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Keywords: Smad3
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (4): 661–664.
Published: 20 July 2007
... receptor and signalling molecules Smad2 and Smad3. Transient gene transfer of either TGF-β1 or IL-1β to Smad3-null mouse lung provides little evidence of progressive fibrosis and no fibrogenesis-associated genes are induced. These results suggest that mechanisms of progressive fibrosis involve factors...
