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Keywords: BCL-2 proteins
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Articles

Last but not least: BFL-1 as an emerging target for anti-cancer therapies

Open Access
Gaoyuan Wang, Sarah T. Diepstraten, Marco J. Herold
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1119–1128.
https://doi.org/10.1042/BST20220153
Published: 28 July 2022
...Gaoyuan Wang; Sarah T. Diepstraten; Marco J. Herold BFL-1 is an understudied pro-survival BCL-2 protein. The expression of BFL-1 is reported in many cancers, but it is yet to be clarified whether high transcript expression also always correlates with a pro-survival function. However, recent...
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Articles

Mechanisms of mitochondrial cell death

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Cell death and survival
Shashank Dadsena, Cristiana Zollo, Ana J. García-Sáez
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 663–674.
https://doi.org/10.1042/BST20200522
Published: 11 March 2021
... contributed equally to this work. 15 12 2020 26 1 2021 28 1 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 apoptosis BCL-2 proteins interorganelle interaction membrane dynamics MOMP pro-inflammatory signaling...
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