... Attribution License 4.0 (CC BY-NC-ND) . Correspondence: Federica Brandizzi ( [email protected] ) 19 1 2024 23 3 2024 2 4 2024 Arabidopsis thaliana cell-fate ER stress post translational modification programmed cell death UPR The endoplasmic reticulum (ER) performs...

... of the Biochemical Society 2024 autophagy ISR neurons nutrient stress proteome UPR In response to nutrient scarcity, cells adapt to stress by modulating the balance between protein synthesis through mRNA transcription-translation and protein degradative pathways [ 11–13 ]. Although protein...

... to radiobiological hypoxia is one of few physiologically relevant stresses that activates both the unfolded protein and DNA damage responses (UPR and DDR). Links between these pathways have been identified in studies carried out in normoxia. Based in part on these previous studies and recent work from our laboratory...

... 2020 endoplasmic reticulum LTK proteostasis tyrosine kinase UPR A third of the eukaryotic proteome harbors signal sequences that target these proteins to the ER. One of the main functions of the ER is to fold and quality control these proteins. In addition, a cytosolic machinery...