...Kyoung-Wook Moon; Je-Kyung Ryu Structural maintenance of chromosome (SMC) proteins play a key roles in the chromosome organization by condensing two meters of DNA into cell-sized structures considered as the SMC protein extrudes DNA loop. Recent sequencing-based high-throughput chromosome...

... BY) . archaea CID cohesin condensin SMC TAD The seminal studies of Woese and Fox revealed Archaea to be a distinct domain of life from Bacteria and Eukaryotes [ 1 ]. More recent advances in phylogenetic methods, coupled with massively increased taxonomic sampling have revealed deep divisions...

... of the overarching SMC superfamily. * Present address: Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge, CB3 0AS, U.K. 24 3 2018 19 10 2020 22 10 2020 © 2020 The Author(s) 2020 This is an open access article published...

...Erin E. Cutts; Alessandro Vannini Condensin and cohesin, both members of the structural maintenance of chromosome (SMC) family, contribute to the regulation and structure of chromatin. Recent work has shown both condensin and cohesin extrude DNA loops and most likely work via a conserved mechanism...