...Colin Lockwood; Julea N. Butt; Thomas A. Clarke; David J. Richardson The cytochrome c nitrite reductase NrfA is a 53 kDa pentahaem enzyme that crystallizes as a decahaem homodimer. NrfA catalyses the reduction of NO 2 − to NH 4 + through a six electron reduction pathway that is of major...

... tetrahaem cytochrome that directly mediates electron transfer from the hydroquinone pool to NrfA ( Figure 1 B). A recent solved structure of a Desulfovibrio vulgaris NrfA–NrfH complex showed an α 4 β 2 arrangement with two NrfA dimers bound to one NrfH dimer [ 12 ]. In contrast with the NrfA–NrfB complex...

...T.A. Clarke; A.M. Hemmings; B. Burlat; J.N. Butt; J.A. Cole; D.J. Richardson The recent crystallographic characterization of NrfAs from Sulfurospirillum deleyianum , Wolinella succinogenes , Escherichia coli and Desulfovibrio desulfuricans allows structurally conserved regions to be identified...