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Interactions between amyloid, amyloid precursor protein, and mitochondria

Heather M. Wilkins

Biochem Soc Trans (2023) BST20220518.

DOI: https://doi.org/10.1042/BST20220518

Published: 23 January 2023

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Therapeutic targeting of eukaryotic initiation factor (eIF) 4E

Jerry Pelletier, Nahum Sonenberg

Biochem Soc Trans (2023) BST20220285.

DOI: https://doi.org/10.1042/BST20220285

Published: 20 January 2023

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From seeds to trees: how E2 enzymes grow ubiquitin chains

Adam J. Middleton, Catherine L. Day

Biochem Soc Trans (2023) BST20220880.

DOI: https://doi.org/10.1042/BST20220880

Published: 16 January 2023

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The interactions of amyloid β aggregates with phospholipid membranes and the implications for neurodegeneration

Rima Budvytyte, Gintaras Valincius

Biochem Soc Trans (2023) BST20220434.

DOI: https://doi.org/10.1042/BST20220434

Published: 11 January 2023

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Loss of brain energy metabolism control as a driver for memory impairment upon insulin resistance

João M. N. Duarte

Biochem Soc Trans (2023) BST20220789.

DOI: https://doi.org/10.1042/BST20220789

Published: 06 January 2023

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The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer

Aristeidis Panagiotis Sfakianos, Rebecca Mallory Raven, Anne Elizabeth Willis

Biochem Soc Trans (2022) 50 (6): 1885–1895.

DOI: https://doi.org/10.1042/BST20221035

Published: 13 December 2022

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Is bRaQCing bad? New roles for ribosome associated quality control factors in stress granule regulation

Noah S. Helton, Stephanie L. Moon

Biochem Soc Trans (2022) 50 (6): 1715–1724.

DOI: https://doi.org/10.1042/BST20220549

Published: 09 December 2022

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Exploring craniofacial and dental development with microRNAs

Dan Su, Tadkamol Krongbaramee, Hongli Sun, Liu Hong, Brad A. Amendt

Biochem Soc Trans (2022) 50 (6): 1897–1909.

DOI: https://doi.org/10.1042/BST20221042

Published: 09 December 2022

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The octadecanoids: an emerging class of lipid mediators

Alessandro Quaranta, Johanna Revol-Cavalier, Craig E. Wheelock

Biochem Soc Trans (2022) 50 (6): 1569–1582.

DOI: https://doi.org/10.1042/BST20210644

Published: 01 December 2022

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Investigating how intrinsically disordered regions contribute to protein function using HDX-MS

Matthew A.H. Parson, Meredith L. Jenkins, John E. Burke

Biochem Soc Trans (2022) 50 (6): 1607–1617.

DOI: https://doi.org/10.1042/BST20220206

Published: 01 December 2022

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Activities and binding partners of E3 ubiquitin ligase DTX3L and its roles in cancer

Carlos Vela-Rodríguez, Lari Lehtiö

Biochem Soc Trans (2022) 50 (6): 1683–1692.

DOI: https://doi.org/10.1042/BST20220501

Published: 24 November 2022

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The intracellular signaling pathways governing macrophage activation and function in human atherosclerosis

Heather M. Wilson

Biochem Soc Trans (2022) 50 (6): 1673–1682.

DOI: https://doi.org/10.1042/BST20220441

Published: 23 November 2022

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ISG15 driven cellular responses to virus infection

Deeksha Munnur, Adrianna Banducci-Karp, Sumana Sanyal

Biochem Soc Trans (2022) 50 (6): 1837–1846.

DOI: https://doi.org/10.1042/BST20220839

Published: 23 November 2022

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Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt

Neha Mani, Rie Nygaard, Filippo Mancia

Biochem Soc Trans (2022) 50 (6): 1763–1772.

DOI: https://doi.org/10.1042/BST20220634

Published: 23 November 2022

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Articles

Cardiotoxicity of pyrethroids: molecular mechanisms and therapeutic options for acute and long-term toxicity

Leisiane P. Marques, Julliane V. Joviano-Santos, Diego S. Souza, A. Santos-Miranda, D. Roman-Campos

Biochem Soc Trans (2022) 50 (6): 1737–1751.

DOI: https://doi.org/10.1042/BST20220593

Published: 16 November 2022

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Laminin N-terminus (LaNt) proteins, laminins and basement membrane regulation

Natasha D. Chavda, Bilge Sari, Fawziah M. Asiri, Kevin J. Hamill

Biochem Soc Trans (2022) 50 (6): 1541–1553.

DOI: https://doi.org/10.1042/BST20210240

Published: 10 November 2022

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ERK1/2 in immune signalling

Richard M. Lucas, Lin Luo, Jennifer L. Stow

Biochem Soc Trans (2022) 50 (5): 1341–1352.

DOI: https://doi.org/10.1042/BST20220271

Published: 25 October 2022

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Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT

Theresa M. Smith, Barry M. Willardson

Biochem Soc Trans (2022) 50 (5): 1403–1414.

DOI: https://doi.org/10.1042/BST20220591

Published: 05 October 2022

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Articles

Propagation of Parkinson's disease by extracellular vesicle production and secretion

Laura E. Shippey, Susan G. Campbell, Andrew F. Hill, David P. Smith

Biochem Soc Trans (2022) 50 (5): 1303–1314.

DOI: https://doi.org/10.1042/BST20220204

Published: 16 September 2022

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Articles

Protective HLA-B57: T cell and natural killer cell recognition in HIV infection

Christian A. Lobos, Jonathan Downing, Lloyd J. D'Orsogna, Demetra S.M. Chatzileontiadou, Stephanie Gras

Biochem Soc Trans (2022) 50 (5): 1329–1339.

DOI: https://doi.org/10.1042/BST20220244

Published: 16 September 2022

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Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury

Paul T. Morse, Junmei Wan, Jamie Bell, Icksoo Lee, Dennis J. Goebel, Moh H. Malek, Thomas H. Sanderson, Maik Hüttemann

Biochem Soc Trans (2022) 50 (5): 1377–1388.

DOI: https://doi.org/10.1042/BST20220446

Published: 06 September 2022

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CDKL5 deficiency disorder: molecular insights and mechanisms of pathogenicity to fast-track therapeutic development

Nicole J. Van Bergen, Sean Massey, Anita Quigley, Ben Rollo, Alexander R. Harris, Robert M.I. Kapsa, John Christodoulou

Biochem Soc Trans (2022) 50 (4): 1207–1224.

DOI: https://doi.org/10.1042/BST20220791

Published: 23 August 2022

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GPX4: old lessons, new features

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Cell death and survival

Thamara Nishida Xavier da Silva, José Pedro Friedmann Angeli, Irina Ingold

Biochem Soc Trans (2022) 50 (3): 1205–1213.

DOI: https://doi.org/10.1042/BST20220682

Published: 27 June 2022

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Investigating chromatin accessibility during development and differentiation by ATAC-sequencing to guide the identification of cis -regulatory elements

Emily Louise Smith, Gi Fay Mok, Andrea Münsterberg

Biochem Soc Trans (2022) 50 (3): 1167–1177.

DOI: https://doi.org/10.1042/BST20210834

Published: 23 May 2022

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Emerging roles of lncRNAs in the pathogenesis, diagnosis, and treatment of trigeminal neuralgia

Tianyi Wang, Liu Liu, Dongzhe Song, Dingming Huang

Biochem Soc Trans (2022) 50 (2): 1013–1023.

DOI: https://doi.org/10.1042/BST20220070

Published: 19 April 2022

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Articles

Three-dimensional models of the lung: past, present and future: a mini review

Chandani Sen, Delilah Freund, Brigitte N. Gomperts

Biochem Soc Trans (2022) 50 (2): 1045–1056.

DOI: https://doi.org/10.1042/BST20190569

Published: 11 April 2022

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MicroRNAs in neural crest development and neurocristopathies

Marco Antonaci, Grant N. Wheeler

Biochem Soc Trans (2022) 50 (2): 965–974.

DOI: https://doi.org/10.1042/BST20210828

Published: 06 April 2022

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MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Steven R. Van Doren

Biochem Soc Trans (2022) 50 (2): 839–851.

DOI: https://doi.org/10.1042/BST20210640

Published: 28 March 2022

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Linear ubiquitination in immune and neurodegenerative diseases, and beyond

In Collection

Cell death and survival

Fuminori Tokunaga, Fumiyo Ikeda

Biochem Soc Trans (2022) 50 (2): 799–811.

DOI: https://doi.org/10.1042/BST20211078

Published: 28 March 2022

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Articles

Spatial sequestration of misfolded proteins in neurodegenerative diseases

Sarah Rolli, Emily Mitchell Sontag

Biochem Soc Trans (2022) 50 (2): 759–771.

DOI: https://doi.org/10.1042/BST20210862

Published: 21 March 2022

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Articles

GCN2: roles in tumour development and progression

Lyssa T. Gold, Glenn R. Masson

Biochem Soc Trans (2022) 50 (2): 737–745.

DOI: https://doi.org/10.1042/BST20211252

Published: 21 March 2022

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Articles

Drug repurposing in silico screening platforms

Jonathan G.L. Mullins

Biochem Soc Trans (2022) 50 (2): 747–758.

DOI: https://doi.org/10.1042/BST20200967

Published: 14 March 2022

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Articles

Modeling Parkinson's disease in LRRK2 mice: focus on synaptic dysfunction and the autophagy-lysosomal pathway

Federica Albanese, Chiara Domenicale, Mattia Volta, Michele Morari

Biochem Soc Trans (2022) 50 (1): 621–632.

DOI: https://doi.org/10.1042/BST20211288

Published: 28 February 2022

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Role of macrophage extracellular traps in innate immunity and inflammatory disease

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Cell death and survival

Kristian H. Rasmussen, Clare L. Hawkins

Biochem Soc Trans (2022) 50 (1): 21–32.

DOI: https://doi.org/10.1042/BST20210962

Published: 22 February 2022

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Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

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Cell death and survival

Sarah E. Garnish, Joanne M. Hildebrand

Biochem Soc Trans (2022) 50 (1): 529–539.

DOI: https://doi.org/10.1042/BST20210517

Published: 15 February 2022

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Articles

The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

Daria Sicari, Janine Weber, Elena Maspero, Simona Polo

Biochem Soc Trans (2022) 50 (1): 473–485.

DOI: https://doi.org/10.1042/BST20210731

Published: 07 February 2022

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Articles

Mechanism of action of nucleotide excision repair machinery

Areetha D'Souza, Alexandra M. Blee, Walter J. Chazin

Biochem Soc Trans (2022) 50 (1): 375–386.

DOI: https://doi.org/10.1042/BST20210246

Published: 25 January 2022

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Articles

Three-dimensional insights into human enveloped viruses in vitro and in situ

Naveen Vankadari, Doulin C. Shepherd, Stephen D. Carter, Debnath Ghosal

Biochem Soc Trans (2022) 50 (1): 95–105.

DOI: https://doi.org/10.1042/BST20210433

Published: 25 January 2022

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Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)

Jai Woo Lee, Miguel A. Maria-Solano, Thi Ngoc Lan Vu, Sanghee Yoon, Sun Choi

Biochem Soc Trans (2022) 50 (1): 241–252.

DOI: https://doi.org/10.1042/BST20211240

Published: 25 January 2022

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Identifying new molecular players in extracellular proteostasis

Sandeep Satapathy, Mark R. Wilson

Biochem Soc Trans (2022) 50 (1): 321–334.

DOI: https://doi.org/10.1042/BST20210369

Published: 23 December 2021

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The molecular pathogenesis of repeat expansion diseases

Yuzo Fujino, Yoshitaka Nagai

Biochem Soc Trans (2022) 50 (1): 119–134.

DOI: https://doi.org/10.1042/BST20200143

Published: 23 December 2021

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Current understanding of the role of microRNAs from adipose-derived extracellular vesicles in obesity

Le Zhao, Haili Yang, Xingchun Li, Yongju Zhao

Biochem Soc Trans (2022) 50 (1): 447–457.

DOI: https://doi.org/10.1042/BST20211031

Published: 23 December 2021

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HSP90 as a regulator of extracellular matrix dynamics

Abir Chakraborty, Adrienne Lesley Edkins

Biochem Soc Trans (2021) 49 (6): 2611–2625.

DOI: https://doi.org/10.1042/BST20210374

Published: 16 December 2021

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VDAC2 and the BCL-2 family of proteins

In Collection

Cell death and survival

Zheng Yuan, Grant Dewson, Peter E. Czabotar, Richard W. Birkinshaw

Biochem Soc Trans (2021) 49 (6): 2787–2795.

DOI: https://doi.org/10.1042/BST20210753

Published: 16 December 2021

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PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

In Collection

Cell death and survival

Chloe M. McKee, Fabian A. Fischer, Jelena S. Bezbradica, Rebecca C. Coll

Biochem Soc Trans (2021) 49 (6): 2495–2507.

DOI: https://doi.org/10.1042/BST20200987

Published: 02 December 2021

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The role of chromatin at transcription-replication conflicts as a genome safeguard

Aleix Bayona-Feliu, Andrés Aguilera

Biochem Soc Trans (2021) 49 (6): 2727–2736.

DOI: https://doi.org/10.1042/BST20210691

Published: 25 November 2021

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Insights into neurodegeneration from electron microscopy studies

R. Anthony Crowther

Biochem Soc Trans (2021) 49 (6): 2777–2786.

DOI: https://doi.org/10.1042/BST20210719

Published: 23 November 2021

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The role of protein acetylation in regulating mitochondrial fusion and fission

Golam M. Uddin, Rafa Abbas, Timothy E. Shutt

Biochem Soc Trans (2021) 49 (6): 2807–2819.

DOI: https://doi.org/10.1042/BST20210798

Published: 23 November 2021

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LUBAC: a new player in polyglucosan body disease

Andrew Aboujaoude, Berge Minassian, Sharmistha Mitra

Biochem Soc Trans (2021) 49 (5): 2443–2454.

DOI: https://doi.org/10.1042/BST20210838

Published: 28 October 2021

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Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine

Marina Diotallevi, Faseeha Ayaz, Thomas Nicol, Mark J. Crabtree

Biochem Soc Trans (2021) 49 (5): 2189–2198.

DOI: https://doi.org/10.1042/BST20210269

Published: 19 October 2021

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