...Judith Zoephel; Lennart Randau In bacteria and archaea, RNA-Seq deep sequencing methodology allows for the detection of abundance and processing sites of the small RNAs that comprise a CRISPR (clustered regularly interspaced short palindromic repeats) RNome. Comparative analyses of these CRISPR...

...-generation sequencing is also changing the ways in which gene expression is studied, which is likely to have much future impact. Complex RNA mixtures can be analysed using sequence census methods, an approach termed ‘RNA-Seq’. Initial applications include the accelerated discovery of small RNAs [ 37 – 40...