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Keywords: RNA interference
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 281–291.
Published: 06 February 2025
... drosophila meiotic drive piRNA pathway RNA interference In sexually reproducing organisms, meiosis is a process by which haploid gametes (e.g. egg and sperm cells) are produced from diploid parental cells [ 1 ]. One of the hallmarks of meiosis is the equal segregation of genes/alleles [ 2...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 137–146.
Published: 06 January 2023
...Dario Pasquale Anobile; Enzo Z. Poirier Antiviral RNA interference (RNAi) is an immune pathway that can, in certain conditions, protect mammalian cells against RNA viruses. It depends on the recognition and dicing of viral double-stranded RNA by a protein of the Dicer family, which leads...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1355–1365.
Published: 19 October 2016
... and adverse effects. Therefore, more durable therapeutic strategies should be considered, such as a stable gene therapy to protect the target T cells against HIV-1 infection. The development of potent therapeutic regimens based on the RNA interference (RNAi) and clustered regularly interspaced short...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (6): 1464–1467.
Published: 20 November 2013
... (CRISPR) Cmr repeat-associated mysterious protein (RAMP) RNA interference metal ion nuclease Immune pathways protect all organisms from infection by mobile genetic elements such as viruses. It was recently discovered that prokaryotes control such infection via an RNA-based adaptive immune...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (4): 643–645.
Published: 01 August 2005
... ARL stands for ARF-like) encoded in the T. brucei and T. cruzi genomes and ten in L. major . The T. brucei ARL1 protein is expressed only in the mammalian bloodstream form of the parasite, in which it is localized to the Golgi apparatus. RNAi (RNA interference) has been used to demonstrate that ARL1...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (3): 471–473.
Published: 01 June 2005
... by RNA interference causes an increase in the number of cells in S-phase and this effect can be reversed by expressing an exogenous SLBP resistant to the small interfering RNA. Cells with decreased SLBP levels progress slowly through S-phase when released from a double-thymidine block. Thus SLBP...