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Articles

Same same but different? How blood and lymphatic vessels induce cell contact inhibition

Claudia Carlantoni, Leon M.H. Liekfeld, Manu Beerens, Maike Frye
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 181–191.
https://doi.org/10.1042/BST20240573
Published: 06 February 2025
View articletitled, Same same but different? How blood and lymphatic vessels induce cell contact inhibition
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Articles

Exploring the oncogenic roles of T-box transcription factor TBX2 and its potential as a therapeutic target

Claire Bellis, Mihlali V. Mlaza, Abid Ali, Amaal Abrahams, Sharon Prince
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 193–204.
https://doi.org/10.1042/BST20241069
Published: 06 February 2025
View articletitled, Exploring the oncogenic roles of T-box transcription factor TBX2 and its potential as a therapeutic target
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Articles

Structural switching of tubulin in the microtubule lattice

Yean-Ming Chew, Robert A. Cross
Journal: Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 161–171.
https://doi.org/10.1042/BST20240360
Published: 05 February 2025
View articletitled, Structural switching of tubulin in the microtubule lattice
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Articles

Exploring the influence of anionic lipids in the host cell membrane on viral fusion

Daniel Birtles, Jinwoo Lee
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2593–2602.
https://doi.org/10.1042/BST20240833
Published: 19 December 2024
View articletitled, Exploring the influence of anionic lipids in the host cell membrane on viral fusion
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Articles

The expanding roles of myonuclei in adult skeletal muscle health and function

Agnieszka K. Borowik, Kevin A. Murach, Benjamin F. Miller
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2603–2616.
https://doi.org/10.1042/BST20241637
Published: 19 December 2024
View articletitled, The expanding roles of myonuclei in adult skeletal muscle health and function
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Articles

Linking glycosphingolipid metabolism to disease-related changes in the plasma membrane proteome

Holly Monkhouse, Janet E. Deane
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2477–2486.
https://doi.org/10.1042/BST20240315
Published: 06 December 2024
View articletitled, Linking glycosphingolipid metabolism to disease-related changes in the plasma membrane proteome
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Articles

The integrin adhesome and control of anti-tumour immunity

Emily R. Webb, Annabel Black, Nicole D. Barth, Stefan N. Symeonides, Valerie G. Brunton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2455–2468.
https://doi.org/10.1042/BST20240386
Published: 06 December 2024
View articletitled, The integrin adhesome and control of anti-tumour immunity
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Articles

An update on the role of sex hormones in the function of the cardiorenal mitochondria

Anastasia S. Shulha, Vita Shyshenko, Ryan S. Schibalski, Adam C. Jones, Jessica L. Faulkner, Krisztian Stadler, Daria V. Ilatovskaya
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (6): 2307–2319.
https://doi.org/10.1042/BST20240046
Published: 27 November 2024
View articletitled, An update on the role of sex hormones in the function of the cardiorenal mitochondria
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Articles

Using human disease mutations to understand de novo DNA methyltransferase function

Willow Rolls, Marcus D. Wilson, Duncan Sproul
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2059–2075.
https://doi.org/10.1042/BST20231017
Published: 24 October 2024
View articletitled, Using human disease mutations to understand de novo DNA methyltransferase function
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Articles

The role of prokaryotic argonautes in resistance to type II topoisomerases poison ciprofloxacin

Alina Galivondzhyan, Dmitry Sutormin, Vladimir Panteleev, Andrey Kulbachinskiy, Konstantin Severinov
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2157–2166.
https://doi.org/10.1042/BST20240094
Published: 24 October 2024
View articletitled, The role of prokaryotic argonautes in resistance to type II topoisomerases poison ciprofloxacin
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Includes: Supplementary data
Articles

Understanding the role of ten-eleven translocation family proteins in kidney diseases

Yuelin Zhang, Jiahui Li, Li Tan, Jun Xue, Yujiang Geno Shi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2203–2214.
https://doi.org/10.1042/BST20240291
Published: 08 October 2024
View articletitled, Understanding the role of ten-eleven translocation family proteins in kidney diseases
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Articles

Coordinating BNIP3/NIX-mediated mitophagy in space and time

Natalie M. Niemi, Jonathan R. Friedman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 1969–1979.
https://doi.org/10.1042/BST20221364
Published: 08 October 2024
View articletitled, Coordinating BNIP3/NIX-mediated mitophagy in space and time
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Articles

Disruptions to protein kinase A localization in adrenal pathology

Mitchell H. Omar
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2231–2241.
https://doi.org/10.1042/BST20240444
Published: 04 October 2024
View articletitled, Disruptions to protein kinase A localization in adrenal pathology
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Articles

Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection

Jesse Pellman, Anna Goldstein, Mikołaj Słabicki
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2009–2021.
https://doi.org/10.1042/BST20230324
Published: 02 September 2024
View articletitled, Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection
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Articles

Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders

Amelia Bryers, Cheryl A. Hawkes, Edward Parkin, Neil Dawson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (5): 2047–2058.
https://doi.org/10.1042/BST20231004
Published: 02 September 2024
View articletitled, Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders
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Articles

Exploring the complexity of amyloid-beta fibrils: structural polymorphisms and molecular interactions

Yoongyeong Baek, Myungwoon Lee
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1631–1646.
https://doi.org/10.1042/BST20230854
Published: 19 July 2024
View articletitled, Exploring the complexity of amyloid-beta fibrils: structural polymorphisms and molecular interactions
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Articles

Roles for PMP22 in Schwann cell cholesterol homeostasis in health and disease

Katherine M. Stefanski, Mason C. Wilkinson, Charles R. Sanders
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1747–1756.
https://doi.org/10.1042/BST20231359
Published: 09 July 2024
View articletitled, Roles for PMP22 in Schwann cell cholesterol homeostasis in health and disease
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Articles

Androgen receptor post-translational modifications and their implications for pathology

Inés Montoya-Novoa, José Luis Gardeazábal-Torbado, Andrea Alegre-Martí, Pablo Fuentes-Prior, Eva Estébanez-Perpiñá
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1673–1694.
https://doi.org/10.1042/BST20231082
Published: 03 July 2024
View articletitled, Androgen receptor post-translational modifications and their implications for pathology
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Articles

TDP-43 in nuclear condensates: where, how, and why

Ruaridh Lang, Rachel E. Hodgson, Tatyana A. Shelkovnikova
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1809–1825.
https://doi.org/10.1042/BST20231447
Published: 03 July 2024
View articletitled, TDP-43 in nuclear condensates: where, how, and why
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Articles

Molecular aspects of Interleukin-36 cytokine activation and regulation

Jennifer Keller, James R. O’ Siorain, Thomas M. Kündig, Mark Mellett
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1591–1604.
https://doi.org/10.1042/BST20230548
Published: 28 June 2024
View articletitled, Molecular aspects of Interleukin-36 cytokine activation and regulation
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Articles

A second generation of senotherapies: the development of targeted senolytics, senoblockers and senoreversers for healthy ageing

Vinesh Dhokia, Amal Albati, Hannah Smith, Gethin Thomas, Salvador Macip
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1661–1671.
https://doi.org/10.1042/BST20231066
Published: 28 June 2024
View articletitled, A second generation of senotherapies: the development of targeted senolytics, senoblockers and senoreversers for healthy ageing
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Articles

The role of Matrin-3 in physiology and its dysregulation in disease

Macy L. Sprunger, Meredith E. Jackrel
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 961–972.
https://doi.org/10.1042/BST20220585
Published: 30 May 2024
View articletitled, The role of Matrin-3 in physiology and its dysregulation in disease
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Articles

The high-affinity tryptophan uptake transport system in human cells

Keisuke Wakasugi, Takumi Yokosawa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1149–1158.
https://doi.org/10.1042/BST20230742
Published: 30 May 2024
View articletitled, The high-affinity tryptophan uptake transport system in human cells
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Articles

Modification of extracellular matrix proteins by oxidants and electrophiles

Karen C. Yang-Jensen, Sara M. Jørgensen, Christine Y. Chuang, Michael J. Davies
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1199–1217.
https://doi.org/10.1042/BST20230860
Published: 23 May 2024
View articletitled, Modification of extracellular matrix proteins by oxidants and electrophiles
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Articles

ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity

Francesca Paoletti
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1293–1304.
https://doi.org/10.1042/BST20231089
Published: 08 May 2024
View articletitled, ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity
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Articles

Reprogrammed mitochondria: a central hub of cancer cell metabolism

Fabio Ciccarone, Maria Rosa Ciriolo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1305–1315.
https://doi.org/10.1042/BST20231090
Published: 08 May 2024
View articletitled, Reprogrammed mitochondria: a central hub of cancer cell metabolism
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Articles

Bone morphogenetic protein signalling in pulmonary arterial hypertension: revisiting the BMPRII connection

Wei Li, Kate Quigley
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1515–1528.
https://doi.org/10.1042/BST20231547
Published: 08 May 2024
View articletitled, Bone morphogenetic protein signalling in pulmonary arterial hypertension: revisiting the BMPRII connection
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Articles

Let's get fat: emergence of S -acylation as a therapeutic target in Huntington disease

Dale D.O. Martin, Shaun S. Sanders
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1385–1392.
https://doi.org/10.1042/BST20231290
Published: 02 May 2024
View articletitled, Let's get fat: emergence of S -acylation as a therapeutic target in Huntington disease
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Articles

Regulation of RAF family kinases: new insights from recent structural and biochemical studies

Russell Spencer-Smith, Deborah K. Morrison
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1061–1069.
https://doi.org/10.1042/BST20230552
Published: 02 May 2024
View articletitled, Regulation of RAF family kinases: new insights from recent structural and biochemical studies
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Articles

Atomic force microscopy 3D structural reconstruction of individual particles in the study of amyloid protein assemblies

Claudia Chitty, Kinga Kuliga, Wei-Feng Xue
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 761–771.
https://doi.org/10.1042/BST20230857
Published: 11 April 2024
View articletitled, Atomic force microscopy 3D structural reconstruction of individual particles in the study of amyloid protein assemblies
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Articles

Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation

Patrick C.A. van der Wel
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 719–731.
https://doi.org/10.1042/BST20230731
Published: 02 April 2024
View articletitled, Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation
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Articles

Emerging mechanisms in the redox regulation of mitochondrial cytochrome c oxidase assembly and function

Suleva Povea-Cabello, Michele Brischigliaro, Erika Fernández-Vizarra
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 873–885.
https://doi.org/10.1042/BST20231183
Published: 25 March 2024
View articletitled, Emerging mechanisms in the redox regulation of mitochondrial cytochrome c oxidase assembly and function
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Articles

Complex I activity in hypoxia: implications for oncometabolism

Christos Chinopoulos
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 529–538.
https://doi.org/10.1042/BST20230189
Published: 25 March 2024
View articletitled, Complex I activity in hypoxia: implications for oncometabolism
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Articles

CRISPRi: a way to integrate iPSC-derived neuronal models

Sarah N.J. Franks, Rachel Heon-Roberts, Brent J. Ryan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 539–551.
https://doi.org/10.1042/BST20230190
Published: 25 March 2024
View articletitled, CRISPRi: a way to integrate iPSC-derived neuronal models
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Articles

Beyond protein synthesis: non-translational functions of threonyl-tRNA synthetases

Pallob Barai, Jie Chen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 661–670.
https://doi.org/10.1042/BST20230506
Published: 13 March 2024
View articletitled, Beyond protein synthesis: non-translational functions of threonyl-tRNA synthetases
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Articles

Type III intermediate filaments in redox interplay: key role of the conserved cysteine residue

María A. Pajares, Dolores Pérez-Sala
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (2): 849–860.
https://doi.org/10.1042/BST20231059
Published: 07 March 2024
View articletitled, Type III intermediate filaments in redox interplay: key role of the conserved cysteine residue
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Articles

The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies

Gaurav Sharma, Martina Paganin, Fabio Lauria, Elena Perenthaler, Gabriella Viero
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 465–479.
https://doi.org/10.1042/BST20231116
Published: 23 February 2024
View articletitled, The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies
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Articles

The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections

In Collection
Coronavirus
Evangelos D. Karousis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 481–490.
https://doi.org/10.1042/BST20231119
Published: 22 February 2024
View articletitled, The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections
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Articles

Dietary nitrate supplementation and cognitive health: the nitric oxide-dependent neurovascular coupling hypothesis

João S. Gonçalves, Ana L. Marçal, Bárbara S. Marques, Filipa D. Costa, João Laranjinha, Bárbara S. Rocha, Cátia F. Lourenço
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 279–289.
https://doi.org/10.1042/BST20230491
Published: 22 February 2024
View articletitled, Dietary nitrate supplementation and cognitive health: the nitric oxide-dependent neurovascular coupling hypothesis
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Articles

Interactions between zinc and NRF2 in vascular redox signalling

Fan Yang, Matthew J. Smith, Richard C.M. Siow, Dag Aarsland, Wolfgang Maret, Giovanni E. Mann
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 269–278.
https://doi.org/10.1042/BST20230490
Published: 19 February 2024
View articletitled, Interactions between zinc and NRF2 in vascular redox signalling
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Articles

DDX41: exploring the roles of a versatile helicase

Lacey Winstone, Yohan Jung, Yuliang Wu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 395–405.
https://doi.org/10.1042/BST20230725
Published: 13 February 2024
View articletitled, DDX41: exploring the roles of a versatile helicase
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Articles

Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation

Harry Aldworth, Nigel M. Hooper
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 431–440.
https://doi.org/10.1042/BST20230918
Published: 08 February 2024
View articletitled, Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation
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Articles

Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD

Polett Garcés, Armando Amaro, Martin Montecino, Brigitte van Zundert
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 123–135.
https://doi.org/10.1042/BST20230257
Published: 07 February 2024
View articletitled, Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD
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Articles

Neurodevelopmental functions of CHD8: new insights and questions

M. Albert Basson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (1): 15–27.
https://doi.org/10.1042/BST20220926
Published: 30 January 2024
View articletitled, Neurodevelopmental functions of CHD8: new insights and questions
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Articles

Layered mechanisms regulating the human mitochondrial NAD + transporter SLC25A51

Shivansh Goyal, Xiaolu A. Cambronne
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (6): 1989–2004.
https://doi.org/10.1042/BST20220318
Published: 18 December 2023
View articletitled, Layered mechanisms regulating the human mitochondrial NAD + transporter SLC25A51
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Articles

The PDLIM family of actin-associated proteins and their emerging role in membrane trafficking

Michael D. Healy, Brett M. Collins
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (6): 2005–2016.
https://doi.org/10.1042/BST20220804
Published: 14 December 2023
View articletitled, The PDLIM family of actin-associated proteins and their emerging role in membrane trafficking
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Articles

Mechanisms of stress management in mitochondrial protein import

Maryam Mukhtar, Krutika Thakkur, Agnieszka Chacinska, Piotr Bragoszewski
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (6): 2117–2126.
https://doi.org/10.1042/BST20230377
Published: 21 November 2023
View articletitled, Mechanisms of stress management in mitochondrial protein import
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Articles

The expanding boundaries of sphingolipid lysosomal storage diseases; insights from Niemann–Pick disease type C

In Collection
Awards
Frances M. Platt
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1777–1787.
https://doi.org/10.1042/BST20220711
Published: 16 October 2023
View articletitled, The expanding boundaries of sphingolipid lysosomal storage diseases; insights from Niemann–Pick disease type C
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Articles

The role of peroxidasin in solid cancer progression

Kaitlin Wyllie, Vasilios Panagopoulos, Thomas R. Cox
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (5): 1881–1895.
https://doi.org/10.1042/BST20230018
Published: 06 October 2023
View articletitled, The role of peroxidasin in solid cancer progression
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Articles

Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels

Yi-Ling Wu, Ai-Hsing Yang, Yu-Hsin Chiu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1687–1699.
https://doi.org/10.1042/BST20230038
Published: 25 August 2023
View articletitled, Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels
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