.... cellular localization gene expression and regulation molecular scaffolds RNA localization translation The intracellular space is a highly complex environment where synchronised and simultaneous molecular processes determine cell function and behaviour. To ensure efficiency and fidelity...

... by which cells can generate subcellular microenvironments with specialized gene expression profiles. Particularly intriguing are recent findings that phase separation plays a role in certain RNA localization pathways. The burgeoning field of phase separation has revolutionized how we view cellular...

... change. Correspondence: Jeffrey A. Chao ( [email protected] ) 2 7 2021 20 8 2021 23 8 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 local translation neuron RNA localization single-molecule Neurons...

... BY) . alternative splicing biological networks gene expression and regulation intrinsically disordered proteins protein turnover RNA localization Understanding how proteins, which are polymers of amino acids, carry out different functions in a cell has been a problem of considerable interest...

... of gene expression in the testis yields information regarding both temporal and cell-type-specific regulation of transcription. As cells in the testis are large, transcripts with specific subcellular RNA localizations are readily identified. The primary spermatocyte period is characterized by high...