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Keywords: AU-rich element (ARE)
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Articles
Post-transcriptional regulation of gene expression in response to iron deficiency: co-ordinated metabolic reprogramming by yeast mRNA-binding proteins
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (5): 1088–1090.
Published: 19 September 2008
... proteins has been demonstrated to bind specifically to consensus RNA sequences that are AU-rich and thus are termed AREs (AU-rich elements). Mammalian TTP binds to ARE elements within the 3′-UTR (untranslated region) of the TNFα (tumour necrosis factor α) mRNA, strongly stimulating its turnover via...
