... resonance (NMR) spectroscopy being most widely used. However, reported binding affinities are inconsistent. At the extreme, for the same system MS detects binding whereas NMR spectroscopy does not, suggesting a fundamental source of error. In this short essay, we will explain the reason for the observed...

... on behalf of the Biochemical Society 2021 ABC transporter EPR spectroscopy NMR spectroscopy structural biology The superfamily of ABC transporters contains a variety of proteins from all domains of life that fulfil a multitude of functions in cellular processes. Defects in ABC transporters...

... of the Biochemical Society 2021 dynamic nuclear polarization membrane lipids NMR spectroscopy protein structure protein–protein interactions transmembrane proteins Cell membranes are self-assembled structures, which enclose the principal compartments of life and define the cell as its fundamental...

... 10.3389/fncel.2019.00309 7 Luchinat , E. , Barbieri , L. , Cremonini , M. and Banci , L. ( 2021 ) Protein in-cell NMR spectroscopy at 1.2 GHz . J. Biomol. NMR 75 , 97 – 107 10.1007/s10858-021-00358-w 8 Broft , P. , Dzatko , S. , Krafcikova , M. , Wacker...

... 4 9 2018 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 allostery dynamics NMR spectroscopy small G proteins Small G proteins of the Ras superfamily are essential components in almost all aspects of cell biology and since...

... of the Biochemical Society 2017 aurora kinases crystallography intrinsically disordered proteins NMR spectroscopy Myc proteins are transcription factors that markedly alter gene expression through both activation and repression [ 1 – 3 ]. The three Myc protein family members in humans (c-Myc, N-Myc...

... 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 atrogene NMR spectroscopy p62 Paget's disease of bone (PDB) sequestosome 1 (SQSTM1) ubiquitin-associated domain (UBA domain) PTM (post-translational modification) of proteins through ubiquitination...

... (HMG box) high-mobility group protein B1 (HMGB1) histone H1 histone H3 NMR spectroscopy p53 Histone H1 and HMGB1 (high-mobility group protein B1) are considered together in the present paper because these two structurally unrelated proteins, whose modes of binding to chromatin...

...@bioch.ox.ac.uk ). Intermolecular Associations in 2D and 3D, a Biochemical Society Focused Meeting held at University of Nottingham, 19–20 June 2003 20 June 2003 © 2003 Biochemical Society 2003 NMR spectroscopy protein–ligand interactions solution-state NMR Abbreviations used...