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Keywords: RTK
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Articles
Edmond M. Linossi, Gabriella O. Estevam, Masaya Oshima, James S. Fraser, Eric A. Collisson, Natalia Jura
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 645–661.
Published: 16 April 2021
...Edmond M. Linossi; Gabriella O. Estevam; Masaya Oshima; James S. Fraser; Eric A. Collisson; Natalia Jura The MET receptor tyrosine kinase (RTK) and its cognate ligand hepatocyte growth factor (HGF) comprise a signaling axis essential for development, wound healing and tissue homeostasis. Aberrant...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1167–1176.
Published: 05 May 2020
... between PDGFRα and PDGFRβ in the region C-terminal to TK2 (28%) [ 6 ], so if a similar autoinhibitory mechanism is at play for PDGFRα, it must involve a distinct motif [ 27 ]. PDGFR RTK signaling Receptor tyrosine kinases (RTKs) are a group of single-pass transmembrane proteins which...