... fatty acid synthesis ACC, acetyl-CoA carboxylase AICAR, 5-aminoimidazole-4-carboxamide ribonucleoside AMPK, AMP-activated protein kinase CPTI, carnitine palmitoyltransferase-l PKA, cAMP-dependent protein kinase It is clear that down-regulation of a specific component of lipid metabolism...

... should be addressed at Wellcome Trust Biocentre, Dundee University, Dow Street, Dundee DDI 5EH, U.K. (e-mail: [email protected] ) 18 7 2002 © 2002 Biochemical Society 2002 ACC, acetyl-CoA carboxylase AICA, 5-aminoimidazole-4-carboxamide AMPK, AMP-activated protein kinase...

... expression, glucose, pancreatic p-cell Abbreviations used: ACC, acetyl-CoA carboxylase; Ada I DN, adenovirus encoding a dominant negative form of the a I -subunit of AMPK; AICAR, 5-aminoimidazole-4-carboxamide riboside: AMPK, AMP-activated protein kinase; FAS, fatty acid synthase; GK, glucokinase; GLUT...

..., glucose homeostasis. Abbreviations used : ACC, acetyl-CoA carboxylase; FAS, fatty-acid synthase; GK. glucokinase; L-PK. L-type pyruvate kinase; MAP, enzymes) and inhibits genes for enzymes involved in glucose production (phosphenolpyruvate car- boxykinase). The mechanisms by which insulin controls...

... is also addressed briefly. 1 e-mail: [email protected] 7 11 2000 © 2001 Biochemical Society 2001 fatty acid oxidation fuel homoeostasis malonyl-CoA sperm development ACC, acetyl-CoA carboxylase CPT, carnitine palmitoyltransferase Et-CoA, etomoxir-CoA...

... of acetyl-CoA by acetyl-CoA carboxylase (ACC) is well charac- terized, how acetyl-CoA is generated within plas- Key words: fatty acid biosynthesis, malonyl-CoA. Abbreviations used: ACC, acetyl-CoA carboxylase; ACL, ATP- citrate lyase; ACS. acetyl-CoA synthetase; ALDH, aldehyde dehydrogenase; PDC, pyruvate...

...D. G. Hardie; J. Corton; Y. P. Ching; S. P. Davies; S. Hawley 5 8 1997 © 1997 Biochemical Society 1997 AMPK, AMP-activated protein kinase AMPKK, AMPK kinase ACC, acetyl-CoA carboxylase AICA, 5-aminoimidazole-4-carboxamide HMGR, 3-hydroxy-3-methylglutaryl-CoA reductase...

...R. W. Brownsey; R. Zhande; A. N. Boone 1 To whom correspondence should be addressed 11 7 1997 © 1997 Biochemical Society 1997 ACC, acetyl-CoA carboxylase FAS, fatty acid synthase CPT-I, carnitine palmitoyl transferase I BCCP, biotin carboxyl carrier protein AMP-PK...

...R. M. Denton; K. J. Heesom; S. K. Moule; N. J. Edgell; P. Burnett 1 To whom correspondence should be addressed 30 6 1997 © 1997 Biochemical Society 1997 ACC, acetyl-CoA carboxylase PDH, pyruvate dehydrogenase ERK, extracellular signal-related protein kinase EGF...

...K.-S. Kim; J.-K. Lee; K.-H. Kim 23 6 1997 © 1997 Biochemical Society 1997 ACC, acetyl-CoA carboxylase PI, ACC gene promoter I PII, ACC gene promoter II CPT-I, carnitine palmitoyl-CoA transferase I KIC, ketoisocaproate RSV, Rous sarcoma virus CK, creatinine kinase...

...M. T. Travers; M. C. Barber 1 To whom correspondence should be addressed 27 6 1997 © 1997 Biochemical Society 1997 ACC, acetyl-CoA carboxylase PI, ACC gene promoter I PII, ACC gene promoter II Molecular Aspects of the Regulation of Lipid Biosynthesis 194145...

...F. Foufelle; J. Girard; P. Ferré ‡ To whom correspondence should be addressed 30 11 1995 © 1996 Biochemical Society 1996 ACC, acetyl-CoA carboxylase FAS, fatty acid synthase L-PK, L-pyruvate kinase G-6-PDH, glucose-6-phosphate dehydrogenase Biochemical Society...

...J. D. McGarry 28 2 1995 © 1995 Biochemical Society 1995 ACC, acetyl-CoA carboxylase CPT I and II, carnitine palmitoyltransferase I and II GSIS, glucose-stimulated insulin secretion HC, (-)-hydroxycitrate L-CPT I, liver CPT I M-CPT I, muscle CPT I Ketogenesis...

...V. A. Zammit 24 2 1995 © 1995 Biochemical Society 1995 ACC, acetyl-CoA carboxylase apoB, apolipoprotein B CPT I, carnitine palmitoyltransferase DAG, diacylglycerol GPAT, glycerol-3-phosphate acyltransferase PDH, pyruvate dehydrogenase TAG, triacylglycerol VLDL, very-low...

...MARGARET E. GRAHAM; ERIC FINLEY; RICHARD G. VERNON 22 11 1989 © 1990 Biochemical Society 1990 PDH, pyruvate dehydrogenase ACC, acetyl-CoA carboxylase PRL, prolactin GH, growth hormone BCR, bromocryptine AGS, anti-(rat growth hormone) serum 633rd Meeting London...

...I. MULLANEY; R. A. CLEGG; D. W. WEST; R. A. W. SMITH; B. MIDDLETON 27 11 1986 © 1987 Biochemical Society 1987 HMG, 3-hydroxy-4-methylglutaryl ACC, acetyl-CoA carboxylase 621st Meeting Held at University College, London: 621st Meeting Held at University College, London...