10.1042/BST20230877
Published: 23 May 2024
View articletitled, Nucleosomal asymmetry: a novel mechanism to regulate nucleosome function
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Articles

Exploring the role non-coding RNAs during myocardial cell fate

Diego Franco, Cristina Sánchez-Fernández, Carlos García-Padilla, Estefania Lozano-Velasco
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1339–1348.
https://doi.org/10.1042/BST20231216
Published: 22 May 2024
View articletitled, Exploring the role non-coding RNAs during myocardial cell fate
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Articles

Differential 3D genome architecture and imprinted gene expression: cause or consequence?

Benoit Moindrot, Yui Imaizumi, Robert Feil
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 973–986.
https://doi.org/10.1042/BST20230143
Published: 22 May 2024
View articletitled, Differential 3D genome architecture and imprinted gene expression: cause or consequence?
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Articles

How does the Xist activator Rlim/Rnf12 regulate Xist expression?

Feng Wang, Poonam Mehta, Ingolf Bach
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1099–1107.
https://doi.org/10.1042/BST20230573
Published: 15 May 2024
View articletitled, How does the Xist activator Rlim/Rnf12 regulate Xist expression?
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Articles

Retrotransposons in embryogenesis and neurodevelopment

Mary Jo Talley, Michelle S. Longworth
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1159–1171.
https://doi.org/10.1042/BST20230757
Published: 08 May 2024
View articletitled, Retrotransposons in embryogenesis and neurodevelopment
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Articles

The choreography of chromatin in RNA polymerase III regulation

Maria Elize van Breugel, Alan Gerber, Fred van Leeuwen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1173–1189.
https://doi.org/10.1042/BST20230770
Published: 26 April 2024
View articletitled, The choreography of chromatin in RNA polymerase III regulation
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Articles

The SWI/SNF chromatin remodeling complex: a critical regulator of metabolism

Michael C. Church, Jerry L. Workman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1327–1337.
https://doi.org/10.1042/BST20231141
Published: 26 April 2024
View articletitled, The SWI/SNF chromatin remodeling complex: a critical regulator of metabolism
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Articles

RNA m 6 A modification, signals for degradation or stabilisation?

Guifeng Wei
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 707–717.
https://doi.org/10.1042/BST20230574
Published: 17 April 2024
View articletitled, RNA m 6 A modification, signals for degradation or stabilisation?
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Articles

The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development

Dhurjhoti Saha, Srinivas Animireddy, Blaine Bartholomew
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 603–616.
https://doi.org/10.1042/BST20230416
Published: 04 April 2024
View articletitled, The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development
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Articles

Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models

Eunho Song, Sun Han, Sungchul Hohng, Changwon Kang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 887–897.
https://doi.org/10.1042/BST20231229
Published: 27 March 2024
View articletitled, Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models
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Articles

The molecular mechanisms underpinning maternal mRNA dormancy

Laura Lorenzo-Orts, Andrea Pauli
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 861–871.
https://doi.org/10.1042/BST20231122
Published: 13 March 2024
View articletitled, The molecular mechanisms underpinning maternal mRNA dormancy
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Articles

Beyond protein synthesis: non-translational functions of threonyl-tRNA synthetases

Pallob Barai, Jie Chen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 661–670.
https://doi.org/10.1042/BST20230506
Published: 13 March 2024
View articletitled, Beyond protein synthesis: non-translational functions of threonyl-tRNA synthetases
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Articles

Transcriptional control of neural stem cell activity

Takashi Kaise, Ryoichiro Kageyama
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 617–626.
https://doi.org/10.1042/BST20230439
Published: 13 March 2024
View articletitled, Transcriptional control of neural stem cell activity
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Articles

Genome organization across scales: mechanistic insights from in vitro reconstitution studies

In Collection
Epigenetics
Elisa Oberbeckmann, A. Marieke Oudelaar
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 793–802.
https://doi.org/10.1042/BST20230883
Published: 07 March 2024
View articletitled, Genome organization across scales: mechanistic insights from in vitro reconstitution studies
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Articles

The malarial blood transcriptome: translational applications

Claire Dunican, Clare Andradi-Brown, Stefan Ebmeier, Athina Georgiadou, Aubrey J. Cunnington
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 651–660.
https://doi.org/10.1042/BST20230497
Published: 29 February 2024
View articletitled, The malarial blood transcriptome: translational applications
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Articles

The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies

Gaurav Sharma, Martina Paganin, Fabio Lauria, Elena Perenthaler, Gabriella Viero
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 465–479.
https://doi.org/10.1042/BST20231116
Published: 23 February 2024
View articletitled, The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies
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Articles

Transcriptional repression across mitosis: mechanisms and functions

A. Contreras, C. Perea-Resa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 455–464.
https://doi.org/10.1042/BST20231071
Published: 19 February 2024
View articletitled, Transcriptional repression across mitosis: mechanisms and functions
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Articles

Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin

In Collection
Epigenetics
Peter B. Becker
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 423–429.
https://doi.org/10.1042/BST20230878
Published: 08 February 2024
View articletitled, Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin
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Articles

Polycomb-mediated histone modifications and gene regulation

In Collection
Epigenetics
Shinsuke Ito, Takashi Umehara, Haruhiko Koseki
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 151–161.
https://doi.org/10.1042/BST20230336
Published: 30 January 2024
View articletitled, Polycomb-mediated histone modifications and gene regulation
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Articles

Neurodevelopmental functions of CHD8: new insights and questions

M. Albert Basson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 15–27.
https://doi.org/10.1042/BST20220926
Published: 30 January 2024
View articletitled, Neurodevelopmental functions of CHD8: new insights and questions
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Articles

Genetic regulation of enteric nervous system development in zebrafish

Rosa A. Uribe
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 177–190.
https://doi.org/10.1042/BST20230343
Published: 04 January 2024
View articletitled, Genetic regulation of enteric nervous system development in zebrafish
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Articles

Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection

In Collection
Coronavirus
Debjit Khan, Paul L. Fox
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (6): 2127–2141.
https://doi.org/10.1042/BST20230527
Published: 18 December 2023
View articletitled, Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection
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Articles

The multifunctional role of intrinsic disorder in NF-κB signaling

Elizabeth A. Komives
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (6): 2085–2092.
https://doi.org/10.1042/BST20230035
Published: 14 December 2023
View articletitled, The multifunctional role of intrinsic disorder in NF-κB signaling
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Articles

Biochemical Society Transactions : celebrating 50 years

James M. Murphy
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1417–1418.
https://doi.org/10.1042/BST20230828
Published: 23 August 2023
View articletitled, Biochemical Society Transactions : celebrating 50 years
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Articles

Functions and mechanisms of the GPCR adaptor protein Norbin

Stephen A. Chetwynd, Simon Andrews, Sarah Inglesfield, Christine Delon, Nicholas T. Ktistakis, Heidi C. E. Welch
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1545–1558.
https://doi.org/10.1042/BST20221349
Published: 28 July 2023
View articletitled, Functions and mechanisms of the GPCR adaptor protein Norbin
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Articles

The central role of translation elongation in response to stress

Géssica C. Barros, Sofia Guerrero, Gustavo M. Silva
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 959–969.
https://doi.org/10.1042/BST20220584
Published: 15 June 2023
View articletitled, The central role of translation elongation in response to stress
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Articles

The discovery, function, and regulation of epithelial splicing regulatory proteins (ESRP) 1 and 2

Jessica M. Derham, Auinash Kalsotra
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1097–1109.
https://doi.org/10.1042/BST20221124
Published: 14 June 2023
View articletitled, The discovery, function, and regulation of epithelial splicing regulatory proteins (ESRP) 1 and 2
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Articles

The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective

Belén Chaves-Arquero, José Manuel Pérez-Cañadillas
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1257–1269.
https://doi.org/10.1042/BST20221418
Published: 24 May 2023
View articletitled, The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective
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Includes: Supplementary data
Articles

Mechanisms of impairment of interferon production by SARS-CoV-2

In Collection
Coronavirus
Huy-Dung Hoang, Parisa Naeli, Tommy Alain, Seyed Mehdi Jafarnejad
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1047–1056.
https://doi.org/10.1042/BST20221037
Published: 18 May 2023
View articletitled, Mechanisms of impairment of interferon production by SARS-CoV-2
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