Page 1 | Search Results | Biochemical Society Transactions

Skip Nav Destination

1-25 of 25

Sort by

Sort Order Select

Articles

Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

A. Kotlyarov, M. Gaestel

Biochem Soc Trans (2002) 30 (6): 959–963.

https://doi.org/10.1042/bst0300959

Published: 01 November 2002

... cytokine mouse knockout protein phosphorylation tumour necrosis factor ARE, AU-rich element CHOP, cAMP response element-binding protein-homologous protein: Hsp, heat-shock protein IL, interleukin LPS, lipopolysaccharide MAPK, mitogen-activated protein kinase MK2, mitogen-activated protein...

View article titled, Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

Articles

Adrenomedullin: receptor and signal transduction

D. M. Smith, H. A. Coppock, D. J. Withers, A. A. Owji, D. L. Hay, T. P. Choksi, P. Chakravarty, S. Legon, D. R. Poyne

Biochem Soc Trans (2002) 30 (4): 432–437.

https://doi.org/10.1042/bst0300432

Published: 01 August 2002

... (RAMP) type II G-protein-coupled receptor (GPCR) CGRP, calcitonin-gene-related peptide CRLR, calcitonin-receptor-like receptor GPCR, G-protein-coupled receptor MAPK, mitogen-activated protein kinase PDGF, platelet-derived growth factor RAMP, receptor-activity-modifying protein Biochemical...

View article titled, Adrenomedullin: receptor and signal transduction

Articles

Coagulation proteases and human cancer

M. T. Sampson, A. K. Kakkar

Biochem Soc Trans (2002) 30 (2): 201–207.

https://doi.org/10.1042/bst0300201

Published: 01 April 2002

... GPI, glycosylphosphatidylinositol MAPK, mitogen-activated protein kinase PAR, protease-activated receptor TF, tissue factor TFPI, tissue factor pathway inhibitor TSP, thrombospondin uPAR, urokinase-type plasminogen activator receptor VEC, vascular endothelial cell VEGF, vascular endothelial...

View article titled, Coagulation proteases and human cancer

Articles

Statins for the prevention of vein graft stenosis: a role for inhibition of matrix metalloproteinase-9

K. E. Porter, N. A. Turner

Biochem Soc Trans (2002) 30 (2): 120–126.

https://doi.org/10.1042/bst0300120

Published: 01 April 2002

[email protected] ). 8 11 2001 © 2002 Biochemical Society 2002 FCS, foetal calf serum FPP, famesyl pyrophosphate GGPP, geranylgeranyl pyrophosphate HMG-CoA, 3-hydroxy-3-methylglutaryl-CoA IH, intimal hyperplasia MAPK, mitogen-activated protein kinase MMP, matrix metalloproteinase NF- K B...

View article titled, Statins for the prevention of vein graft stenosis: a role for inhibition of matrix metalloproteinase-9

Articles

Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents

D. M. Zisterer, M. M. McGee, G. Campiani, A. Ramunno, C. Fattorusso, V. Nacci, M. Lawler, D. C. Williams

Biochem Soc Trans (2001) 29 (6): 704–706.

https://doi.org/10.1042/bst0290704

Published: 01 November 2001

... correspondence should be addressed (e-mail [email protected] ). 25 5 2001 © 2001 Biochemical Society 2001 apoptosis caspases c-Jun N-terminal kinase pyrrolo-1,5-benzoxazepines ATF2, activating transcription factor 2 JNK, c-Jun N-terminal kinase MAPK, mitogen-activated protein kinase...

View article titled, Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents

Articles

Internalization of the epidermal growth factor receptor: role in signalling

A. Sorkin

Biochem Soc Trans (2001) 29 (4): 480–484.

https://doi.org/10.1042/bst0290480

Published: 01 August 2001

... energy transfer FRET c , corrected FRET Grb2, growth-factor-receptor-bound protein 2 MAPK, mitogen-activated protein kinase PAE, porcine aortic endothelial PTB, phosphotyrosine-binding SH2, Src homology 2 YFP, yellow fluorescent protein © 2001 Biochemical Society 2001 1 e...

View article titled, Internalization of the epidermal growth factor receptor: role in signalling

Articles

Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors

K. Siddle, B. Ursø, C. A. Niesler, D. L. Cope, L. Molina, K. H. Surinya, M. A. Soos

Biochem Soc Trans (2001) 29 (4): 513–525.

https://doi.org/10.1042/bst0290513

Published: 01 August 2001

... kinase B; ERK, extra- cellular-signal-regulated kinase; MAPK, mitogen-activated protein kinase; PH, pleckstrin homology; APS, adaptor protein containing PH and 5H2 domains; JAK, ]anus kinase; SOCS, suppressors of cytokine signalling; CAP, c-Cbl-associated protein; PTB, phos- photyrosine binding. 'To whom...

View article titled, Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors

Articles

Regulation of cell cycle re-entry by growth, survival and stress signalling pathways

S.J. Cook, K. Balmanno, A. Garner, T. Millar, C. Taverner, D. Todd

Biochem Soc Trans (2000) 28 (2): 233–240.

https://doi.org/10.1042/bst0280233

Published: 01 February 2000

...-terminal kinase MAPK, mitogen-activated protein kinase MEK, MAPK/ERK kinase MEKK, MEK kinase MKK, MAPK kinase PI3K, phosphoinositide 3’-kinase PKB, protein kinase B pRb, retinoblastoma tumour suppressor protein SAPK, stress-activated protein kinase cyclin-dependent kinases MAP kinases...

View article titled, Regulation of cell cycle re-entry by growth, survival and stress signalling pathways

Articles

Modulation of signal-transduction pathways by chemopreventive agents

M. M. Manson, K. A. Holloway, L. M. Howells, E. A. Hudson, S. M. Plummer, M. S. Squires, S. A. Prigent

Biochem Soc Trans (2000) 28 (2): 7–12.

https://doi.org/10.1042/bst0280007

Published: 01 February 2000

..., extracellular-regulated kinase 13C, indole-3-carbinol JNK, c-Jun N-terminal kinase MAPK, mitogen-activated protein kinase NF-kB, nuclear factor kB IkB, inhibitor of kB IKK, IkB kinase NQO, NAD(P)H:quinone oxidoreductase PDGF, platelet-derived growth factor TNFα, tumour necrosis factor α; CDK, cyclin...

View article titled, Modulation of signal-transduction pathways by chemopreventive agents

Articles

Adipocyte studies: systems for investigating effects of growth hormone and other chronically acting hormones

R. G. Vernon

Biochem Soc Trans (2000) 28 (2): 126–131.

https://doi.org/10.1042/bst0280126

Published: 01 February 2000

... for chronic studies. Use of these various systems for investigating the mechanisms of action of growth hormone are described. 5 8 1999 © 2000 Biochemical Society 2000 adipocytes insulin metabolism tissue culture GH, growth hormone MAPK, mitogen-activated protein kinase PI3 kinase...

View article titled, Adipocyte studies: systems for investigating effects of growth hormone and other chronically acting hormones

Articles

Phosphoinositide 3-kinase signalling: no lipids

M. P. Wymann, L. Pirola, V. L. Katanaev, G. Bulgarelli-Leva

Biochem Soc Trans (1999) 27 (4): 629–634.

https://doi.org/10.1042/bst0270629

Published: 01 August 1999

... product SH2, Src homology 2 PH, pleckstrin homology PKB, protein kinase B PDK, PI-dependent kinase MAPK, mitogen-activated protein kinase ERK, extracellular-signal-regulated kinase MEK, MAPK/ERK kinase Phospholipids: Regulators of Membrane Trafic and Signalling Chang, H. W., Aoki, M., Fruman, D...

View article titled, Phosphoinositide 3-kinase signalling: no lipids

Articles

Cell transformation by ornithine decarboxylase is associated with phosphorylation of the transactivation domain of c-Jun

E. Hölttä, A. Paasinen-Sohns, M. Povelainen, K. Järvinen, K. Ravanko, A. Kangas

Biochem Soc Trans (1998) 26 (4): 621–627.

https://doi.org/10.1042/bst0260621

Published: 01 November 1998

...E. Hölttä; A. Paasinen-Sohns; M. Povelainen; K. Järvinen; K. Ravanko; A. Kangas 1 To whom correspondence should be addressed. 6 7 1998 © 1998 Biochemical Society 1998 Erk, extracellular signal-regulated kinase JNK, c-Jun amino terminal kinase MAPK, mitogen-activated...

View article titled, Cell transformation by ornithine decarboxylase is associated with phosphorylation of the transactivation domain of c-Jun

Articles

Regulation of cytosolic phospholipase A 2 by phosphorylation

A. G. Börsch-Haubold

Biochem Soc Trans (1998) 26 (3): 350–354.

https://doi.org/10.1042/bst0260350

Published: 01 August 1998

...A. G. Börsch-Haubold 24 2 1998 © 1998 Biochemical Society 1998 cPLA2, cytosolic phospholipase A 2 MAPK, mitogen-activated protein kinase MEK, MAPK kinase SAPK, stress-activated protein kinase Biochemical Society Transactions 350 Regulation of cytosolic phospholipase A2...

View article titled, Regulation of cytosolic phospholipase A 2 by phosphorylation

Articles

9 Activation of mitogen-activated protein kinase subfamilies by oxidative stress in the perfused rat heart

Peter H. SUGDEN, Stephen J. FULLER, Ashour MICHAEL, Angela CLERK

Biochem Soc Trans (1997) 25 (4): S565.

https://doi.org/10.1042/bst025s565

Published: 01 November 1997

...Peter H. SUGDEN; Stephen J. FULLER; Ashour MICHAEL; Angela CLERK © 1997 Biochemical Society 1997 ERK, extracellularly-responsive kinase FPLC, fast protein liquid chromatography GST, glutathione- S -transferase MAPK, mitogen-activated protein kinase MAPKAPK2, MAPK-activated protein...

View article titled, 9 Activation of mitogen-activated protein kinase subfamilies by oxidative stress in the perfused rat heart

Articles

10 Mitogen-activated protein kinases are activated by oxidative stress and cytokines in neonatal rat ventricular myocytes

Angela CLERK, Peter H. SUGDEN

Biochem Soc Trans (1997) 25 (4): S566.

https://doi.org/10.1042/bst025s566

Published: 01 November 1997

...Angela CLERK; Peter H. SUGDEN © 1997 Biochemical Society 1997 ERK, extracellularly-responsive kinase FPLC, fast protein liquid chromatography GST, glutathione- S -transferase IL-1β, interleukin-1β MAPK, mitogen-activated protein kinase MAPKAPK2, MAPK-activated protein kinase 2 PMA...

View article titled, 10 Mitogen-activated protein kinases are activated by oxidative stress and cytokines in neonatal rat ventricular myocytes

Articles

A role for the serine/threonine kinase, Akt, in insulin-stimulated glucose uptake

S. A. Summers, M. J. Birnbaum

Biochem Soc Trans (1997) 25 (3): 981–988.

https://doi.org/10.1042/bst0250981

Published: 01 August 1997

...S. A. Summers; M. J. Birnbaum * To whom correspondence should be addressed 7 4 1997 © 1997 Biochemical Society 1997 IRS-1, insulin receptor substrate-1 PI 3-kinase, phosphatidylinositol 3-kinase SH-PTP2, tyrosine phosphatase MAPK, mitogen-activated protein kinase MEK...

View article titled, A role for the serine/threonine kinase, Akt, in insulin-stimulated glucose uptake

Articles

Sphingolipids as differential regulators of cellular signalling processes

S. Pyne, D. G. Tolan, A.-M. Conway, N. Pyne

Biochem Soc Trans (1997) 25 (2): 549–556.

https://doi.org/10.1042/bst0250549

Published: 01 May 1997

...S. Pyne; D. G. Tolan; A.-M. Conway; N. Pyne * To whom correspondence should be addressed. 4 11 1996 © 1997 Biochemical Society 1997 PLC, phospholipase C PLD, phospholipase D PDGF, platelet-derived growth factor MAPK, mitogen-activated protein kinase JNK, c-Jun N...

View article titled, Sphingolipids as differential regulators of cellular signalling processes

Articles

A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production

STEPHEN G. WARD, RICHARD V. PARRY, JANE MATTHEWS, LUKE O'NEILL

Biochem Soc Trans (1997) 25 (2): 304S.

https://doi.org/10.1042/bst025304s

Published: 01 May 1997

... driven proliferation of Abbreviations: CHO, Chinese hamster ovary cells; ERK, extracellular-signal regulated kinase; JNK, c-Jun kinase; PI3K, phosphatidylinositol 3-kinase; PMA, phorbol 12-myristate 13- acetate; MAPK, mitogen-activated protein kinase ; SAPK, stress- activated protein kinases SB203580...

View article titled, A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production

Articles

Regulation of Raf-I kinase by interaction with the lipid second messenger, phosphatidic acid

S. Ghosh, R. M. Bell

Biochem Soc Trans (1997) 25 (2): 561–565.

https://doi.org/10.1042/bst0250561

Published: 01 May 1997

...S. Ghosh; R. M. Bell * To whom correspondence should be addressed. 31 10 1996 © 1997 Biochemical Society 1997 PA, phosphatidic acid MAPK, mitogen-activated protein kinase PKC, protein kinase C DAG, diacylglycerol PS, phosphatidylserine CRD, cysteine-rich domain PLD...

View article titled, Regulation of Raf-I kinase by interaction with the lipid second messenger, phosphatidic acid

Articles

Protein kinase D: a novel target for diacylglycerol and phorbol esters

E. Rozengurt, J. Sinnett-Smith, J. L. Zugaza

Biochem Soc Trans (1997) 25 (2): 565–571.

https://doi.org/10.1042/bst0250565

Published: 01 May 1997

... kinase PDB, phorbol 12,13-dibutyrate PS, phosphatidylserine MAPK, mitogen-activated protein kinase Lipids as Regulators of Cell Function 8 9 10 1 1 12 13 Hommel, U., Zurini, M. and Luyten, M. (1994) Nature (Struct. Biol.) 1, 383-387 Ghosh, S., Xie, W. Q., Quest, A. F. G., Mabrouk, G., Strum, J. C...

View article titled, Protein kinase D: a novel target for diacylglycerol and phorbol esters

Articles

Cell death signal transduction and Bcl-2 function

J. L. Herrmann, E. Bruckheimer, T. J. McDonnell

Biochem Soc Trans (1996) 24 (4): 1059–1065.

https://doi.org/10.1042/bst0241059

Published: 01 November 1996

... PLA 2 , phospholipase A 2 SAPK/JNK, stress-activated protein kinase/Jun kinase MAPK, mitogen-activated protein kinase SMase, sphingomyelinase PT, permeability transition IκBα, inhibitor of κBα Cell Death Mechanisms Cell death signal transduction and Bcl-2 function J. L. Herrmann, E...

View article titled, Cell death signal transduction and Bcl-2 function

Articles

Rational design of Ras prenyltransferase inhibitors as potential anticancer drugs

S. M. Sebti, A. D. Hamilton

Biochem Soc Trans (1996) 24 (3): 692–699.

https://doi.org/10.1042/bst0240692

Published: 01 August 1996

...S. M. Sebti; A. D. Hamilton 26 3 1996 © 1996 Biochemical Society 1996 GGTase-I, geranylgeranyltransferase I MAPK, mitogen-activated protein kinase FTase, farnesyltransferase Biochemical Society Transactions 692 Silverman, K. C., I3ills, G. I Mosley, R. I Gibbs, J. B. et al...

View article titled, Rational design of Ras prenyltransferase inhibitors as potential anticancer drugs

Articles

Transcriptional regulation of the betaine/γ-aminobutyric acid transporter by hypertonicity

H. M. Kwon

Biochem Soc Trans (1996) 24 (3): 853–856.

https://doi.org/10.1042/bst0240853

Published: 01 August 1996

...H. M. Kwon 1 3 1996 © 1996 Biochemical Society 1996 GABA, γ-aminobutyric acid BGT1, betaine/GABA transporter TonE, tonicityresponse sequence element TonEBP, TonE-binding protein MAPK, mitogen-activated protein kinase ERK, extracellular-signal-regulated protein kinase...

View article titled, Transcriptional regulation of the betaine/γ-aminobutyric acid transporter by hypertonicity

Articles

The role of G-protein βγsubunits in signal transduction

S. Müller, M. J. Lohse

Biochem Soc Trans (1995) 23 (1): 141–148.

https://doi.org/10.1042/bst0230141

Published: 01 February 1995

...S. Müller; M. J. Lohse * To whom correspondence should be addressed. 19 9 1994 © 1995 Biochemical Society 1995 βARK, β-adrenergic receptor kinase GRK, G-protein-coupled receptor kinase MAPK, mitogen-activated protein kinase PI3K, phosphoinositide 3-kinase RK, rhodopsin...

View article titled, The role of G-protein βγsubunits in signal transduction

Articles

Insulin signalling and the stimulation of glucose transport

Brian E. Lavan, Gustav E. Lienhard

Biochem Soc Trans (1994) 22 (3): 676–680.

https://doi.org/10.1042/bst0220676

Published: 01 August 1994

...Brian E. Lavan; Gustav E. Lienhard * To whom correspondence should be addressed. 17 3 1994 © 1994 Biochemical Society 1994 CHO, Chinese hamster ovary EGF, epidermal growth factor IRS-1, insulin receptor substrate-1 MAPK, mitogen-activated protein kinase MAPKK, MAPK...

View article titled, Insulin signalling and the stimulation of glucose transport

NARROW

Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

Adrenomedullin: receptor and signal transduction

Coagulation proteases and human cancer

Statins for the prevention of vein graft stenosis: a role for inhibition of matrix metalloproteinase-9

Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents

Internalization of the epidermal growth factor receptor: role in signalling

Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors

Regulation of cell cycle re-entry by growth, survival and stress signalling pathways

Modulation of signal-transduction pathways by chemopreventive agents

Adipocyte studies: systems for investigating effects of growth hormone and other chronically acting hormones

Phosphoinositide 3-kinase signalling: no lipids

Cell transformation by ornithine decarboxylase is associated with phosphorylation of the transactivation domain of c-Jun

Regulation of cytosolic phospholipase A 2 by phosphorylation

9 Activation of mitogen-activated protein kinase subfamilies by oxidative stress in the perfused rat heart

10 Mitogen-activated protein kinases are activated by oxidative stress and cytokines in neonatal rat ventricular myocytes

A role for the serine/threonine kinase, Akt, in insulin-stimulated glucose uptake

Sphingolipids as differential regulators of cellular signalling processes

A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production

Regulation of Raf-I kinase by interaction with the lipid second messenger, phosphatidic acid

Protein kinase D: a novel target for diacylglycerol and phorbol esters

Cell death signal transduction and Bcl-2 function

Rational design of Ras prenyltransferase inhibitors as potential anticancer drugs

Transcriptional regulation of the betaine/γ-aminobutyric acid transporter by hypertonicity

The role of G-protein βγsubunits in signal transduction

Insulin signalling and the stimulation of glucose transport

Email alerts

CONNECT

EXPLORE

Email alerts

CONNECT

EXPLORE

This Feature Is Available To Subscribers Only