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Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (1): 291–300.
Published: 12 February 2020
... in the PI3K pathway. The development of small molecules that selectively target one of the SHIP paralogs (SHIP1 or SHIP2) as well as inhibitors that simultaneously target both enzymes have provided promising data linking the phosphatase activity of the SHIP enzymes to disorders and disease states...