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Keywords: aminoacyl-tRNA synthetase
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Biochem Soc Trans (2024) 52 (3): 1149–1158.
Published: 30 May 2024
.... aminoacyl-tRNA synthetase indoleamine 2 3-dioxygenase interferon-γ tryptophan tryptophanyl-tRNA synthetase Mammalian cells cannot synthesize L-tryptophan (Trp). Given that Trp does not freely diffuse across the cell membrane it must be transported. Uptake of large hydrophobic amino acids...
Biochem Soc Trans (2024) 52 (2): 661–670.
Published: 13 March 2024
...Pallob Barai; Jie Chen Aminoacyl-tRNA synthetases (AARSs) play an indispensable role in the translation of mRNAs into proteins. It has become amply clear that AARSs also have non-canonical or non-translational, yet essential, functions in a myriad of cellular and developmental processes...
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Biochem Soc Trans (2023) 51 (6): 2127–2141.
Published: 18 December 2023
...Debjit Khan; Paul L. Fox Aminoacyl-tRNA synthetases (aaRSs) are ancient enzymes that serve a foundational role in the efficient and accurate translation of genetic information from messenger RNA to proteins. These proteins play critical, non-canonical functions in a multitude of cellular processes...