... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . animal model experimental Parkinson's disease invertebrates toxicology Parkinson's disease (PD) is a chronic...

... leading to bone erosion. Failure to resolve the acute phase of inflammation in the joint leads to chronicity with resultant joint damage and disability. animal model immunoglobulin heavy-chain-binding protein (BiP) inflammation moonlighting protein rheumatoid arthritis stress protein therapy...

... pathological disease spectrum. Recently, coding mutations have been identified in the TDP-43 gene ( TARDBP ), which further confirmed the pathogenic nature of the protein. Today, several animal models have been generated to gain more insight into the disease-causing pathways of the FTLD/ALS spectrum. This mini...

... and efficacy of the mucosal protective barrier. Animal models of IBD have been developed to gain further knowledge of the disease mechanisms. These topics form an overlapping background to enable an improved understanding of the molecular features of these diseases. A series of articles is presented based...

... disease (AD) animal model apolipoprotein E (apoE) cognitive impairment neurodegeneration AD (Alzheimer's disease) causes progressive, irreversible loss of cognitive function and is characterized by two neuropathological hallmarks: extracellular amyloid plaques and intracellular NFTs...

... collaborators have used animal models to show that acute systemic inflammatory activation superimposed on existing progressive neurodegeneration can produce acute exacerbation of behavioural and cognitive function, resembling delirium, and can also induce acute neuronal death and accelerate the progression...

... content increases with age and is exacerbated by IR, suggestive of pro-atherogenic remodelling. The focus of this review is to contribute to the perspective of PP lipaemia in CVD risk associated with the metabolic syndrome through the use of animal models. 1 To whom correspondence should...