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Keywords: RNA interference
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Biochem Soc Trans (2023) 51 (1): 137–146.
Published: 06 January 2023
...Dario Pasquale Anobile; Enzo Z. Poirier Antiviral RNA interference (RNAi) is an immune pathway that can, in certain conditions, protect mammalian cells against RNA viruses. It depends on the recognition and dicing of viral double-stranded RNA by a protein of the Dicer family, which leads...
Biochem Soc Trans (2016) 44 (5): 1355–1365.
Published: 19 October 2016
... and adverse effects. Therefore, more durable therapeutic strategies should be considered, such as a stable gene therapy to protect the target T cells against HIV-1 infection. The development of potent therapeutic regimens based on the RNA interference (RNAi) and clustered regularly interspaced short...
Biochem Soc Trans (2013) 41 (6): 1464–1467.
Published: 20 November 2013
.... The possible in vivo targets, as well as our current knowledge of the Cmr complex, is reviewed in the present paper. clustered regularly interspaced short palindromic repeats (CRISPR) Cmr repeat-associated mysterious protein (RAMP) RNA interference metal ion nuclease 1 email scbailey...
Biochem Soc Trans (2005) 33 (4): 643–645.
Published: 01 August 2005
... ARL stands for ARF-like) encoded in the T. brucei and T. cruzi genomes and ten in L. major . The T. brucei ARL1 protein is expressed only in the mammalian bloodstream form of the parasite, in which it is localized to the Golgi apparatus. RNAi (RNA interference) has been used to demonstrate that ARL1...
Biochem Soc Trans (2005) 33 (3): 471–473.
Published: 01 June 2005
... by RNA interference causes an increase in the number of cells in S-phase and this effect can be reversed by expressing an exogenous SLBP resistant to the small interfering RNA. Cells with decreased SLBP levels progress slowly through S-phase when released from a double-thymidine block. Thus SLBP...