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Articles

Regulation of neuronal ankyrin localization and function by post-translational modifications

Kalynn M. Bird, Paul M. Jenkins

Biochem Soc Trans (2025) 53 (02): 497–507.

https://doi.org/10.1042/BST20253016

Published: 30 April 2025

View articletitled, Regulation of neuronal ankyrin localization and function by post-translational modifications

Articles

Progress toward a comprehensive brain protein interactome

Vy Dang, Brittney Voigt, Edward M. Marcotte

Biochem Soc Trans (2025) 53 (01): 303–314.

https://doi.org/10.1042/BST20241135

Published: 12 February 2025

View articletitled, Progress toward a comprehensive brain protein interactome

Articles

The NMDAR-BK channelosomes as regulators of synaptic plasticity

Rebeca Martínez-Lazaro, Andrea Reyes-Carrión, David Bartolomé-Martín, Teresa Giraldez

Biochem Soc Trans (2025) 53 (01): 47–58.

https://doi.org/10.1042/BST20240425

Published: 28 January 2025

View articletitled, The NMDAR-BK channelosomes as regulators of synaptic plasticity

Articles

The AICD interactome: implications in neurodevelopment and neurodegeneration

Laura Lok-Haang Ng, Jessica Chow, Kwok-Fai Lau

Biochem Soc Trans (2024) 52 (6): 2539–2556.

https://doi.org/10.1042/BST20241510

Published: 13 December 2024

View articletitled, The AICD interactome: implications in neurodevelopment and neurodegeneration

Articles

Cellular mechanisms underlying pituitary adenylate cyclase activating polypeptide-stimulated secretion in the adrenal medulla

Nicole A. Bell, Xiaohuan Chen, David R. Giovannucci, Arun Anantharam

Biochem Soc Trans (2024) 52 (6): 2373–2383.

https://doi.org/10.1042/BST20231326

Published: 10 December 2024

View articletitled, Cellular mechanisms underlying pituitary adenylate cyclase activating polypeptide-stimulated secretion in the adrenal medulla

Articles

Age-dependent regenerative mechanisms in the brain

Giada Vanacore, Jens Bager Christensen, N. Sumru Bayin

Biochem Soc Trans (2024) 52 (6): 2243–2252.

https://doi.org/10.1042/BST20230547

Published: 25 November 2024

View articletitled, Age-dependent regenerative mechanisms in the brain

Articles

Voltage-clamp fluorometry for advancing mechanistic understanding of ion channel mechanisms with a focus on acid-sensing ion channels

Eleonora Centonze, Stephan Kellenberger

Biochem Soc Trans (2024) 52 (5): 2167–2177.

https://doi.org/10.1042/BST20240165

Published: 14 October 2024

View articletitled, Voltage-clamp fluorometry for advancing mechanistic understanding of ion channel mechanisms with a focus on acid-sensing ion channels

Articles

Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders

Amelia Bryers, Cheryl A. Hawkes, Edward Parkin, Neil Dawson

Biochem Soc Trans (2024) 52 (5): 2047–2058.

https://doi.org/10.1042/BST20231004

Published: 02 September 2024

View articletitled, Progress towards understanding risk factor mechanisms in the development of autism spectrum disorders

Articles

Interplay of mitochondrial calcium signalling and reactive oxygen species production in the brain

Plamena R. Angelova, Andrey Y. Abramov

Biochem Soc Trans (2024) 52 (4): 1939–1946.

https://doi.org/10.1042/BST20240261

Published: 22 August 2024

View articletitled, Interplay of mitochondrial calcium signalling and reactive oxygen species production in the brain

Articles

Exploring the structural dynamics of the vesicle priming machinery

Dong An, Manfred Lindau

Biochem Soc Trans (2024) 52 (4): 1715–1725.

https://doi.org/10.1042/BST20231333

Published: 31 July 2024

View articletitled, Exploring the structural dynamics of the vesicle priming machinery

Articles

Mechanisms of lysosomal tubulation and sorting driven by LRRK2

Luis Bonet-Ponce, Jillian H. Kluss, Mark R. Cookson

Biochem Soc Trans (2024) 52 (4): 1909–1919.

https://doi.org/10.1042/BST20240087

Published: 31 July 2024

View articletitled, Mechanisms of lysosomal tubulation and sorting driven by LRRK2

Articles

Roles for PMP22 in Schwann cell cholesterol homeostasis in health and disease

Katherine M. Stefanski, Mason C. Wilkinson, Charles R. Sanders

Biochem Soc Trans (2024) 52 (4): 1747–1756.

https://doi.org/10.1042/BST20231359

Published: 09 July 2024

View articletitled, Roles for PMP22 in Schwann cell cholesterol homeostasis in health and disease

Articles

TDP-43 in nuclear condensates: where, how, and why

Ruaridh Lang, Rachel E. Hodgson, Tatyana A. Shelkovnikova

Biochem Soc Trans (2024) 52 (4): 1809–1825.

https://doi.org/10.1042/BST20231447

Published: 03 July 2024

View articletitled, TDP-43 in nuclear condensates: where, how, and why

Articles

Calcium channel signalling at neuronal endoplasmic reticulum-plasma membrane junctions

Filip Maciąg, Arun Chhikara, Martin Heine

Biochem Soc Trans (2024) 52 (4): 1617–1629.

https://doi.org/10.1042/BST20230819

Published: 27 June 2024

View articletitled, Calcium channel signalling at neuronal endoplasmic reticulum-plasma membrane junctions

Articles

Biomarkers for aging in Caenorhabditis elegans high throughput screening

Victoria R. Yarmey, Adriana San-Miguel

Biochem Soc Trans (2024) 52 (3): 1405–1418.

https://doi.org/10.1042/BST20231303

Published: 17 June 2024

View articletitled, Biomarkers for aging in Caenorhabditis elegans high throughput screening

Articles

The role of Matrin-3 in physiology and its dysregulation in disease

Macy L. Sprunger, Meredith E. Jackrel

Biochem Soc Trans (2024) 52 (3): 961–972.

https://doi.org/10.1042/BST20220585

Published: 30 May 2024

View articletitled, The role of Matrin-3 in physiology and its dysregulation in disease

Articles

Dopamine synthesis and transport: current and novel therapeutics for parkinsonisms

Mary Dayne Sia Tai, Gloria Gamiz-Arco, Aurora Martinez

Biochem Soc Trans (2024) 52 (3): 1275–1291.

https://doi.org/10.1042/BST20231061

Published: 30 May 2024

View articletitled, Dopamine synthesis and transport: current and novel therapeutics for parkinsonisms

Articles

Nano-organization of synaptic calcium signaling

Clara I. McCarthy, Ege T. Kavalali

Biochem Soc Trans (2024) 52 (3): 1459–1471.

https://doi.org/10.1042/BST20231385

Published: 16 May 2024

View articletitled, Nano-organization of synaptic calcium signaling

Articles

Deubiquitinases in muscle physiology and disorders

Cyriel S. Olie, Darragh P. O'Brien, Hannah B.L. Jones, Zhu Liang, Andreas Damianou, Ilknur Sur-Erdem, Adán Pinto-Fernández, Vered Raz, Benedikt M. Kessler

Biochem Soc Trans (2024) 52 (3): 1085–1098.

https://doi.org/10.1042/BST20230562

Published: 08 May 2024

View articletitled, Deubiquitinases in muscle physiology and disorders

Articles

Retrotransposons in embryogenesis and neurodevelopment

Mary Jo Talley, Michelle S. Longworth

Biochem Soc Trans (2024) 52 (3): 1159–1171.

https://doi.org/10.1042/BST20230757

Published: 08 May 2024

View articletitled, Retrotransposons in embryogenesis and neurodevelopment

Articles

ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity

Francesca Paoletti

Biochem Soc Trans (2024) 52 (3): 1293–1304.

https://doi.org/10.1042/BST20231089

Published: 08 May 2024

View articletitled, ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity

Articles

Let's get fat: emergence of S -acylation as a therapeutic target in Huntington disease

Dale D.O. Martin, Shaun S. Sanders

Biochem Soc Trans (2024) 52 (3): 1385–1392.

https://doi.org/10.1042/BST20231290

Published: 02 May 2024

View articletitled, Let's get fat: emergence of S -acylation as a therapeutic target in Huntington disease

Articles

Exploring potential developmental origins of common neurodegenerative disorders

James P. Catlin, Christine E. Schaner Tooley

Biochem Soc Trans (2024) 52 (3): 1035–1044.

https://doi.org/10.1042/BST20230422

Published: 25 April 2024

View articletitled, Exploring potential developmental origins of common neurodegenerative disorders

Articles

Mechanically operated signalling scaffolds

Neil J. Ball, Samuel F. H. Barnett, Benjamin T. Goult

Biochem Soc Trans (2024) 52 (2): 517–527.

https://doi.org/10.1042/BST20221194

Published: 04 April 2024

View articletitled, Mechanically operated signalling scaffolds

Articles

Delineating mechanisms underlying parvalbumin neuron impairment in different neurological and neurodegenerative disorders: the emerging role of mitochondrial dysfunction

Elizaveta A. Olkhova, Laura A. Smith, Bethany H. Dennis, Yi Shiau Ng, Fiona E. N. LeBeau, Gráinne S. Gorman

Biochem Soc Trans (2024) 52 (2): 553–565.

https://doi.org/10.1042/BST20230191

Published: 02 April 2024

View articletitled, Delineating mechanisms underlying parvalbumin neuron impairment in different neurological and neurodegenerative disorders: the emerging role of mitochondrial dysfunction

Articles

CRISPRi: a way to integrate iPSC-derived neuronal models

Sarah N.J. Franks, Rachel Heon-Roberts, Brent J. Ryan

Biochem Soc Trans (2024) 52 (2): 539–551.

https://doi.org/10.1042/BST20230190

Published: 25 March 2024

View articletitled, CRISPRi: a way to integrate iPSC-derived neuronal models

Articles

How does the neuronal proteostasis network react to cellular cues?

Ki Hong Nam, Alban Ordureau

Biochem Soc Trans (2024) 52 (2): 581–592.

https://doi.org/10.1042/BST20230316

Published: 15 March 2024

View articletitled, How does the neuronal proteostasis network react to cellular cues?

Articles

Transcriptional control of neural stem cell activity

Takashi Kaise, Ryoichiro Kageyama

Biochem Soc Trans (2024) 52 (2): 617–626.

https://doi.org/10.1042/BST20230439

Published: 13 March 2024

View articletitled, Transcriptional control of neural stem cell activity

Articles

The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies

Gaurav Sharma, Martina Paganin, Fabio Lauria, Elena Perenthaler, Gabriella Viero

Biochem Soc Trans (2024) 52 (1): 465–479.

https://doi.org/10.1042/BST20231116

Published: 23 February 2024

View articletitled, The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies

Articles

Dietary nitrate supplementation and cognitive health: the nitric oxide-dependent neurovascular coupling hypothesis

João S. Gonçalves, Ana L. Marçal, Bárbara S. Marques, Filipa D. Costa, João Laranjinha, Bárbara S. Rocha, Cátia F. Lourenço

Biochem Soc Trans (2024) 52 (1): 279–289.

https://doi.org/10.1042/BST20230491

Published: 22 February 2024

View articletitled, Dietary nitrate supplementation and cognitive health: the nitric oxide-dependent neurovascular coupling hypothesis

Articles

Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein

Mohammed M. Alhadidy, Nicholas M. Kanaan

Biochem Soc Trans (2024) 52 (1): 301–318.

https://doi.org/10.1042/BST20230596

Published: 13 February 2024

View articletitled, Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein

Articles

Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD

Polett Garcés, Armando Amaro, Martin Montecino, Brigitte van Zundert

Biochem Soc Trans (2024) 52 (1): 123–135.

https://doi.org/10.1042/BST20230257

Published: 07 February 2024

View articletitled, Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD

Articles

Induced-pluripotent stem cells and neuroproteomics as tools for studying neurodegeneration

Caroline Brandão-Teles, Giuliana S. Zuccoli, Talita Aparecida de Moraes Vrechi, Lívia Ramos-da-Silva, Aline Valéria Sousa Santos, Fernanda Crunfli, Daniel Martins-de-Souza

Biochem Soc Trans (2024) 52 (1): 163–176.

https://doi.org/10.1042/BST20230341

Published: 30 January 2024

View articletitled, Induced-pluripotent stem cells and neuroproteomics as tools for studying neurodegeneration

Articles

Neurodevelopmental functions of CHD8: new insights and questions

M. Albert Basson

Biochem Soc Trans (2024) 52 (1): 15–27.

https://doi.org/10.1042/BST20220926

Published: 30 January 2024

View articletitled, Neurodevelopmental functions of CHD8: new insights and questions

Articles

Genetic regulation of enteric nervous system development in zebrafish

Rosa A. Uribe

Biochem Soc Trans (2024) 52 (1): 177–190.

https://doi.org/10.1042/BST20230343

Published: 04 January 2024

View articletitled, Genetic regulation of enteric nervous system development in zebrafish

Articles

Chemical catalysis by biological amyloids

Pernilla Wittung-Stafshede

Biochem Soc Trans (2023) 51 (5): 1967–1974.

https://doi.org/10.1042/BST20230617

Published: 25 September 2023

View articletitled, Chemical catalysis by biological amyloids

Articles

Structural and functional insights into the G protein-coupled receptors: CB1 and CB2

Christina A. Brust, Matthew A. Swanson, Laura M. Bohn

Biochem Soc Trans (2023) 51 (4): 1533–1543.

https://doi.org/10.1042/BST20221316

Published: 10 August 2023

View articletitled, Structural and functional insights into the G protein-coupled receptors: CB1 and CB2

Articles

Functions and mechanisms of the GPCR adaptor protein Norbin

Stephen A. Chetwynd, Simon Andrews, Sarah Inglesfield, Christine Delon, Nicholas T. Ktistakis, Heidi C. E. Welch

Biochem Soc Trans (2023) 51 (4): 1545–1558.

https://doi.org/10.1042/BST20221349

Published: 28 July 2023

View articletitled, Functions and mechanisms of the GPCR adaptor protein Norbin

Articles

γ-Secretase fanning the fire of innate immunity

Chenge Liu, Cyrus Nikain, Yue-Ming Li

Biochem Soc Trans (2023) 51 (4): 1597–1610.

https://doi.org/10.1042/BST20221445

Published: 14 July 2023

View articletitled, γ-Secretase fanning the fire of innate immunity

Articles

Amyloid precursor protein and its interacting proteins in neurodevelopment

Dennis Dik-Long Chau, Laura Lok-Haang Ng, Yuqi Zhai, Kwok-Fai Lau

Biochem Soc Trans (2023) 51 (4): 1647–1659.

https://doi.org/10.1042/BST20221527

Published: 30 June 2023

View articletitled, Amyloid precursor protein and its interacting proteins in neurodevelopment

Articles

Pleiotropy of C1QL proteins across physiological systems and their emerging role in synapse homeostasis

Perla A. Peña Palomino, Kylie C. Black, Susanne Ressl

Biochem Soc Trans (2023) 51 (3): 937–947.

https://doi.org/10.1042/BST20220439

Published: 04 May 2023

View articletitled, Pleiotropy of C1QL proteins across physiological systems and their emerging role in synapse homeostasis

Articles

What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides

Yasushi Okamura, Daisuke Yoshioka

Biochem Soc Trans (2023) 51 (2): 827–839.

https://doi.org/10.1042/BST20221065

Published: 13 April 2023

View articletitled, What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides

Articles

CHCHD2 and CHCHD10-related neurodegeneration: molecular pathogenesis and the path to precision therapy

Mario K. Shammas, Tzu-Hsiang Huang, Derek P. Narendra

Biochem Soc Trans (2023) 51 (2): 797–809.

https://doi.org/10.1042/BST20221365

Published: 06 April 2023

View articletitled, CHCHD2 and CHCHD10-related neurodegeneration: molecular pathogenesis and the path to precision therapy

Articles

The muscarinic M 4 acetylcholine receptor exacerbates symptoms of movement disorders

Nicole E. Chambers, Michael Millett, Jr, Mark S. Moehle

Biochem Soc Trans (2023) 51 (2): 691–702.

https://doi.org/10.1042/BST20220525

Published: 04 April 2023

View articletitled, The muscarinic M 4 acetylcholine receptor exacerbates symptoms of movement disorders

Articles

The interplay between monocytes, α-synuclein and LRRK2 in Parkinson's disease

Samuel Strader, Andrew B. West

Biochem Soc Trans (2023) 51 (2): 747–758.

https://doi.org/10.1042/BST20201091

Published: 04 April 2023

View articletitled, The interplay between monocytes, α-synuclein and LRRK2 in Parkinson's disease

Articles

Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation

Rachel Fasiczka, Yahaira Naaldijk, Besma Brahmia, Sabine Hilfiker

Biochem Soc Trans (2023) 51 (2): 587–595.

https://doi.org/10.1042/BST20201145

Published: 17 March 2023

View articletitled, Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation

Articles

The role of the blood–brain barrier during neurological disease and infection

Adjanie Patabendige, Damir Janigro

Biochem Soc Trans (2023) 51 (2): 613–626.

https://doi.org/10.1042/BST20220830

Published: 17 March 2023

View articletitled, The role of the blood–brain barrier during neurological disease and infection

Articles

Modulation of chromatin architecture influences the neuronal nucleus through activity-regulated gene expression

Robert S. Porter, Shigeki Iwase

Biochem Soc Trans (2023) 51 (2): 703–713.

https://doi.org/10.1042/BST20220889

Published: 16 March 2023

View articletitled, Modulation of chromatin architecture influences the neuronal nucleus through activity-regulated gene expression

Articles

The role of PQBP1 in neural development and function

Shanshan Cheng, Xian Liu, Linjuan Yuan, Nan Wang, Zi Chao Zhang, Junhai Han

Biochem Soc Trans (2023) 51 (1): 363–372.

https://doi.org/10.1042/BST20220920

Published: 23 February 2023

View articletitled, The role of PQBP1 in neural development and function

Articles

Protective mechanisms by glial cell line-derived neurotrophic factor and cerebral dopamine neurotrophic factor against the α-synuclein accumulation in Parkinson's disease

Safak Er, Mikko Airavaara

Biochem Soc Trans (2023) 51 (1): 245–257.

https://doi.org/10.1042/BST20220770

Published: 16 February 2023

View articletitled, Protective mechanisms by glial cell line-derived neurotrophic factor and cerebral dopamine neurotrophic factor against the α-synuclein accumulation in Parkinson's disease

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