...Pablo Astudillo The Wnt/β-catenin signaling pathway plays fundamental roles during development, stem cell differentiation, and homeostasis, and its abnormal activation can lead to diseases. In recent years, it has become clear that this pathway integrates signals not only from Wnt ligands but also...

...Claudia Y. Janda; K. Christopher Garcia Wnt proteins are conserved signalling molecules that have an essential role in regulating diverse processes during embryogenesis and adult tissue homoeostasis. Wnts are post-translationally modified by palmitoylation, which is essential for Wnt secretion...

..., the Wnt, Hedgehog (Hh) and Ghrelin proteins. Given their important roles in adult tissue homoeostasis, all three molecules and their respective associated acyltransferases provide a framework for interrogating the role of extracellular acylation events in cell-to-cell communication. Here, we discuss how...

...Bente Kofahl; Jana Wolf The Wnt/β-catenin pathway plays an important role in development and disease. Theoretical approaches have been used to describe this pathway and have provided intriguing insights into its signalling characteristics. In the present paper, we review mathematical models...

... responses to lithium. 1 To whom correspondence should be addressed (email [email protected] ). 27 5 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 behaviour bipolar disorder glycogen synthase kinase 3 (GSK3) inositol lithium Wnt...