...Oscar Muñoz; Mlana Lore; Sujatha Jagannathan Nonsense-mediated RNA decay (NMD) plays a dual role as an RNA surveillance mechanism against aberrant transcripts containing premature termination codons and as a gene regulatory mechanism for normal physiological transcripts. This dual function...

... oocytes [ 26 ], where no active transcription persists [ 33 ], strongly suggesting that the RNA decay pathways are active in growing wild-type oocytes. A recent study has indicated that 3′ uridylation of 700 mRNAs with very short poly(A) tails by the terminal 3′ uridylyl transferases, TUT4 and TUT7...

... 2017 20 12 2017 © 2018 The Author(s) 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . degradosome exosome RNA decay RNA helicases All...

... in cellular growth and organism development. gene expression nonsense-mediated mRNA decay (NMD) premature termination codon (PTC) RNA decay RNA processing RNA quality control © The Authors Journal compilation © 2010 Biochemical Society 2010 7 6 2010 1 To whom...

... binding cytoplasmic polyadenylation element-binding protein (CPEB) processing body (P-body) RNA decay stress granule translation initiation Regulation of gene expression at the level of translation is an important level of control in eukaryotes and is essential in early development...