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Keywords: amino acid transporter
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Articles
Amino acid transporters: éminences grises of nutrient signalling mechanisms?
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 237–241.
Published: 20 January 2009
... circumstances, as transporter-like sensors (or ‘transceptors’) upstream of mTOR. 1 email [email protected] 12 9 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 amino acid transporter general control non-derepressible (GCN) mitogen-activated protein...
Articles
Amino acid sensing and mTOR regulation: inside or out?
Available to PurchaseDeborah C.I. Goberdhan, Margret H. Ögmundsdóttir, Shubana Kazi, Bruno Reynolds, Shivanthy M. Visvalingam, Clive Wilson, C.A. Richard Boyd
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 248–252.
Published: 20 January 2009
... Society 2009 amino acid transporter mammalian target of rapamycin (mTOR) proton-assisted amino acid transporter (PAT) Ras-related GTPase (Rag) solute carrier 36A1 (SLC36A1) mTOR initially came to light as the cellular target for the immunosuppressant drug rapamycin. Since...
Articles
Amino acid transporters and nutrient-sensing mechanisms: new targets for treating insulin-linked disorders?
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (5): 1215–1217.
Published: 25 October 2007
...-assisted a mino acid t ransporters) as having a uniquely potent role in regulating IIS/TOR activity and growth, potentially via a novel signalling mechanism. Other molecules such as the heterodimeric amino acid transporter, CD98, which provides the principal route for cellular uptake of leucine, an amino...