... significant mechanism in intact cells. 1 To whom correspondence should be addressed (email d.g.hardie@dundee.ac.uk ). 14 10 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 acetyl-CoA carboxylase (ACC) AMP-activated protein kinase (AMPK) Ca 2+ /calmodulin...

..., the initial phase of autophagosome formation. This is then elongated through the action of the Atg12–Atg5–Atg16L complex (reviewed in [ 22 ]). The present review focuses solely on the ULK1 complex as a point of autophagy regulation. AMP-activated protein kinase (AMPK) autophagy feedback mammalian...

... ). 7 12 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 AMP-activated protein kinase (AMPK) cancer inflammation innate immunity metabolism AMPK (AMP-activated protein kinase) is a highly conserved sensor of cellular energy status that exists in the form...

... nucleotides. This turned out to be correct, but what Atkinson did not anticipate was that sensing of nucleotides would, in most cases, be performed not by the metabolic enzymes themselves, but by a signalling protein, AMPK (AMP-activated protein kinase). AMPK occurs in essentially all eukaryotes and consists...

... motor function. 1 To whom correspondence should be addressed (email g.rutter@imperial.ac.uk ). 27 4 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 AMP-activated protein kinase (AMPK) four-dimensional confocal imaging insulin secretion kinesin...

... and other approaches that have been consistently challenging and immensely rewarding. 1 To whom correspondence should be addressed (email rogerb@interchange.ubc.ca ). 12 10 2005 © 2006 The Biochemical Society 2006 acetyl-CoA carboxylase (ACC) AMP-activated protein kinase (AMPK...

...N. Musi; H. Yu; L.J. Goodyear Physical exercise increases muscle glucose uptake, enhances insulin sensitivity and leads to fatty acid oxidation in muscle. The AMP-activated protein kinase (AMPK) is an energy-sensing enzyme that is strongly activated during muscle contraction due to acute decreases...