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Keyword: Alzheimer's disease (AD)
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Articles
Biochem Soc Trans (2012) 40 (4): 711-715.
Published: 20 July 2012
... with AD or whether it rather reflects non-specific neuronal damage. 1 To whom correspondence should be addressed (email j.attems@ncl.ac.uk ). 2 2 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 Alzheimer's disease (AD) Braak stages brainstem...
Articles
Biochem Soc Trans (2011) 39 (4): 898-901.
Published: 20 July 2011
... Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) central nervous system (CNS) microglial cell systemic inflammation In humans, evidence of communication between systemic inflammation and the CNS (central nervous system) is...
Articles
Biochem Soc Trans (2011) 39 (4): 868-873.
Published: 20 July 2011
... bind to ABAD, using a thermal shift assay. 1 To whom correspondence should be addressed (email fjg1@st-andrews.ac.uk ). 6 12 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid-binding alcohol dehydrogenase (ABAD...
Articles
Biochem Soc Trans (2011) 39 (4): 857-861.
Published: 20 July 2011
... compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) amyloid precursor protein (APP) human pathology intraneuronal amyloid β-peptide (intraneuronal Aβ) neuron loss AD (Alzheimer's disease) represents the most frequent form of dementia and is...
Articles
Biochem Soc Trans (2011) 39 (4): 891-897.
Published: 20 July 2011
... christian_holscher@mac.com 11 12 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) central nervous system (CNS) glucagon-like peptide-1 (GLP1) insulin receptor substrate (IRS) Type 2 diabetes mellitus (T2DM) AD (Alzheimer's disease) is a...
Articles
Biochem Soc Trans (2011) 39 (4): 874-880.
Published: 20 July 2011
... correspondence should be addressed (email b.platt@abdn.ac.uk ). 16 3 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) imaging positron-emission tomography (PET) power spectrum quantitative electroencephalogram sleep Translational...
Articles
Biochem Soc Trans (2011) 39 (4): 902-909.
Published: 20 July 2011
... (what, where and when) memory in mice. 1 To whom correspondence should be addressed (email Good@cardiff.ac.uk ). 2 5 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) dentate gyrus (DG) episodic-like...
Articles
Biochem Soc Trans (2011) 39 (4): 881-885.
Published: 20 July 2011
... © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) axon–glial integrity hypoperfusion vascular disease white matter The integrity of the white matter is critical in regulating efficient neuronal communication and...
Articles
Biochem Soc Trans (2011) 39 (4): 939-944.
Published: 20 July 2011
... daniela.carnevale@neuromed.it ). 6 12 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) amyloid β-peptide (Aβ) arterial hypertension lipopolysaccharide murine model AD is the leading cause of dementia in the elderly and, although some...
Articles
Biochem Soc Trans (2011) 39 (4): 917-919.
Published: 20 July 2011
... Alzheimer's disease (AD) amyloid deposit chronic neurodegenerative disease gliosis neuron Chronic neurodegenerative diseases including Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease are characterized by the neuropathological features of deposits of so-called amyloidogenic...
Articles
Biochem Soc Trans (2011) 39 (4): 945-953.
Published: 20 July 2011
... inflammation is a major contributor to the progression of dementia and constitutes an important clinical target. 1 email colm.cunningham@tcd.ie 19 1 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) animal model delirium dementia...
Articles
Biochem Soc Trans (2011) 39 (4): 924-932.
Published: 20 July 2011
... detrimental effects. 1 email yhuang@gladstone.ucsf.edu 27 2 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 Alzheimer's disease (AD) animal model apolipoprotein E (apoE) cognitive impairment neurodegeneration AD (Alzheimer's disease) causes...
Articles
Biochem Soc Trans (2010) 38 (1): 150-155.
Published: 19 January 2010
... potentially influence neurodegeneration. 1 To whom correspondence should be addressed (e-mail mikko.hiltunen@uku.fi ). 1 7 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 aggresome Alzheimer's disease (AD) presenilin proteasome protein aggregation...
Articles
Biochem Soc Trans (2005) 33 (5): 1096-1100.
Published: 26 October 2005
... 2005 © 2005 The Biochemical Society 2005 Alzheimer's disease (AD) amyloid precursor protein (APP) β-site amyloid precursor protein-cleaving enzyme (BACE) cholesterol platelet post-mortem brain protease Aβ peptides are found aggregated in the cortical amyloid plaques associated...
Articles
Biochem Soc Trans (2005) 33 (5): 1033-1036.
Published: 26 October 2005
... point to a convergence at the biochemical level between pathways involved in AD and those important for normal memory. 1 To whom correspondence should be addressed (email tjnelson@brni-jhu.org ). 17 6 2005 © 2005 The Biochemical Society 2005 Alzheimer's disease (AD) β-amyloid...
Articles
Biochem Soc Trans (2005) 33 (5): 1116-1118.
Published: 26 October 2005
... The Biochemical Society 2005 Alzheimer's disease (AD) amyloid precursor protein (APP) BACE1 (β-secretase 1) fibrillogenesis glycosaminoglycan (GAG) heparan sulphate (HS) AD is characterized by amyloid brain deposits of Aβ (amyloid β-peptide), formed by the cleavage of APP (amyloid...
Articles
Biochem Soc Trans (1998) 26 (3): S245.
Published: 01 August 1998
...Sarah L. Houldsworth; Alison J. Trew; Nigel M. Hooper; Anthony J. Turner © 1998 Biochemical Society 1998 Alzheimer's disease (AD) β-amyloid protein (βA4) β-amyloid precursor protein (β-APP) angiotensin converting enzyme (ACE) Hip, hippuryl 665th Meeting Southampton: 665th...
Articles
Biochem Soc Trans (1993) 21 (1): 18S.
Published: 01 February 1993
...RUTH M. DUBERLEY; CAROLE R. RICKARDS; JACK HAM; MAURICE F. SCANLON © 1993 Biochemical Society 1993 Alzheimer's Disease (AD) N-methyl-D-aspartate (NMDA) Kainic acid (KA) Quisqualate (Q) Choline acetyltransferase (CHAT) muscarinic acetylcholine receptor (mAchr) inositol monophosphate...