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Keywords: DCM
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Biochem Soc Trans (2018) 46 (3): 669–681.
Published: 21 May 2018
... © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 DCM EDMD mouse models nesprin Nesprins (nuclear envelope spectrin repeat proteins) are the latest identified members of the spectrin repeat (SR)-containing protein family [ 1 ]. To date...
Biochem Soc Trans (2018) 46 (2): 311–320.
Published: 27 February 2018
... of Nucleoskeleton and Cytoskeleton (LINC) complex at the nuclear envelope in association with lamin A/C and emerin. Mutations in nesprin-1/2 have been found in patients with autosomal dominant Emery–Dreifuss muscular dystrophy (EDMD) as well as dilated cardiomyopathy (DCM). Several lines of evidence...