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Articles

Current understanding of heparanase 2 regulation, a non-heparanase

Yannic Becker, Hermann Haller
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 172–179.
https://doi.org/10.1042/BST20241281
Published: 05 February 2025
View articletitled, Current understanding of heparanase 2 regulation, a non-heparanase
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Articles

Structural glycobiology – from enzymes to organelles

Courtney J. Mycroft-West, Miron A. Leanca, Liang Wu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 83–100.
https://doi.org/10.1042/BST20241119
Published: 31 January 2025
View articletitled, Structural glycobiology – from enzymes to organelles
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Articles

Tools and techniques for quantitative glycoproteomic analysis

Siyuan Kong, Wei Zhang, Weiqian Cao
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2439–2453.
https://doi.org/10.1042/BST20240257
Published: 10 December 2024
View articletitled, Tools and techniques for quantitative glycoproteomic analysis
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Articles

Linking glycosphingolipid metabolism to disease-related changes in the plasma membrane proteome

Holly Monkhouse, Janet E. Deane
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2477–2486.
https://doi.org/10.1042/BST20240315
Published: 06 December 2024
View articletitled, Linking glycosphingolipid metabolism to disease-related changes in the plasma membrane proteome
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Articles

The expanding boundaries of sphingolipid lysosomal storage diseases; insights from Niemann–Pick disease type C

In Collection
Awards
Frances M. Platt
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1777–1787.
https://doi.org/10.1042/BST20220711
Published: 16 October 2023
View articletitled, The expanding boundaries of sphingolipid lysosomal storage diseases; insights from Niemann–Pick disease type C
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Articles

The role of lipid scramblases in regulating lipid distributions at cellular membranes

Yicheng Wang, Taroh Kinoshita
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1857–1869.
https://doi.org/10.1042/BST20221455
Published: 28 September 2023
View articletitled, The role of lipid scramblases in regulating lipid distributions at cellular membranes
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Articles

Mammalian cargo receptors for endoplasmic reticulum-to-Golgi transport: mechanisms and interactions

Yuan Zhang, Vishal Srivastava, Bin Zhang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 971–981.
https://doi.org/10.1042/BST20220713
Published: 19 June 2023
View articletitled, Mammalian cargo receptors for endoplasmic reticulum-to-Golgi transport: mechanisms and interactions
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Articles

The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis

Fabian Gude, Jurij Froese, Georg Steffes, Kay Grobe
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 983–993.
https://doi.org/10.1042/BST20220719
Published: 24 May 2023
View articletitled, The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis
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Articles

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Zhengyuan Huang, Pei F. Lai, Alexander T. H. Cocker, Stuart M. Haslam, Anne Dell, Hugh J. M. Brady, Mark R. Johnson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 639–653.
https://doi.org/10.1042/BST20221406
Published: 16 March 2023
View articletitled, Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology
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Articles

The O -GlcNAc cycling in neurodevelopment and associated diseases

Dawn M. Wenzel, Stephanie Olivier-Van Stichelen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1693–1702.
https://doi.org/10.1042/BST20220539
Published: 16 November 2022
View articletitled, The O -GlcNAc cycling in neurodevelopment and associated diseases
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Articles

Relationship between mucosa-associated gut microbiota and human diseases

Nathalie Juge
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1225–1236.
https://doi.org/10.1042/BST20201201
Published: 10 October 2022
View articletitled, Relationship between mucosa-associated gut microbiota and human diseases
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Articles

Identification, function, and biological relevance of POGLUT2 and POGLUT3

Daniel B. Williamson, Robert S. Haltiwanger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 1003–1012.
https://doi.org/10.1042/BST20210850
Published: 11 April 2022
View articletitled, Identification, function, and biological relevance of POGLUT2 and POGLUT3
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Articles

Glycans that regulate Notch signaling in the intestine

Mohd Nauman, Pamela Stanley
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 689–701.
https://doi.org/10.1042/BST20200782
Published: 21 March 2022
View articletitled, Glycans that regulate Notch signaling in the intestine
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Articles

Writing and erasing O- GlcNAc from target proteins in cells

Yun Ge, Christina M. Woo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2891–2901.
https://doi.org/10.1042/BST20210865
Published: 16 November 2021
View articletitled, Writing and erasing O- GlcNAc from target proteins in cells
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Articles

Semi- and fully synthetic carbohydrate vaccines against pathogenic bacteria: recent developments

Magdalena E. Zasłona, A. Michael Downey, Peter H. Seeberger, Oren Moscovitz
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2411–2429.
https://doi.org/10.1042/BST20210766
Published: 08 September 2021
View articletitled, Semi- and fully synthetic carbohydrate vaccines against pathogenic bacteria: recent developments
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Articles

The Hitchhiker's guide to glycoproteomics

Tiago Oliveira, Morten Thaysen-Andersen, Nicolle H. Packer, Daniel Kolarich
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1643–1662.
https://doi.org/10.1042/BST20200879
Published: 20 July 2021
View articletitled, The Hitchhiker's guide to glycoproteomics
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Articles

The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases

Katherine H. O'Toole, Hannah M. Bernstein, Karen N. Allen, Barbara Imperiali
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1189–1203.
https://doi.org/10.1042/BST20200762
Published: 08 June 2021
View articletitled, The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases
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Articles

Chemical reporters to study mammalian O-glycosylation

Kathryn E. Huxley, Lianne I. Willems
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 903–913.
https://doi.org/10.1042/BST20200839
Published: 16 April 2021
View articletitled, Chemical reporters to study mammalian O-glycosylation
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Articles

Nutrient regulation of the flow of genetic information by O-GlcNAcylation

Yi Zhu, Gerald W. Hart
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 867–880.
https://doi.org/10.1042/BST20200769
Published: 26 March 2021
View articletitled, Nutrient regulation of the flow of genetic information by O-GlcNAcylation
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Articles

Glycoengineering Chinese hamster ovary cells: a short history

Roberto Donini, Stuart M. Haslam, Cleo Kontoravdi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 915–931.
https://doi.org/10.1042/BST20200840
Published: 11 March 2021
View articletitled, Glycoengineering Chinese hamster ovary cells: a short history
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Articles

Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes

Francesca De Giorgi, Marco Fumagalli, Luigi Scietti, Federico Forneris
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 855–866.
https://doi.org/10.1042/BST20200767
Published: 11 March 2021
View articletitled, Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes
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Articles

Aberrant protein glycosylation in cancer: implications in targeted therapy

Joana G. Rodrigues, Henrique O. Duarte, Celso A. Reis, Joana Gomes
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 843–854.
https://doi.org/10.1042/BST20200763
Published: 11 March 2021
View articletitled, Aberrant protein glycosylation in cancer: implications in targeted therapy
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Articles

Keratan sulfate-based glycomimetics using Langerin as a target for COPD: lessons from studies on Fut8 and core fucose

Yuki Ohkawa, Yoichiro Harada, Naoyuki Taniguchi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 441–453.
https://doi.org/10.1042/BST20200780
Published: 22 February 2021
View articletitled, Keratan sulfate-based glycomimetics using Langerin as a target for COPD: lessons from studies on Fut8 and core fucose
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Articles

A mass spectrometry-based glycotope-centric cellular glycomics is the more fruitful way forward to see the forest for the trees

Kay-Hooi Khoo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 55–69.
https://doi.org/10.1042/BST20190861
Published: 25 January 2021
View articletitled, A mass spectrometry-based glycotope-centric cellular glycomics is the more fruitful way forward to see the forest for the trees
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Articles

Towards structure-focused glycoproteomics

Anastasia Chernykh, Rebeca Kawahara, Morten Thaysen-Andersen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 161–186.
https://doi.org/10.1042/BST20200222
Published: 13 January 2021
View articletitled, Towards structure-focused glycoproteomics
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Articles

Galectin-8, cytokines, and the storm

Yehiel Zick
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 135–149.
https://doi.org/10.1042/BST20200677
Published: 11 January 2021
View articletitled, Galectin-8, cytokines, and the storm
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Articles

The role of extracellular matrix in tumour angiogenesis: the throne has NOx servants

Amir M. Alsharabasy, Sharon A. Glynn, Abhay Pandit
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2539–2555.
https://doi.org/10.1042/BST20200208
Published: 05 November 2020
View articletitled, The role of extracellular matrix in tumour angiogenesis: the throne has NOx servants
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Articles

A ‘tad’ of hope in the fight against airway disease

Eamon Dubaissi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2347–2357.
https://doi.org/10.1042/BST20200745
Published: 20 October 2020
View articletitled, A ‘tad’ of hope in the fight against airway disease
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Articles

Leloir glycosyltransferases of natural product C -glycosylation: structure, mechanism and specificity

Gregor Tegl, Bernd Nidetzky
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (4): 1583–1598.
https://doi.org/10.1042/BST20191140
Published: 13 July 2020
View articletitled, Leloir glycosyltransferases of natural product C -glycosylation: structure, mechanism and specificity
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Articles

Full-length galectin-8 and separate carbohydrate recognition domains: the whole is greater than the sum of its parts?

Alejandro J. Cagnoni, María F. Troncoso, Gabriel A. Rabinovich, Karina V. Mariño, María T. Elola
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1255–1268.
https://doi.org/10.1042/BST20200311
Published: 29 June 2020
View articletitled, Full-length galectin-8 and separate carbohydrate recognition domains: the whole is greater than the sum of its parts?
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Includes: Supplementary data
Articles

Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis

Schuyler A. Chambers, Steven D. Townsend
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1139–1151.
https://doi.org/10.1042/BST20191144
Published: 29 June 2020
View articletitled, Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis
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Articles

Mammalian GPI-anchor modifications and the enzymes involved

Yi-Shi Liu, Morihisa Fujita
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1129–1138.
https://doi.org/10.1042/BST20191142
Published: 23 June 2020
View articletitled, Mammalian GPI-anchor modifications and the enzymes involved
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Articles

Promiscuity and specificity of eukaryotic glycosyltransferases

Ansuman Biswas, Mukund Thattai
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 891–900.
https://doi.org/10.1042/BST20190651
Published: 15 June 2020
View articletitled, Promiscuity and specificity of eukaryotic glycosyltransferases
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Articles

α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19

In Collection
Coronavirus
Spencer J. Williams, Ethan D. Goddard-Borger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1287–1295.
https://doi.org/10.1042/BST20200505
Published: 08 June 2020
View articletitled, α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19
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Articles

Biomolecular complex viewed by dynamic nuclear polarization solid-state NMR spectroscopy

Arnab Chakraborty, Fabien Deligey, Jenny Quach, Frederic Mentink-Vigier, Ping Wang, Tuo Wang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1089–1099.
https://doi.org/10.1042/BST20191084
Published: 07 May 2020
View articletitled, Biomolecular complex viewed by dynamic nuclear polarization solid-state NMR spectroscopy
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Articles

Bacterial glycans and their interactions with lectins in the innate immune system

Mariano Prado Acosta, Bernd Lepenies
Journal: Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (6): 1569–1579.
https://doi.org/10.1042/BST20170410
Published: 14 November 2019
View articletitled, Bacterial glycans and their interactions with lectins in the innate immune system
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Articles

Therapeutic strategies to target microbial protein–glycosaminoglycan interactions

Johannes Almer, Bernd Gesslbauer, Andreas J. Kungl
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (6): 1505–1515.
https://doi.org/10.1042/BST20170485
Published: 31 October 2018
View articletitled, Therapeutic strategies to target microbial protein–glycosaminoglycan interactions
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Articles

Recent insights into lytic polysaccharide monooxygenases (LPMOs)

Tobias Tandrup, Kristian E. H. Frandsen, Katja S. Johansen, Jean-Guy Berrin, Leila Lo Leggio
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (6): 1431–1447.
https://doi.org/10.1042/BST20170549
Published: 31 October 2018
View articletitled, Recent insights into lytic polysaccharide monooxygenases (LPMOs)
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Articles

Mucins: the frontline defence of the lung

Caroline Ridley, David J. Thornton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (5): 1099–1106.
https://doi.org/10.1042/BST20170402
Published: 28 August 2018
View articletitled, Mucins: the frontline defence of the lung
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Articles

Marine glycosaminoglycan-like carbohydrates as potential drug candidates for infectious disease

Courtney J. Mycroft-West, Edwin A. Yates, Mark A. Skidmore
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (4): 919–929.
https://doi.org/10.1042/BST20170404
Published: 19 July 2018
View articletitled, Marine glycosaminoglycan-like carbohydrates as potential drug candidates for infectious disease
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Articles

The role of heparan sulfate in host macrophage infection by Leishmania species

Marissa L. Maciej-Hulme, Mark A. Skidmore, Helen P. Price
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (4): 789–796.
https://doi.org/10.1042/BST20170398
Published: 22 June 2018
View articletitled, The role of heparan sulfate in host macrophage infection by Leishmania species
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Articles

O-linked mucin-type glycosylation in breast cancer

Joy M. Burchell, Richard Beatson, Rosalind Graham, Joyce Taylor-Papadimitriou, Virginia Tajadura-Ortega
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (4): 779–788.
https://doi.org/10.1042/BST20170483
Published: 14 June 2018
View articletitled, O-linked mucin-type glycosylation in breast cancer
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Articles

Role of mucins in lung homeostasis: regulated expression and biosynthesis in health and disease

Breanna A. Symmes, Adrianne L. Stefanski, Chelsea M. Magin, Christopher M. Evans
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (3): 707–719.
https://doi.org/10.1042/BST20170455
Published: 25 May 2018
View articletitled, Role of mucins in lung homeostasis: regulated expression and biosynthesis in health and disease
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Articles

Harnessing post-translational modifications for next-generation HIV immunogens

Joel D. Allen, Rogier W. Sanders, Katie J. Doores, Max Crispin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (3): 691–698.
https://doi.org/10.1042/BST20170394
Published: 21 May 2018
View articletitled, Harnessing post-translational modifications for next-generation HIV immunogens
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Articles

Latest developments in MUC1 immunotherapy

Joyce Taylor-Papadimitriou, Joy M. Burchell, Rosalind Graham, Richard Beatson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (3): 659–668.
https://doi.org/10.1042/BST20170400
Published: 21 May 2018
View articletitled, Latest developments in MUC1 immunotherapy
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Articles

Insights into toxic Prymnesium parvum blooms: the role of sugars and algal viruses

Ben A. Wagstaff, Edward S. Hems, Martin Rejzek, Jennifer Pratscher, Elliot Brooks, Sakonwan Kuhaudomlarp, Ellis C. O'Neill, Matthew I. Donaldson, Steven Lane, John Currie, Andrew M. Hindes, Gill Malin, J. Colin Murrell, Robert A. Field
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (2): 413–421.
https://doi.org/10.1042/BST20170393
Published: 14 March 2018
View articletitled, Insights into toxic Prymnesium parvum blooms: the role of sugars and algal viruses
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Articles

Glycobiology of syndecan-1 in bacterial infections

Rafael S. Aquino, Yvonne Hui-Fang Teng, Pyong Woo Park
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (2): 371–377.
https://doi.org/10.1042/BST20170395
Published: 09 March 2018
View articletitled, Glycobiology of syndecan-1 in bacterial infections
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Articles

Glycosylation pathways at the ocular surface

Maria C. Rodriguez Benavente, Pablo Argüeso
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (2): 343–350.
https://doi.org/10.1042/BST20170408
Published: 09 March 2018
View articletitled, Glycosylation pathways at the ocular surface
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Articles

Signaling through plant lectins: modulation of plant immunity and beyond

Sofie Van Holle, Els J.M. Van Damme
Journal: Biochemical Society Transactions
Biochem Soc Trans (2018) 46 (2): 217–233.
https://doi.org/10.1042/BST20170371
Published: 22 February 2018
View articletitled, Signaling through plant lectins: modulation of plant immunity and beyond
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Articles

Design starch: stochastic modeling of starch granule biogenesis

Adélaïde Raguin, Oliver Ebenhöh
Journal: Biochemical Society Transactions
Biochem Soc Trans (2017) 45 (4): 885–893.
https://doi.org/10.1042/BST20160407
Published: 03 July 2017
View articletitled, Design starch: stochastic modeling of starch granule biogenesis
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