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Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase

Biochem Soc Trans (1997) 25 (2): 374–381.

https://doi.org/10.1042/bst0250374

Published: 01 May 1997

... 1997 PKA, protein kinase A AKAP, PKA-anchoring protein PDE, phosphodiesterase UCR, upstream conserved region SH3, Src homology 3 Session 3: Structure and Function: 660th Meeting Joint Congress with the British Society for Immunology, held at Harrogate, 10–13 December 1996...

View article titled, Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase

Articles

The N-terminal alternately spliced regions of PDE4A cAMP-specific phosphodiesterases determine intracellular targeting and regulation of catalytic activity

M. D. Houslay

Biochem Soc Trans (1996) 24 (4): 980–986.

https://doi.org/10.1042/bst0240980

Published: 01 November 1996

...M. D. Houslay 31 5 1996 © 1996 Biochemical Society 1996 PDE, phosphodiesterase CAT, chloramphenicol acetyltransferase SH3 domain, Src homology domain 3 Biochemical Society Transactions 980 43 44 45 46 47 48 Wu, D., Katz, A. and Simon, M. I . (1993) Proc. Natl. Acad. Sci...

View article titled, The N-terminal alternately spliced regions of PDE4A cAMP-specific phosphodiesterases determine intracellular targeting and regulation of catalytic activity

Articles

Multiplicity within cyclic nucleotide phosphodiesterases

S. D. Rybalkin, J. A. Beavo

Biochem Soc Trans (1996) 24 (4): 1005–1009.

https://doi.org/10.1042/bst0241005

Published: 01 November 1996

...S. D. Rybalkin; J. A. Beavo * To whom correspondence should be addressed. 30 5 1996 © 1996 Biochemical Society 1996 PDE, phosphodiesterase CaM, calmodulin EHNA, erythro-9-(2-hydroxy-3-nonyl) adenine Signal Termination and Compartmentalization 17 18 19 20 21 22 23 24 25...

View article titled, Multiplicity within cyclic nucleotide phosphodiesterases

Articles

cGMP-inhibited phosphodiesterases (PDE3 gene family)

E. Degerman, P. Belfrage, V. C. Manganiello

Biochem Soc Trans (1996) 24 (4): 1010–1014.

https://doi.org/10.1042/bst0241010

Published: 01 November 1996

...E. Degerman; P. Belfrage; V. C. Manganiello ‡ To whom correspondence should be addressed. 12 7 1996 © 1996 Biochemical Society 1996 PDE, phosphodiesterase cGI, cGMP-inhibited H, human R, rat PI3-K, phosphatidylinositol 3-kinase IRS-1, insulin-receptor substrate-1...

View article titled, cGMP-inhibited phosphodiesterases (PDE3 gene family)

Articles

cGMP signal termination

N. J. Pyne, V. Arshavsky, A. Lochhead

Biochem Soc Trans (1996) 24 (4): 1019–1022.

https://doi.org/10.1042/bst0241019

Published: 01 November 1996

...N. J. Pyne; V. Arshavsky; A. Lochhead ‡ To whom correspondence should be addressed. 29 5 1996 © 1996 Biochemical Society 1996 PDE, phosphodiesterase PKG, protein kinase G PKA, protein kinase A ASM, airway smooth muscle Signal Termination and Compartmentalization 39 40...

View article titled, cGMP signal termination

Articles

Alternative splicing of the type-IVA cyclic AMP phosphodiesterase gene provides isoform variants with distinct N-terminal domains fused to a common, soluble catalytic unit: ‘designer’ changes in V max , stability and membrane association

M. D. Houslay, G. Scotland, L. Pooley, S. Spence, I. Wilkinson, F. McCallum, P. Julien, N. G. Rena, A. M. Michie, S. Erdogan, L. Zeng, J. C. O'Connell, E. S. Tobias, I. MacPhee

Biochem Soc Trans (1995) 23 (2): 393–398.

https://doi.org/10.1042/bst0230393

Published: 01 May 1995

... surface. Secondly, the specific detector system, namely a PKA isoform, must be selectively local- ~~ ~~ ~ ~~ Abbreviations used: CAMP, cyclic AMP; PKA, CAMP- dependent protein kinase; PDE, phosphodiesterase; Met -RD1, RDl lacking the N-terminal 25 amino acids; CAT, chloramphenical acetyltransferase...

View article titled, Alternative splicing of the type-IVA cyclic AMP phosphodiesterase gene provides isoform variants with distinct N-terminal domains fused to a common, soluble catalytic unit: ‘designer’ changes in V max , stability and membrane association

Articles

Regulation of intracellular cyclic AMP concentrations in hepatocytes involves the integrated activation and desensitization of adenylyl cyclase coupled with the action and activation of specific isoforms of cyclic AMP phosphodiesterase

Miles D. Houslay, Susanne L. Griffiths, Yvonne M. Horton, Callum Livingstone, Margaret Lobban, Fiona Macdonald, Nicholas Morris, James Pryde, Grant Scotland, Yasmin Shakur, Gary Sweeney, Eric K. Y. Tang

Biochem Soc Trans (1992) 20 (1): 140–146.

https://doi.org/10.1042/bst0200140

Published: 01 February 1992

... Society 1992 G s , stimulatory G-protein G i , inhibitory G-protein PDE, phosphodiesterase PPM, peripheral plasma membrane DV, dense vesicle Biochemical Society Transactions I40 18. 19. 20. 21. 22. Milligan, G., Unson, C. G. & Wakelam, M. J. 0. (1989) Biochem. J. 262,643-649 Mitchell, F. M...

View article titled, Regulation of intracellular cyclic AMP concentrations in hepatocytes involves the integrated activation and desensitization of adenylyl cyclase coupled with the action and activation of specific isoforms of cyclic AMP phosphodiesterase

Articles

Modulation of rod cyclic GMP-phosphodiesterase activity by anthocyanidin derivatives

NOËLLE VIRMAUX, JEAN-CLAUDE BIZEC, GÉRARD NULLANS, SYLVIANE EHRET, PAUL MANDEL

Biochem Soc Trans (1990) 18 (4): 686–687.

https://doi.org/10.1042/bst0180686

Published: 01 August 1990

...NOËLLE VIRMAUX; JEAN-CLAUDE BIZEC; GÉRARD NULLANS; SYLVIANE EHRET; PAUL MANDEL 27 11 1989 © 1990 Biochemical Society 1990 PDE, phosphodiesterase ROS, rod outer segments IBMX, isobutylmethylxanthine 633rd Meeting London: 633rd Meeting Held at St Bartholomew's Hospital...

View article titled, Modulation of rod cyclic GMP-phosphodiesterase activity by anthocyanidin derivatives

Articles

The insulin-sensitivity of phosphodiesterase activities released by hypotonic extraction of hepatocyte particulate fractions

NEIL G. ANDERSON, MILES D. HOUSLAY

Biochem Soc Trans (1989) 17 (1): 217.

https://doi.org/10.1042/bst0170217

Published: 01 February 1989

...NEIL G. ANDERSON; MILES D. HOUSLAY 3 6 1988 © 1989 Biochemical Society 1989 PDE, phosphodiesterase 627th Meeting Nottingham: 627th Meeting Held at the University of Nottingham, 20–22 July 1988 627th MEETING. NOTTINGHAM 217 The insulin-sensitivity of phosphodiesterase...

View article titled, The insulin-sensitivity of phosphodiesterase activities released by hypotonic extraction of hepatocyte particulate fractions

Articles

Mammalian G proteins: structure and function

HENRY R. BOURNE, SUSAN B. MASTERS, KATHLEEN A. SULLIVAN

Biochem Soc Trans (1987) 15 (1): 35–38.

https://doi.org/10.1042/bst0150035

Published: 01 February 1987

...HENRY R. BOURNE; SUSAN B. MASTERS; KATHLEEN A. SULLIVAN 15 7 1986 © 1987 Biochemical Society 1987 PDE, phosphodiesterase PLC, phospholipase C α 2 , σ 1 , σ 0 , σ t1 and σ t2 , α-chains of G s , G, i , G o and transducins-1 and -2 βγ 1 βγ t1 and γ t2 , the indicated...

View article titled, Mammalian G proteins: structure and function

Articles

Mapping the binding sites of transducin by sequence homology, chemical modification, and by using monoclonal antibodies

BERNARD KWOK-KEUNG FUNG, SAMUEL E. NAVON

Biochem Soc Trans (1987) 15 (1): 39–42.

https://doi.org/10.1042/bst0150039

Published: 01 February 1987

...BERNARD KWOK-KEUNG FUNG; SAMUEL E. NAVON 18 7 1986 © 1987 Biochemical Society 1987 ROS, rod outer segment R, rhodopsin R * , active intermediate of rhodopsin T, transducin PDE, phosphodiesterase mAb, monoclonal antibody 619th MEETING, C A M B R I D G E 39 Mapping...

View article titled, Mapping the binding sites of transducin by sequence homology, chemical modification, and by using monoclonal antibodies

NARROW

Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase

The N-terminal alternately spliced regions of PDE4A cAMP-specific phosphodiesterases determine intracellular targeting and regulation of catalytic activity

Multiplicity within cyclic nucleotide phosphodiesterases

cGMP-inhibited phosphodiesterases (PDE3 gene family)

cGMP signal termination

Alternative splicing of the type-IVA cyclic AMP phosphodiesterase gene provides isoform variants with distinct N-terminal domains fused to a common, soluble catalytic unit: ‘designer’ changes in V max , stability and membrane association

Regulation of intracellular cyclic AMP concentrations in hepatocytes involves the integrated activation and desensitization of adenylyl cyclase coupled with the action and activation of specific isoforms of cyclic AMP phosphodiesterase

Modulation of rod cyclic GMP-phosphodiesterase activity by anthocyanidin derivatives

The insulin-sensitivity of phosphodiesterase activities released by hypotonic extraction of hepatocyte particulate fractions

Mammalian G proteins: structure and function

Mapping the binding sites of transducin by sequence homology, chemical modification, and by using monoclonal antibodies

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