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Keywords: MeCP2
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (4): 575–583.
Published: 22 July 2008
...Adrian Bird The methyl-CpG-binding protein MeCP2 was discovered over 15 years ago as part of a search for proteins that selectively bind methylated DNA. It is a nuclear protein that is largely chromatin-bound and has a strong preference for binding to methylated DNA sequences in vivo . Evidence...
