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Keywords: CHK1
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 207–221.
Published: 06 January 2023
... resection and promote NHEJ that would be fatal with this type of DS end [ 13 , 18 ]. These resected DSBs also activate the DDR cell cycle checkpoint kinases: ATR, CHK1 and WEE1 [ 19 ]. BRCA2 recruits RAD51 to allow invasion of the complementary chromatid template for high fidelity template-directed repair...