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Keywords: Warburg effect
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Biochem Soc Trans (2016) 44 (5): 1499–1505.
Published: 19 October 2016
... the mitochondria in cancer cells to be functional across a range of tumour types. However, different tumour populations have different bioenergetic alterations in order to meet their high energy requirement; the Warburg effect is not consistent across all cancer types. This review will discuss the metabolic...
Biochem Soc Trans (2013) 41 (1): 124–126.
Published: 29 January 2013
... effect, postulated in 1929, has languished in the shadow of the Warburg effect in terms of research attention [ 4 ]. The Crabtree effect is simply defined as the observation that high concentrations of glucose result in a decrease in mitochondrial respiration in cancer cells [ 4 ]. The role of inhibited...
Biochem Soc Trans (2012) 40 (2): 311–323.
Published: 21 March 2012
... of metabolically derived inputs into the signalling system and the regulation of transcription. I also discuss the Warburg effect where the cross-talk between metabolism and signalling is used to orchestrate rapid cell growth and division. It is becoming clear that future research will concentrate...